ghlim2 protein and its gene and its application in improving cotton fiber quality
A cotton fiber and protein technology, applied in the field of genetic engineering
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Embodiment 1
[0048] Embodiment 1, the cloning of its coding gene of cotton GhLIM2 protein
[0049] 1. Cloning of the gene encoding the cotton GhLIM2 protein
[0050] Analysis of transgenic cotton with silk fibroin light chain gene from upland cotton R15 (Gossypium hirsutum, Shangguan Xiaoxia, Wang Lingjian, Li Yane, etc.) at the elongation stage 12 days after flowering (12DPA). Acta Crops, 2007, 33(5): 697 -702; the public can obtain from the Institute of Microbiology, Chinese Academy of Sciences) isolated a cDNA encoding LIM protein family gene from the fiber, named the gene GhLIM2, and its nucleotide base is sequence 1 in the sequence table, the gene is open for reading The frame (ORF) is the 104th to 676th nucleotides from the 5' end of sequence 1 in the sequence listing. The protein encoded by this gene is named GhLIM2, and the amino acid sequence of the protein is sequence 2 in the sequence listing, and sequence 2 in the sequence listing Consists of 190 amino acid residues.
[0051]...
Embodiment 2
[0054] Example 2, construction and functional identification of transgenic GhLIM2 cotton
[0055] 1. Construction of transgenic GhLIM2 cotton
[0056] 1. Construction of recombinant expression vector
[0057] RNA was extracted from upland cotton R15 (Gossypium hirsutum) fibers. The cDNA obtained by reverse transcription was used as a template, 5'-GATCGGATCCATGGCATTTGCAGGAACAAC-3' was used as an upstream primer (with a BamHI restriction site) and 5'-GCTACCGCGGGAGCTCAGATTCAGCAGCAACTTCAGTTCCA-3' was used as a downstream primer (with a SacII and SacI restriction site ) to obtain a 570bp PCR product (after sequencing, sequence 1 with sequence listing from 104th to 673rd nucleotides at the 5' end).
[0058] Construction of pPZP-GhLIM2: Digest the above PCR product with BamHI and SacI, and combine the obtained restriction product with the pPZP vector (HajdukiewiczP, SvabZ, MaligaP (1994) The small, versatilePZPfamilyofAgrobacteriumbinaryvectorsforplant transformation. PlantMolBiol2...
Embodiment 3
[0089] Example 3, Analysis of subcellular localization of GhLIM2
[0090] The pPZP-GFP-GhLIM2 plasmid was introduced into Agrobacterium EHA105 (Biovector, catalog number: 197343) to obtain recombinant bacteria. The extracted plasmid was sent for sequencing. The plasmid was pPZP-GFP-GhLIM2, and the recombinant bacteria containing the plasmid was named pPZP-GFP-GhLIM2 / EHA105.
[0091] The pPZP-GFP-GhLIM2 / EHA105 and tobacco suspension cell BY-2 (NagataT, NemotoY, HasezawaS (1992) TobaccoBY-2 cell line as the 'HeLa' cell in the cell biology of higher plants. IntRevCytol132: 1-30; public available from the Institute of Microbiology, Chinese Academy of Sciences) were mixed statically Placed for 4 hours, 28°C, 110rpm and co-cultivated for 28-36 hours, and screened on kanamycin medium to obtain a cell line transfected with pPZP-GFP-GhLIM2. The BY-2 cells transfected with pPZP-GFP-GhLIM2 were observed with a confocal fluorescence microscope, and the excitation wavelength of GFP was 48...
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