The invention provides a negative poisson ratio mattress and relates to the field of mattresses. The negative poisson ratio mattress comprises two layers of cushion layers arranged in a spaced mode, and a negative poisson ratio three-dimensional structure arranged between the two cushion layers, negative poisson ratio holes are formed inside at least one of the cushion layers, and the negative poisson ratio holes with different poisson coefficients are formed in the thickness direction of the cushion layers. When the mattress is pressed, the negative poisson ratio three-dimensional structure is contracted inwards, the elastic strength of the mattress is improved, thus the elastic supporting effect is better realized, the body of a user can be effectively supported, it is guaranteed that the structure is still stable and reliable after the mattress is pressed for a long term, meanwhile, due to existence of the negative poisson ratio holes, the smaller the pressure borne by the cushion layers is, the easier compressive deformation is, otherwise, the larger the pressure is, the more difficult compressive deformation is, the user obtains soft supporting of the early stage firstly, subsequent and more powerful elastic supporting can be obtained with increasing of the pressure and the compression amount, finally, double properties of softness and comfort and powerful springback are presented, and the product experience of the user is improved.