33results about How to "Avoid risk of transmission" patented technology

The invention relates to a tissue sealant and a preparation method and application thereof. The sealant mainly comprises hydrophilic raw material, nucleophilic raw material, a marker and physiological thinner, wherein the hydrophilic raw material mainly refers to the derivatives of polyethylene glycol and the nucleophilic raw material mainly refers to polyamino acid. The preparation method includes: physically mixing the hydrophilic raw material, the nucleophilic raw material, the marker and the physiological thinner through a mixing tool, and performing covalent cross-linking to form hydrogel. The tissue sealant has the advantages that the sealant mainly used for sealing small wounds after eye surgery is good in tissue cohesive force and film-forming property, good in biocompatibility, capable of promoting epithelization healing and preventing seepage leakage, simple in preparation method, capable of being quantified to form a stable production line, and good in clinical application value.

The invention relates to a soybean protein isolate-based biomedical adhesive and a preparation method thereof. The method comprises the following steps: firstly, dissolving soybean protein isolate into phosphate buffer; then, adding 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride and N-hydroxysuccinimide; stirring for reacting for 30-60 minutes, and then adding dopamine; continuously stirring for reacting for 10-36 hours; lastly, performing dialysis, centrifugal separation and freeze drying to obtain dopamine-modified soybean protein isolate; during use, the following steps are adopted: dissolving the dopamine-modified soybean protein isolate into the phosphate buffer; then, adding a cross-linking agent and an anti-inflammation anti-bacterial agent; mixing uniformly, and smearing the mixture on a wound; dropwise adding an FeCl3 solution, so that the wound can be bonded firmly within 20-120s. The prepared biomedical adhesive has the characteristics of rapid response and long-acting bonding, can achieve a very good bonding effect in in-vivo and in-vitro wet environments, has high biocompatibility, is fully biodegradable in vivo, and can promote rapid healing of the wound.

The invention provides an acellular dermal matrix guided tissue regeneration membrane material as well as a preparation method and application thereof, and relates to the technical field of medical biological materials. The preparation method provided by the invention comprises the following steps: pretreating, removing an epidermal layer, preparing a loose surface, stabilizing, performing the accellular treatment, washing, and sterilizing. A membrane material prepared by the method provided by the invention adopts fish skin as a raw material and has a three-dimensional space framework structure, and comprises a compact surface formed by a biological substrate membrane and a collagen loose surface formed by a dermal scaffold. By adopting the membrane material provided by the invention, therisk of the existing tissue restoration material in carrying and propagating the human-animal viruses can be avoided, the cell components can be completely removed, the immunogenicity is low, the clearance of the collagen fibers is increased, a corium layer structure is reserved, the tissue compatibility is good, the mechanical shielding effect is good, and the generation of new bones can be facilitated; and when used for restoring and treating the bone deficiency of an oral implantation operation, the material is digestible, and the second operation and the injury of the membrane material topatients can be effectively avoided.

The invention discloses a gradient material for guiding regeneration of periodontal hard and soft tissues, and a preparation method of the gradient material. The gradient material is constructed by combining an electrostatic spinning technology with a biological 3D (three dimensional) technology. A micropore structure of an electrostatic spun fibrous membrane can prevent gingival fibroblasts frommigrating to a root surface to play a mechanical barrier role and facilitate transmission of nutrition and metabolism substances; and individualized repair of alveolar bone can be achieved according to clinical requirements since a structure and a shape of a 3D printing scaffold layer are highly designable. The method is simple and stable in preparation technology, and the gradient material integrates a periodontal guided tissue regeneration membrane and an alveolar bone repair scaffold material and has a potency to achieve clinical customized treatment. The gradient material has a good effectof guiding the repair of the hard and soft tissues in vivo and can be better applied to the synchronous regeneration and repair of the alveolar bone and the periodontal tissues.

The invention discloses a striped rice borer standardized feeding and management method which includes the processes of artificial feed preparation, larva 36-day feeding and adult feeding. The methodfirst suggests 5 days as the period of indoor population egg collection, 4 days as the period of pupa collection and 36 days as the larva feeding period of inoculating single-batch egg masses into a pupation stage. By standardized management of different stage operation processes, a multi-batch overlap loop feeding novel management system is established. The basic requirements of indoor populationlong-term subculture feeding can be met, reproduction can be expanded at any time according to change of test insect dosage, and the preparation period of test insects with different instars and at different stages is greatly shortened. Besides, the method effectively solves the problem of unstable striped rice borer indoor population feeding scale, namely the condition that accidental populationscale rapidly shrinks and even tends to be extinct. The method can be popularized as a striped rice borer indoor artificial feeding technical specification.

The invention relates to a construction site emergency management system. The construction site emergency management system comprises an intelligent robot, an intelligent detection device and a dronedisinfection unit, the intelligent robot is connected with a grade-A tertiary hospital health system, the intelligent robot, the drone disinfection unit and a monitoring group are connected with an administrator computer data terminal and a cloud database, the intelligent robot comprises a robot main body, mechanical arms arranged on the two sides of the robot body, a throat swab sample storage box arranged in the center, a medical high-definition camera, a voice guiding device, a medical material storage box arranged at the lower portion, a daily material storage box, a moving device arrangedat the bottommost portion and a telescopic device arranged at the bottom, wherein the medical high-definition camera and the voice guiding device are arranged at the top of the robot, and the intelligent detection device comprises a body temperature detector, a heart rate detector, a virus nucleic acid detector and an alarm device. The construction site emergency management system is novel in design, high in practicability, high in safety degree, good in timeliness, high in social benefit, good in development prospect and high in intelligent degree.

The invention discloses a method for treating kitchen waste based on an ultrahigh-temperature aerobic composting technology. High temperature generated in the pre-fermentation process at the earlier stage of thermophilic bacteria compost fermentation is used for sterilization, and then the thermophilic bacteria are subjected to tank turning treatment, so that the kitchen waste with viruses is turned into an organic fertilizer in a safer, more efficient and more environment-friendly way. The operation involves the following raw materials in parts by weight: 26-52 parts of kitchen waste, 20-40 parts of sludge, 35-70 parts of leaves and 120-240 parts of sludge bacteria. Compared with an existing kitchen waste treatment method, the method saves cost, is convenient to operate and is suitable for nationwide popularization.

The invention discloses a preparation method of degradable antibacterial hemostatic hydrogel capable of promoting diabetic wound repair. The hydrogel with a three-dimensional network structure is prepared from dopamine (DA) grafted oxidized natural polysaccharide and jellyfish collagen (JC) through a cross-linking agent. The hydrogel prepared by the invention not only has excellent tissue adhesion performance, antibacterial performance and hemostasis performance, but also has very strong water retention capacity, provides a moist environment for wound healing of diabetes mellitus, and accelerates wound healing. The invention has the advantages that: 1, the prepared degradable hydrogel with antibacterial and hemostatic functions for repairing the diabetic wound surface does not need to be additionally added with antibiotics when being used for treating the diabetic wound surface, so that the generation of drug resistance is avoided; 2, the used collagen is derived from plankton in an aquatic environment, and compared with animal-derived collagen, outbreak of zoonosis (mad cattle disease, porcine brucellosis, inhalable anthrax and the like) and some potential virus transmission risks are avoided;

The invention provides a hidden automatic-cleaning intelligent toilet. The hidden automatic-cleaning intelligent toilet comprises a toilet body external machine, a toilet unit and a sewage dischargingunit, the toilet body external machine is embedded into a concaved wall and internally provided with a pressurizing water tank, a steam unit, a cleaning unit and an intelligent control unit, the toilet unit is provided with a connecting rotating shaft which is connected with the inner side of the toilet body external machine, the pressurizing water tank is communicated with the toilet unit through a shaft pipeline, the rotating shaft is connected with the control unit, the toilet unit is arranged in the concaved position of the toilet body external machine and installed above the sewage discharging unit, the toilet unit is opened after the shaft is rotated by 90 degrees and then extends out, and the toilet unit rotates to be closed to be flush with the wall perpendicularly; the sewage discharging unit and the toilet unit are closed and the connected through a butt joint opening. The intelligent toilet is a hidden toilet, systematic optimization is conducted on the mode that accordingto a traditional hidden water tank toilet, a hidden water tank is installed first, and then a toilet body is installed, the change from two-stage installation to one-time installation at the late stage is safer and more convenient, the toilet is hidden in a wall or is made upright to be installed on the wall, in this way, the space for installation and usage is saved, and a bathroom is convenientto manage and neater. The function of automatic cleaning is realized, during storage, a seat is cleaned, and therefore sanitation and cleanliness are guaranteed when the seat is used again; an intelligent dredging device is further arranged, a gas auxiliary dredging function is further set, and therefore no blocking occurs.

The invention provides a bionic medical fibroblast with a sequence of SEQ ID NO:1. On the one hand, the invention provides a preparation method for preparing a protein fragment of the fibroblast. Theprotein fragment is 160-324-locus amino acid of a scallop byssus protein with a sequence of SEQ ID NO:1, and the sequence of the protein fragment is SEQ ID NO:2. The protein prepared into the fibroblast is prepared by virtue of a genetic engineering method from the material source, is low in cost and environment-friendly and can be produced in a large scale. A protein-base material is derived fromocean scallop byssus, is formed through polymerization in a similar seawater environment and has good adaptability and stability to a humidity environment. The bionic medical fibroblast has relatively good development prospects in the medical material field. According to a marine organism derived material, the transmission risk of terrestrial biological diseases is avoided in the aspect of the biological safety of materials, and an examination result shows that the material has no cytotoxicity and has good biocompatibility.

The invention provides a continuous and rapid disposable blood collecting needle automatic blood collecting device. The automatic blood collecting device comprises a base and a cover body, wherein oneend of the base is provided with a protruding connecting piece; the connecting piece is movably connected with a rack through a connecting shaft; a circle of limiting holes are formed in the rack; the rack is of a hollow structure, and a hollow inner cavity of the rack is a blood collecting needle arrangement cavity; a plurality of disposable blood collecting needles are sequentially arranged inthe blood collecting needle arrangement cavity; a spring pushing plate is arranged in the blood collecting needle arrangement cavity and pushes the disposable blood collecting needles to a feeding device; a feeding round hole is formed in the head of the rack; the feeding device is arranged in the feeding round hole; a stepping motor is connected in a center hole of the feeding device; an ejectionpush rod and a discharge push rod are arranged at the upper part of the feeding device; a blood sampling hole and a discharging hole are formed in the lower portion of the ejection push rod and the lower portion of the discharging push rod respectively; a clamping device is arranged at the other end of the base to clamp fingers; and a sensor is arranged below the clamping device.

The invention discloses a non-contact keyboard capacitance sensor and a key position input method. The non-contact keyboard capacitance sensor comprises a power supply circuit, a capacitance sensor, acapacitance-to-digital conversion circuit, a control module, a state feedback control circuit, an indicator and a communication circuit. The capacitance sensor comprises a first electrode arranged onthe outer side of the periphery of the key position, a second electrode arranged on the periphery of the key position and a third electrode arranged in the center of the key position, wherein any electrode is at least a double-bond position, and the third electrode sinks by 0.8-3.5 mm compared with the second electrode; the three-dimensional position of the finger on the keyboard is determined bydetecting the self-capacitance of each electrode, and a three-state response of the finger pointing to the key position is provided and inputted through the feedback control circuit. The invention provides a low-cost and mature CDC chip technology which is reasonable in structural design and high in resolution, effectively resists various interferences and makes full use of capacitance detection,and a commercial non-contact input solution which can be popularized and promoted is provided for sanitation sensitivity.

The invention relates to the field of biomedical materials, in particular to a fish-skin decellularized dermal matrix scaffold as well as a preparation method and application thereof. The method comprises the following steps: pretreating fish skin to obtain dermal-layer skin grafts; and separately carrying out virus inactivation, decoloration, degreasing, immunogenicity removal, cross-linking, freeze-drying shaping, cutting and sterilization on the dermal-layer skin grafts. According to the method disclosed by the invention, the damage to a collagen structure of the fish-skin dermal matrix scaffold is reduced to the maximum, collagenous fibers are arranged in order, pores are uniform and regular, the hydrophilicity is strong, rapid vascularization can be realized, and good mechanical properties, good biocompatibility and good tissue induction capability are achieved. The material is widely applied to replacement and repair treatment of dermis defects.

The invention discloses a treatment process of hospital sewage containing highly pathogenic viruses, and relates to the technical field of sewage treatment. The treatment process specifically comprises the following process steps: S1, enabling sewage to sequentially pass through a grid channel and an adjusting tank, and adding a bactericide into the adjusting tank to obtain pretreated sewage; S2,filtering the pretreated sewage through an ultrafiltration membrane pool to obtain filtered water and concentrated sewage; S3, sequentially introducing the filtered water into a hydrolysis acidification tank, an aerobic tank and an MBR membrane tank for treatment so as to obtain purified water subjected to sterilization treatment; enabling the concentrated water to flow back to the adjusting tankto be mixed with the inlet water of the grid channel, and continuously performing sterilization treatment through the adjusting tank. The preparation method has the advantage of reducing the secondaryinfection risk of the highly pathogenic viruses.

The invention provides a method for preparing an organic fertilizer by using penicillin mushroom dreg compost, and relates to the technical field of organic fertilizers. The organic fertilizer is prepared from the following raw materials in parts by weight: 30-70 parts of penicillin mushroom dregs, 15-35 parts of cow dung, 15-35 parts of straws and 0.1-0.3 part of a compost fermentation inoculant, wherein the content of penicillin in the penicillin mushroom dregs is less than or equal to 0.1 mg / L. The organic fertilizer prepared by the invention is high in content of organic matter, balanced in content of nutrient substances such as nitrogen, phosphorus and potassium and high in total amount, particularly, the content of nitrogen element is remarkably increased, sufficient nutrition can be provided for plants, and good growth of the plants can be promoted under the condition of low fertilizing amount. Meanwhile, the organic fertilizer is subjected to innocent treatment, penicillin is removed, generation and propagation risks of drug-resistant genes can be avoided, and the organic fertilizer is safe to use. The organic fertilizer prepared by the method provided by the invention overcomes the defect of drug-resistant gene transmission risk in preparation of the organic fertilizer from antibiotic mushroom dreg compost in the prior art, and has good application prospects.

The invention discloses a medicine and food for resisting new corona-virus infection and application. The medicine or food contains lysozyme or a combination containing the lysozyme. The lysozyme or the combination thereof can be used for preparing medicines for resisting new corona-virus infection and preventing or treating diseases or symptoms related to new corona-virus or food for assisting in resisting new corona-virus infection and assisting in preventing or treating diseases or symptoms related to new corona-virus. The lysozyme or the combination thereof can effectively inhibit cell injury and inflammatory response caused by the new corona-virus, relieve symptoms of a digestive system, improve airway obstruction, expiration volume reduction and intestinal barrier functions, and have good prevention and treatment effects on new corona-virus infection or related diseases or symptoms thereof; in addition, in-vivo removal of the virus is accelerated, in-vivo new corona-virus nucleic acid detection negative conversion speed is accelerated, the disease course of a patient is shortened, transmission of the new corona-virus is effectively prevented and reduced, and important social benefits and good application prospects are achieved.

The invention relates to a method for preparing mesh-shaped bionic bone porous stent material, comprising the following steps: taking a multi-cellular marine animal natural sponge processed by organic acid and inorganic alkali solution as a template, impregnating with sol or water based slurry of hydroxylapatite, 45S5 bioactive glass, beta-tricalcium phosphate or calcium silicate, drying, oxidizing, demoulding and sintering at high temperature, thereby preparing the bone tissue engineering stent material in a mesh-shaped pore structure. The pore structural parameters and degradation performance of a porous stent are controlled by adjusting the solid content in the sol or the slurry, impregnation frequency and parameters in the process of oxidizing and demoulding as well as sintering at high temperature. Pore size of the mesh-shaped porous stent produced by adopting the invention is 100-300Mum, porosity is 68-94%, and the porous stent is highly similar to a natural cancellous bone in the shape and pore size. The product prepared by adopting the invention has the characteristics that bionic degree of the porous structure is high, adaptation to materials is high, process is simple and cost is low and the product has a great application potential in the regeneration repairing technology of hard tissue engineering, such as bone, basibranchial bone and teeth.

The invention relates to a construction site emergency management system, including an intelligent robot, an intelligent detection device and a drone disinfection unit. The intelligent robot is connected to the health system of a tertiary hospital. The terminal is connected to the cloud database; the intelligent robot includes a robot main body, mechanical arms on both sides of the robot main body, a throat swab sample storage box in the center, a medical high-definition camera and a voice guidance device on the top of the robot, and a The lower medical material storage box, the daily material storage box and the bottommost mobile device are located at the bottom telescopic device; the intelligent detection device includes a body temperature detector, a heart rate detector, a virus nucleic acid detector, and an alarm device; through the present invention , the construction site emergency management system is novel in design, strong in practicability, high in safety, good in timeliness, high in social benefits, good in development prospects, and high in intelligence.

The invention discloses a standardized feeding and management method for Chilo suppressalis, which comprises artificial feed preparation, 36-day feeding of larvae and feeding processes of adults. The present invention proposes for the first time that 5 days are used as the cycle for collecting worm eggs for indoor populations, 4 days is used as the cycle for collecting pupae, and 36 days are used as the larva rearing cycle for a single batch of egg masses to be inoculated to the pupation stage. Through the standardized management of the operation process of different insect states, a new management system of multi-batch and overlapping cycle feeding has been established. The invention can not only meet the basic needs of long-term subculture of indoor populations, but also can expand and reproduce at any time according to the change of the number of test insects, which greatly shortens the preparation period of test insects of different ages and different states. In addition, the present invention effectively solves the problem of unstable breeding scale of the indoor population of the stem borer, that is, the sporadic population size shrinks rapidly or even tends to become extinct, and can be popularized as a technical specification for the indoor artificial breeding of the stem borer.

A sealing agent hydrogel, and a kit and preparation method therefor. The sealing agent hydrogel is prepared from the following raw material components: an electrophilic raw material as a first component; a nucleophilic material as a second component; a bioadhesive material as a third component, comprising 4-arm-PEG-DA; a physiological diluent as a fourth component, containing an alkaline buffer having a pH value of 7.5 to 12.5 and an acidic buffer having a pH value of 2.0 to 6.5. The sealing agent hydrogel features the addition of a chemically modified polyethylene glycol macromolecule monomer on the basis of a conventional two-component hydrogel, so that during use, a hydrogel which has a certain adhesion force is rapidly generated in situ after being mixed. The generated hydrogel features not only excellent biocompatibility, bioadhesion, biodegradability, and degradation performance adjustability, but also significantly shortened gelation time and significant improvements in important indicators such as gel content and swelling rate; and the degradation speed may be adjusted according to the requirements of an application scenario.

The invention relates to a soybean protein isolate-based biomedical adhesive and a preparation method thereof. The method comprises the following steps: firstly, dissolving soybean protein isolate into phosphate buffer; then, adding 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride and N-hydroxysuccinimide; stirring for reacting for 30-60 minutes, and then adding dopamine; continuously stirring for reacting for 10-36 hours; lastly, performing dialysis, centrifugal separation and freeze drying to obtain dopamine-modified soybean protein isolate; during use, the following steps are adopted: dissolving the dopamine-modified soybean protein isolate into the phosphate buffer; then, adding a cross-linking agent and an anti-inflammation anti-bacterial agent; mixing uniformly, and smearing the mixture on a wound; dropwise adding an FeCl3 solution, so that the wound can be bonded firmly within 20-120s. The prepared biomedical adhesive has the characteristics of rapid response and long-acting bonding, can achieve a very good bonding effect in in-vivo and in-vitro wet environments, has high biocompatibility, is fully biodegradable in vivo, and can promote rapid healing of the wound.

The invention provides a tax place body temperature abnormity early warning method, a device and a system. The method comprises steps: when it is sensed that the taxpayer enters the tax place, measuring the body temperature value of the taxpayer; judging whether the body temperature value exceeds a preset abnormal body temperature threshold value or not; when the body temperature value exceeds theabnormal body temperature threshold value, generating early warning information indicating that the body temperature of the taxpayer is abnormal; judging whether real-name information of the taxpayeris stored in a to-be-referenced tax information base or not, wherein the real-name information comprises a first contact way of the taxpayer; if yes, determining a first contact way of the taxpayer;obtaining a second contact way of at least one current responsible person in the tax place; and sending the early warning information to the taxpayer and the at least one current responsible person through the first contact way and the second contact way. According to the scheme, body temperature abnormity early warning can be carried out more effectively.

The invention provides an antigen diluent and an immunodeficiency virus detection kit, the antigen diluent is mainly composed of a PBS buffer solution, calf serum and a protective agent, the protective agent comprises dimethyl diacetoxysilane, Ectoin and a synergistic protective agent, the synergistic protective agent is prepared from any one of erdosteine, thiomersalate, S-allyl mercaptocysteine and mercaptopyridoxine or a mixture of more of erdosteine, thiomersalate, S-allyl mercaptocysteine and mercaptopyridoxine. According to the antigen diluent, the protective agent capable of enabling the antigen and the antibody to have relatively high activity is added, and the types of the protective agent are screened and reasonably proportioned and mixed, so that after the antigen diluent is adopted, the stability and the accuracy of an immunological detection device are remarkably improved, and the antigen diluent is worthy of wide popularization and application.

The invention provides an acellular dermal matrix-guided tissue regeneration membrane material and its preparation method and application, and relates to the technical field of medical biomaterials. The preparation method of the present invention comprises the following steps: pretreatment, removing the epidermis, preparing a loose surface, stabilizing, decellularizing, washing and sterilizing; the membrane material prepared by the method of the present invention uses fish skin as a raw material and has a three-dimensional space frame structure, including a dense surface composed of a biological basement membrane and a loose collagen surface composed of a dermal scaffold. The membrane material of the present invention avoids the risk of carrying and disseminating zoonotic viruses in the existing tissue repair materials, completely removes cell components, has low immunogenicity, increases the gap between collagen fibers, retains the structure of the dermis, and maintains tissue phase Good capacity, not only has a good mechanical barrier effect but also is conducive to the formation of new bone; when used in the repair of bone defects in oral implant surgery, the material can be absorbed, effectively avoiding the secondary operation and the damage to the patient.

The application discloses a vaccination vehicle and its roof folding canopy, including a flexible umbrella cloth; a support frame assembly for supporting the flexible umbrella cloth and driving the folding and unfolding of the flexible umbrella cloth; and the support frame assembly A rotating shaft connected to one end of the rotating shaft; the support frame assembly includes, fixedly connected with the rotating shaft, a rotating skeleton that drives the movable side of the flexible umbrella cloth to rotate with the rotating shaft; movably connected with the rotating shaft, the flexible The fixed frame to which the fixed side of the umbrella cloth is connected. Compared with the prior art, the vaccination vehicle and its roof folding canopy provided by the present application can quickly arrange vaccination points, have high flexibility, reduce the labor intensity of medical staff, and accelerate the efficiency of vaccination.

The invention discloses a vaccination vehicle and a vehicle roof folding tent thereof. The vehicle roof folding tent comprises flexible umbrella cloth; a supporting frame assembly which is used for supporting the flexible umbrella cloth and driving the flexible umbrella cloth to be folded and unfolded; a rotating shaft which is connected with one end of the supporting frame assembly; the supporting frame assembly comprises a rotating framework which is fixedly connected with the rotating shaft and drives the movable side of the flexible umbrella cloth to rotate along with the rotating shaft; and a fixed framework which is movably connected with the rotating shaft and is used for connecting the fixed side of the flexible umbrella cloth. Compared with the prior art, the vaccination vehicle and the vehicle roof folding tent thereof have the advantages that vaccination points can be quickly arranged, the flexibility is high, the labor intensity of medical staff is reduced, and the vaccination efficiency is improved.

The invention relates to a gel, a complete set of raw materials and applications thereof. The gel is obtained by in-situ cross-linking after blending the first solution and the second solution. The first component contained in the first solution is an aldehyde-modified polysaccharide, and the second component contained in the second solution is composed of a hydrazide group. Molecule, hydrazide-modified polysaccharide composition. The kit consists of a first component and a second component. The gel of the present invention is suitable for tissue engineering applications such as vitreous body replacement gel, ocular surface sealant, and fundus sealant.