The invention discloses a pixel circuit, a driving method, a display panel, and a display device, wherein the pixel circuit includes: a first transistor, a second transistor, a third transistor, a fourth transistor, a fifth transistor, a driving transistor, and a first capacitor and the second capacitor, through the cooperation between each transistor and the capacitor, the present invention at least achieves one of the following beneficial effects: the drive current is equal to the threshold voltage of the drive transistor itself, the voltage drop of the power supply signal, and the voltage across the two ends of the light-emitting element. Regardless, the influence of the above factors is eliminated, thereby effectively improving the problem of uneven light emission of the display device, and improving the uniformity of light emission and the display effect of the display device.