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Oral care product containing hawthorn seed alcohol extracts and having helicobacter pylori resistant function

An anti-Helicobacter pylori and oral care technology, applied in the field of daily chemicals, can solve the problems of reduced treatment effect, recurrent disease, loss, etc., and achieve the effects of killing Helicobacter pylori, preventing oral transmission, and maintaining stable dosage and ingredients.

Active Publication Date: 2015-11-04
杭州华胄生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The disadvantages of the prior art are: 1. Kill a large number of beneficial bacteria, which easily leads to repeated outbreaks of the disease. 2. The taking of large doses of multiple antibiotics increases the drug resistance of Helicobacter pylori, and the drug resistance of the bacteria makes the original effective antibiotics less effective. The treatment effect is reduced or lost, which increases the difficulty of treatment and medical costs for patients
Although there are some Chinese herbal health care toothpastes on the market, the antibacterial effect is not ideal enough, especially it does not have the effect of killing Helicobacter pylori

Method used

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  • Oral care product containing hawthorn seed alcohol extracts and having helicobacter pylori resistant function
  • Oral care product containing hawthorn seed alcohol extracts and having helicobacter pylori resistant function
  • Oral care product containing hawthorn seed alcohol extracts and having helicobacter pylori resistant function

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] The toothpaste with anti-helicobacter pylori effect containing hawthorn ribohol extraction is composed of the following components in parts by weight: 90 parts of calcium hydrogen phosphate, 25 parts of water, 7 parts of sorbitol, 3 parts of hydrated silica, polyethylene glycol 3 parts of -8, 4 parts of propylene glycol, 2 parts of sodium lauryl sulfate, 3 parts of cellulose gum, 3 parts of hydroxyethyl cellulose, 3 parts of essence, 3 parts of sodium benzoate, 3 parts of sodium saccharin, ethanol extract of hawthorn kernel 3 copies.

[0027] Wherein, hawthorn kernel ethanol extract is prepared by the following method:

[0028] 1) Take the clean dried hawthorn core and crush it to obtain hawthorn core powder;

[0029] 2) According to the ratio of material to liquid (g / ml) of 1:10, add 1000mL of 70% ethanol to 100g of hawthorn core powder prepared in step 1), and reflux and extract at 80°C for 4 hours to obtain the extract;

[0030] 3) Filtrate the extract with filter ...

Embodiment 2

[0035] The mouthwash with anti-Helicobacter pylori effect containing hawthorn kernel alcohol extract is composed of the following components in parts by weight: 95 parts of water, 15 parts of sorbitol, 7 parts of propylene glycol, 8 parts of xylitol, PEG-400 polymer 8 parts of ethylene glycol, 3 parts of dimethyl glycyrrhizinate, 3 parts of sodium benzoate, 2 parts of essence, 3 parts of hawthorn kernel ethanol extract.

[0036] The preparation method of hawthorn kernel ethanol extract is the same as in Example 1.

Embodiment 3

[0038]The chewing gum with anti-Helicobacter pylori effect containing hawthorn kernel alcohol extract is composed of the following components in parts by weight: 35 parts of xylitol, 25 parts of gum base, 17 parts of sorbitol, 17 parts of maltitol liquid, D- 8 parts of mannitol, 170 parts of citric acid, 110 parts of phospholipids, 35 parts of aspartame, 35 parts of essence, and 3 parts of hawthorn kernel ethanol extract.

[0039] The preparation method of hawthorn kernel ethanol extract is the same as in Example 1.

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Abstract

The invention discloses an oral care product containing hawthorn seed alcohol extracts and having a helicobacter pylori resistant function. The oral care product is characterized by comprising the hawthorn seed alcohol extracts. The traditional Chinese medicine oral care product is provided, a medicine extraction method is simple, dosage and ingredient are stable, and the product can directly go deep into an oral cavity. The product can not cause disturbance to the environment in the oral cavity after long-term use and is free of side effects. The effects of killing helicobacter pylori and effectively preventing helicobacter pylori from oral transmission are achieved besides the aims, similar to those of oral care products such as Chinese herbal medicine health care toothpaste, of eliminating ozostomia, treating dental ulcer and resisting common oral pathogens to diminish inflammation.

Description

technical field [0001] The invention belongs to the technical field of daily chemicals, and in particular relates to an oral care product containing hawthorn kernel ethanol extract and having the effect of resisting Helicobacter pylori. Background technique [0002] Helicobacter pylori, English name Helicobacter pylori, referred to as Hp. Helicobacter pylori is a highly infectious pathogenic bacteria. In 1983, Australian scholars Barry J.Marshall and Robin Warren J.Robin Warren first isolated and detected Helicobacter pylori in gastric mucosal biopsies of gastritis patients. In 1989, Australian scholar Krajden detected HP from the dental plaque of the oral teeth of patients with gastritis, and confirmed that it was the same as Hp in the stomach from the molecular level. Hp is an orally transmitted infectious disease, and oral Hp is an important reservoir of gastric Hp. The damage of Helicobacter pylori to human health is significant: it is the first carcinogen that induce...

Claims

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Application Information

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IPC IPC(8): A61K8/97A61K36/734A61K9/46A61K9/12A61Q11/00A61P1/02A61P31/04A23G4/12A23G3/48
Inventor 严杰林世恩葛玉梅
Owner 杭州华胄生物科技有限公司
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