39results about How to "Reduce and prevent production" patented technology

An battery-powered electrosurgical instrument includes a blade having a conductor edge portion and insulation layer with geometric shapes and composition that concentrate electrosurgical energy and reduce or eliminate the production of smoke and eschar and reduce tissue damage, thereby providing more efficient application of electrosurgical energy. The more efficient use of electrosurgical energy permits configuring the system to be battery-powered. The system may be portable or configured as a battery-backup powered system.

Methods and compositions useful for subterranean formation treatments, such as hydraulic fracturing treatments and sand control that include porous materials. Such porous materials may be selectively configured porous material particles manufactured and / or treated with selected glazing materials, coating materials and / or penetrating materials to have desired strength and / or apparent density to fit particular downhole conditions for well treating such as hydraulic fracturing treatments and sand control treatments. Porous materials may also be employed in selected combinations to optimize fracture or sand control performance, and / or may be employed as relatively lightweight materials in liquid carbon dioxide-based well treatment systems.

An battery-powered electrosurgical instrument includes a blade having a conductor edge portion and insulation layer with geometric shapes and composition that concentrate electrosurgical energy and reduce or eliminate the production of smoke and eschar and reduce tissue damage, thereby providing more efficient application of electrosurgical energy. The more efficient use of electrosurgical energy permits configuring the system to be battery-powered. The system may be portable or configured as a battery-backup powered system.

An electrosurgical instrument blade includes a body having more than two electrodes with at least two electrodes having alternating current power supplied to them provide a bipolar alternating current configuration and employ a means other than electrode spacing for reducing or preventing accumulation of eschar. The electrodes are separated from each other using electrically insulating materials such that electric current does not flow between at least two of the bipolar alternating current electrodes unless they contact at least one other electrically conductive medium, such as patient tissue. The conductor edge portion and insulation layer each have geometric shapes and composition to reduce or eliminate the production of smoke and eschar and reduce tissue damage. The outer profile of the insulation layer and conductive element are configured to facilitate the flow of electrosurgical decomposition products away from the conductor edge where they are formed.

Methods and compositions useful for subterranean formation treatments, such as hydraulic fracturing treatments and sand control that utilize relatively lightweight and / or substantially neutrally buoyant particulates. Particles that may be employed include particulates of naturally occurring materials that may be optionally strengthened or hardened by exposure to a modifying agent; porous materials including selectively configured porous material particles manufactured and / or treated with selected glazing materials, coating materials and / or penetrating materials; and well treating aggregates composed of an organic lightweight material and a weight modifying agent. The relatively lightweight particulate may be suspended as a substantially neutral buoyant particulate and stored with a carrier fluid as a pumpable slurry.

An electrosurgical blade for use in electrosurgery includes a body having at least one conductive element that is surrounded by an insulation layer except at a conductor edge portion of the conductive element. The profile of the electrosurgical blade is configured to concentrate the flow of electrosurgical energy in a concentration region to facilitate starting or initiating the electrosurgical process. The profile of the electrosurgical blade is further configured to prevent excessive delivery of electrosurgical energy to reduce or eliminate the production of smoke and eschar and reduce tissue damage.

An electrosurgical blade includes a conductive element that is surrounded by an insulation layer except at a conductor edge portion of the conductive element. The conductor edge portion and insulation layer each have unique geometric shapes and composition of the parts to reduce or eliminate the production of smoke and eschar and reduce tissue damage. The outer profile of the insulation layer and conductive element are configured to facilitate the flow of electrosurgical decomposition products away from the conductor edge where they are formed.

An electrosurgical instrument includes a body having at least one conductive element that is surrounded by an insulation layer except at a conductor edge portion of the conductive element. The profile of the electrosurgical instrument is configured to concentrate the flow of electrosurgical energy in a concentration region to facilitate starting or initiating the electrosurgical process. The profile of the electrosurgical instrument is further configured to prevent excessive delivery of electrosurgical energy to reduce or eliminate the production of smoke and eschar and reduce tissue damage.

An electrosurgical instrument includes a conductive element in the form of a needle that is surrounded by an insulation layer except at a conductor tip portion of the conductive element. The conductor tip portion and insulation layer each have unique geometric shapes and composition of the parts to reduce or eliminate the production of smoke and eschar and reduce tissue damage. The electrosurgical needle electrode is configured to concentrate the flow of electrosurgical at the tip region.

An improved electrosurgical instrument includes a body having more than two electrodes with at least two electrodes having alternating current power supplied to them provide a bipolar alternating current configuration and employ a means other than electrode spacing for reducing or preventing accumulation of eschar. The electrodes are separated from each other using electrically insulating materials such that electric current does not flow between at least two of the bipolar alternating current electrodes unless they contact at least one other electrically conductive medium, such as patient tissue. The conductor edge portion and insulation layer each have geometric shapes and composition to reduce or eliminate the production of smoke and eschar and reduce tissue damage. The outer profile of the insulation layer and conductive element are configured to facilitate the flow of electrosurgical decomposition products away from the conductor edge where they are formed.

An electrosurgical instrument is disclosed for simplifying making incisions and other treatments using electrosurgery. The electrosurgical instrument comprises a body having at least one conductive element that is surrounded by an insulation layer except at a conductor edge portion of the conductive element. The conductor edge portion and insulation layer each having unique geometric shapes and composition of the parts to reduce or eliminate the production of smoke and eschar and reduce tissue damage. The outer profile of the insulation layer and conductive element are configured to facilitate the flow of electrosurgical decomposition products away from the conductor edge where they are formed.

The present invention provides recombination based methods for assembling nucleic acids. In certain aspects the present invention provides hierarchical assembly methods for producing genome sized polynucleotide constructs. The methods may be used for assembling large polynucleotide constructs, for synthesizing synthetic genomes, or for introducing a plurality of nucleotide changes throughout the genome of an organism. In another aspect, the invention provides cells having increased genomic stability. For example, cells comprising alterations in at least a substantial portion of the transposons in the genome are provided.

An electrosurgical instrument blade includes a body having more than two electrodes with at least two electrodes having alternating current power supplied to them provide a bipolar alternating current configuration and employ a means other than electrode spacing for reducing or preventing accumulation of eschar. The electrodes are separated from each other using electrically insulating materials such that electric current does not flow between at least two of the bipolar alternating current electrodes unless they contact at least one other electrically conductive medium, such as patient tissue. The conductor edge portion and insulation layer each have geometric shapes and composition to reduce or eliminate the production of smoke and eschar and reduce tissue damage. The outer profile of the insulation layer and conductive element are configured to facilitate the flow of electrosurgical decomposition products away from the conductor edge where they are formed.

Methods and compositions useful for subterranean formation treatments, such as hydraulic fracturing treatments and sand control that include porous materials. Such porous materials may be selectively configured porous material particles manufactured and / or treated with selected glazing materials, coating materials and / or penetrating materials to have desired strength and / or apparent density to fit particular downhole conditions for well treating such as hydraulic fracturing treatments and sand control treatments. Porous materials may also be employed in selected combinations to optimize fracture or sand control performance, and / or may be employed as relatively lightweight materials in liquid carbon dioxide-based well treatment systems.

Administration of a monoamine oxidase inhibitor is useful in the prevention and treatment of muscle dystrophy. Methods and compositions for inhibiting the production of reactive oxygen species in a muscle cell overproducing reactive oxygen species are provided herein.

Methods for treating and / or alleviating acute respiratory distress syndrome in an individual diagnosed with or at risk of developing acute respiratory distress syndrome are disclosed. The methods comprise administering a therapeutically effective amount of a complement inhibitor or a TNF-alpha inhibitor to the individual, wherein the complement inhibitor or the TNF-alpha inhibitor reduces or prevents tissue factor production in alveolar neutrophils, thereby treating the ARDS, or delaying or preventing onset of ARDS.

A method for controlling a transition from an initial polymerization reaction to a target polymerization reaction in a manner that reduces significantly the amount of off-grade product having excessively low density produced during the transition, including steps of: during the transition, maintaining a first one of a concentration ratio and a feed ratio at an at least substantially constant value while implementing process changes in an effort to bring produced polymer into compliance with a target specification set and monitoring (without controlling) the other one of the concentration ratio and the feed ratio to generate first data; and during the transition, determining from the first data whether polymer having excessively low density is likely to be produced during the transition, and upon determining that polymer having excessively low density is likely to be produced during the transition, maintaining during the remaining portion of the transition the other ratio at a value that is at least substantially constant while allowing the first ratio to vary is provided.

A method of fracturing a subterranean formation comprises introducing into the formation at a pressure sufficient to create or enlarge a fracture in the formation a fracturing composition comprising a carrier and a polymeric particulate derived from a cashew nut shell liquid, the polymeric particulate having an apparent specific gravity of less than about 2.4.

An electrosurgical needle includes a body having at least one conductive element in the form of a needle that is surrounded by an insulation layer except at a conductor tip portion of the conductive element. The conductor tip portion and insulation layer each have unique geometric shapes and composition of the parts to reduce or eliminate the production of smoke and eschar and reduce tissue damage. The electrosurgical needle electrode is configured to concentrate the flow of electrosurgical energy at the tip region.

The invention relates to a method for fermentative production, on an industrial scale, of lipid-rich biomass of microalgae of the Chlorella genus having acceptable sensory properties, characterized in that the dissolved oxygen availability in the fermenter is controlled by tracking the respiratory quotient of said microalgae.

A selection system suitable for use in vivo is provided, the system comprising: I) a plurality of first nucleotide sequences encoding a gene product capable of binding to and effecting the cleavage, directly or indirectly, of a nucleotide sequence, or a transcription product thereof; wherein a region of the first nucleotide sequence required for binding to the nucleotide sequence is heterogeneous within the plurality of first nucleotide sequences; and ii) a second nucleotide sequence comprising: (a) a coding region encoding a detectable marker operably linked to sequences required for mRNA stability and / or translation; and (b) a third nucleotide sequence positioned between the coding region and at least one of the sequences required for mRNA stability and / or translation; wherein (a) and (b) are operably linked to a regulatory sequence capable of directing expression of (a) and (b) as a contiguous RNA molecule in a host cell; and wherein the first nucleotide sequence encoding a gene product is capable of binding to and effecting the cleavage, directly or indirectly, of the third nucleotide sequence or a transcription product thereof.

The invention relates to a method for fermentative production, on an industrial scale, of lipid-rich biomass of microalgae of the Chlorella genus having acceptable sensory properties, characterised in that the dissolved oxygen availability in the fermenter is controlled by tracking the respiratory quotient of said microalgae.

An electrosurgical instrument is disclosed for simplifying making incisions and other treatments using electrosurgery. The electrosurgical instrument comprises a body having at least one conductive element that is surrounded by an insulation layer except at a conductor edge portion of the conductive element. The conductor edge portion and insulation layer each having unique geometric shapes and composition of the parts to reduce or eliminate the production of smoke and eschar and reduce tissue damage. The outer profile of the insulation layer and conductive element are configured to facilitate the flow of electrosurgical decomposition products away from the conductor edge where they are formed.

A method for producing steel includes: (a) a step of adding the first group of alloys to molten steel having an amount of dissolved oxygen of 0.0050 mass % or more; (b) a step of, after the step of (a), adding deoxidizer to the molten steel for deoxidation; (c) a step of, after the step of (b), adding the second group of alloys to the deoxidized molten steel; and (d) a step of, after the step of (c), adding REM to the molten steel, wherein amounts of oxygen Ob introduced from the first group of alloys (mass %) and amounts of oxygen Oa introduced from the second group of alloys (mass %) satisfy [Oa≤0.00100], [Ob+Oa≥0.00150], and [Ob / Oa≥2.0], and satisfy a formula [0.05≤REM / T.O≤0.5] after the step of (d).

A method for controlling a transition from an initial polymerization reaction to a target polymerization reaction in a manner that reduces significantly the amount of off-grade product having excessively low density produced during the transition, including steps of: during the transition, maintaining a first one of a concentration ratio and a feed ratio at an at least substantially constant value while implementing process changes in an effort to bring produced polymer into compliance with a target specification set and monitoring (without controlling) the other one of the concentration ratio and the feed ratio to generate first data; and during the transition, determining from the first data whether polymer having excessively low density is likely to be produced during the transition, and upon determining that polymer having excessively low density is likely to be produced during the transition, maintaining during the remaining portion of the transition the other ratio at a value that is at least substantially constant while allowing the first ratio to vary is provided.