Method for preparing mesh-shaped bionic bone porous stent material

A technology of porous scaffold and bionic bone, which is applied in the field of biomedical materials and tissue engineering regenerative medicine, can solve problems such as unsatisfactory practical application effects, excessively large pore structure, and application research limitations, and achieve significant social and economic benefits. Preparation Simple process and broad application prospects
CN102058902BInactive Publication Date: 2013-07-10XI AN JIAOTONG UNIV
2 Cites 0 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
XI AN JIAOTONG UNIV
Publication Date
2013-07-10
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention relates to a method for preparing mesh-shaped bionic bone porous stent material, comprising the following steps: taking a multi-cellular marine animal natural sponge processed by organic acid and inorganic alkali solution as a template, impregnating with sol or water based slurry of hydroxylapatite, 45S5 bioactive glass, beta-tricalcium phosphate or calcium silicate, drying, oxidizing, demoulding and sintering at high temperature, thereby preparing the bone tissue engineering stent material in a mesh-shaped pore structure. The pore structural parameters and degradation performance of a porous stent are controlled by adjusting the solid content in the sol or the slurry, impregnation frequency and parameters in the process of oxidizing and demoulding as well as sintering at high temperature. Pore size of the mesh-shaped porous stent produced by adopting the invention is 100-300Mum, porosity is 68-94%, and the porous stent is highly similar to a natural cancellous bone in the shape and pore size. The product prepared by adopting the invention has the characteristics that bionic degree of the porous structure is high, adaptation to materials is high, process is simple and cost is low and the product has a great application potential in the regeneration repairing technology of hard tissue engineering, such as bone, basibranchial bone and teeth.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention belongs to the technical field of biomedical materials and tissue engineering regenerative medicine, and relates to a preparation method of a bionic porous support material for bone tissue engineering, in particular to a preparation method of a mesh-shaped bionic bone porous support material. Background technique

[0002] Tissue engineering is a new type of regenerative medical technology developed in recent years for the purpose of repairing, maintaining and promoting the shape, structure and function of defective tissues or organs. This technology achieves tissue or organ regeneration and repair by planting seed cells in a three-dimensional porous scaffold material, culturing, proliferating and differentiating in vitro or in vivo, and is expected to replace autologous tissue transplantation, allogeneic / xenogeneic tissue transplantation and Restorative methods such as implants. In tissue engineering technology, the three-dimensional por...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More