70results about How to "Achieving Security Guarantees" patented technology

A method for operating a combination touch pad and display screen device as a PINpad for entering a A plurality of numerical keypad layouts for the display screen are defined. Each keypad layout has a unique arrangement of decimal number locations differing from one layout to all others. For each PIN entry event a random one of the numerical keypad layouts is selected and displayed on the display screen.

A system and method for ameliorating spinal column anomalies, such as scoliosis, includes bone screws which are to be implanted in the pedicle region(s) of individual to-be-derotated vertebrae and in vertebrae to which balancing forces must be applied as the spinal column is manipulated en mass to achieve an over-all correction of the condition. A pedicle screw cluster derotation tool simultaneously engages multiple pedicle screws and transmits manipulative forces to multiple vertebrae to effect a whole-spine correction. Pre-contoured spinal rods are engaged post-derotation to secure the correction.

Methods of treating MDS, or ameliorating a symptom thereof, are disclosed. Specific methods encompass the administration of one or more vitamin D compounds, or a pharmaceutically acceptable salt, solvate, hydrate, stereoisomer, clathrate, or prodrug thereof, alone or in combination with one or more additional active agents. Other methods include intermittent administration of a high dose of one or more vitamin D compounds, or a pharmaceutically acceptable salt, solvate, hydrate, stereoisomer, clathrate, or prodrug thereof, alone or in combination with one or more additional active agents. Such intermittent administration allows high doses of the vitamin D compounds to be administered while minimizing or eliminating hypercalcemia.

It is intended to provide an antitumor drug having an excellent therapeutic effect, which is excellent in terms of antitumor effect and safety. There is provided an antibody-drug conjugate in which an antitumor compound represented by the following formula is conjugated to an anti-TROP2 antibody via a linker having a structure represented by the following formula: -L¹-L²-L^P-NH—(CH₂)n¹-L^a-(CH₂)n²-C(═O)— wherein the anti-TROP2 antibody is connected to the terminal of L¹, and the antitumor compound is connected to the carbonyl group of the —(CH₂)n²-C(═O)— moiety with the nitrogen atom of the amino group at position 1 as a connecting position.

As an antitumor drug which is excellent in terms of antitumor effect and safety, there is provided an antibody-drug conjugate in which an antitumor compound represented by the following formula is conjugated to an antibody via a linker having a structure represented by the following formula:

-L¹-L²-L^P-NH—(CH₂)n¹-L^a-L^b-L^c-

wherein the antibody is connected to the terminal of L¹, and the antitumor compound is connected to the terminal of L^c with the nitrogen atom of the amino group at position 1 as a connecting position.

A programmable control system for a crane that senses a hydraulic pressure of the lift mechanism, and controls the movements of the crane apparatus as a function of the magnitude of the hydraulic pressure. As the status conditions of the crane change, sense switches relay such information to a programmable controller and error codes are generated and presented to the operator. The control system can respond to the states of the sense switches and override wireless command inputs to the control system.

The invention provides a method and system of dynamic PIN and dynamic PIN card, the referred dynamic PIN method includes that a group of dynamic PIN is random generated, each dynamic PIN has the character of uniqueness. The dynamic PIN is stored and the corresponding relation between the each dynamic PIN and a coordinate data is established. When in the course of dynamic PIN confirmation: prompting the coordinate data; inputting the PIN corresponding to the coordinate data; judging whether the referred coordinate data is consistent with the dynamic PIN. If they are identical, then the input dynamic PIN passes the security qualification. The cost of this invention lower than the certification qualification, but the security, operationality is between the certification qualification and static PIN qualification, the security guarantee of payment is fulfilled.

A magnetic latching system for connecting two components, the magnetic latching system being comprised of a latch assembly and an anchor bar assembly. More specifically, a latch assembly having a latch pull, which contains a latch magnet, and a latch hook, and an anchor bar assembly having an array of anchor bars riveted to a steel plate. The latch magnet attaches to the steel plate to create a lock-free soft closure. Sliding the latch assembly over an anchor bar will engage a hook portion of the latch hook, creating a secure, locked closure. Pulling up on the latch assembly and sliding the latch assembly away from the anchor bar will unlock the magnetic latching system.

A system and method for ameliorating spinal column anomalies, such as scoliosis, includes bone screws which are to be implanted in the pedicle region(s) of individual to-be-derotated vertebrae and in vertebrae to which balancing forces must be applied as the spinal column is derotated en mass to achieve an over-all correction of the condition. A pedicle screw cluster derotation tool simultaneously engages multiple pedicle screws and transmits rotative forces to multiple vertebrae to effect a whole-spine correction. Precontoured spinal rods are engaged post-derotation to secure the correction.

A device and method to facilitate the coupling of trailer with a socket to a truck with a ball, in which a direction signal is generated by a transmitter on the trailer indicative of the direction the socket is from the ball, and a distance signal returned to a receiver on the truck is timed to determine the distance between the ball and the socket, which signals are used to generate an indication on a display.

As an antitumor drug which is excellent in terms of antitumor effect and safety and has an excellent therapeutic effect, there is provided an antibody-drug conjugate in which an antitumor compound represented by the following formula is conjugated to an anti-HER2 antibody via a linker having a structure represented by the following formula: -L¹-L²-L^P-NH—(CH₂)n¹-L^a-(CH₂)n²—C(═O)— wherein the anti-HER2 antibody is connected to the terminal L¹, and the antitumor compound is connected to the carbonyl group of the —(CH₂)n²—C(═O)— moiety with the nitrogen atom of the amino group at position 1 as the connecting position.

To provide an antitumor drug having excellent therapeutic effect, which is excellent in terms of antitumor effect and safety. Provided is an antibody-drug conjugate in which an antitumor compound represented by the following formula is conjugated to an anti-HER3 antibody via a linker having a structure represented by the formula: -L¹-L²-L^P-NH—(CH₂)n¹-L^a-(CH₂)n²-C(═O)— or -L¹-L²-L^P- (the anti-HER3 antibody is connected to the terminal of L¹, the antitumor compound is connected to the carbonyl group of —(CH₂)n²-C(═O)— moiety or the C terminal of L^P, with the nitrogen atom of the amino group at position 1 as a connecting position).

A tool for abrading a workpiece to smooth the surface thereof. The tool has a shank portion and a working portion. The working portion has a smooth and non-abrading surface, with one or more depressions formed therein. Each depression includes an abrading mechanism. The abrading mechanism does not protrude above the smooth surface of the working portion of the tool. During operation, once the workpiece has been smoothed by removal of the raised areas by the abrading mechanism, the smooth surface of the tool engages the workpiece and further abrasion of the workpiece is prevented.

A handheld work apparatus has an electric motor and a voltage source for operating the motor. A manual actuation element provided on a handle of the apparatus is operated by a user and is provided for activating the motor. The actuation element is connected to a control unit which controls the energy supply from the source to the motor as a function of an operating signal of the actuation element. If the control unit is in a blocking state, the energy supply to the motor is blocked independently of the operating signal of the actuation element. After receiving a control signal, the control unit switches from the blocking state to a standby state to release an energy supply to the motor. The control signal is derived from a combination of an actuation stroke and an actuation time (ΔT_B) of the actuation element. A method for activating the apparatus is also disclosed.