The present invention relates to a control method, system, control device, and storage medium for automatic lane change of a vehicle. The method includes: when the vehicle enters an adaptive cruise acceleration state, obtaining the corresponding first target demand torque T according to the target acceleration 0 and the virtual throttle opening; determine whether the vehicle will perform an automatic lane change according to the virtual throttle opening, the current vehicle speed and the current gear position, and if so, the first target demand torque T according to the shift information 0 Adjust to obtain the second target demand torque T 1 , and the second target demand torque T 1 sent to the engine control unit, if not, the first target demand torque T 0 Sent to the engine control unit. The system corresponds to the method, the control device and the storage medium include a program for executing the method, and the implementation of the present invention can avoid frequent gear shifting during the automatic lane change process of the vehicle.