The invention discloses a method for preparing sulfydryl modified ferroferric
oxide /
silicon dioxide
magnetic nanoparticles. The method comprises the following steps that 1, magnetic ferroferric
oxide particles are prepared with trivalent
ferric salt serving as raw materials through a solvothermal method; 2, tetraethoxysilane is adopted as a
silicon source, generated
silicon dioxide wraps the surfaces of the magnetic ferroferric
oxide particles through a
sol-
gel method, and ferroferric oxide /
silicon dioxide magnetic nanoparticles are formed; 3, the ferroferric oxide /
silicon dioxide magnetic nanoparticles are placed in a methylbenzene solution and dispersed evenly to obtain a solution A, dimercaptosuccinate is added to a
dimethyl sulfoxide solution and dispersed evenly to obtain a solution B, the solution A and the solution B are mixed and stirred and react for a period of time, then
solid-liquid separation, cleaning and
drying are carried out, and then the sulfydryl modified ferroferric oxide /
silicon dioxide magnetic nanoparticles are obtained. The magnetic nanoparticles are good in dispersing performance, achieve good stability and
biocompatibility, and has potential application value in the bio-medical field.