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Antibacterial medical coated non-woven fabric and preparation method thereof

A non-woven and coating technology, applied in pharmaceutical formulations, pharmaceutical sciences, fiber types, etc., can solve the problems of incomplete wound dressing, waste of drug dressings, easy torn wounds, etc. secondary tear, reducing the risk of infection

Active Publication Date: 2021-07-13
普宁市康特伦实业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] As a commonly used medical device, non-woven fabrics are widely used in disposable masks, lab coats, wound dressings, etc. At present, the non-woven fabrics used for wound dressings on the market only reduce blood loss and stop bleeding by compressing blood vessels. , and the main component of blood is protein. After the non-woven fabric absorbs blood, if it is not replaced in time, it will easily cause the growth of bacteria and cause further infection of the wound. However, frequent replacement of non-woven fabrics will cause waste of medical dressings, and replacement The process is also very troublesome, especially if there is no professional around to help replace the non-woven fabric, it will easily lead to incomplete wound dressing, increasing the risk of wound infection and tearing
[0003] Secondly, after the non-woven fabric absorbs blood, the blood adheres the wound and the non-woven fabric together, and it is easy to tear the wound when replacing the non-woven fabric, causing secondary tearing of the wound and slowing down the wound healing process; traditional non-woven fabrics The tensile strength of the cloth is also relatively poor, and it is easy to break with a little effort. Therefore, people urgently need a non-woven fabric with strong antibacterial effect, high tensile strength, not easy to break, and can promote wound healing. Coated nonwovens for medical use caused by wounds

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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  • Antibacterial medical coated non-woven fabric and preparation method thereof
  • Antibacterial medical coated non-woven fabric and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] (1) Preparation of non-woven fabric:

[0054] A. Preparation of modified crystal should: mix the nano-zinc oxide whiskers, nano-titanium dioxide crystals, mix well, add a silane coupling agent, adjusting the pH of 4, and continuing to stir 30 min, resulting in modified crystal must;

[0055] B. Preparation of nonwoven fabric: N, N-dimethylformamide is added to the spinning liquid to stir mix, increase the rotational speed to 1100R / min and add modified crystal, electrostatic spinning to obtain a modified yarn, The modified yarn is made into non-woven fabric a;

[0056] C. Preparation of non-woven fabric:

[0057] a) Soak the nonwoven fabric in ethanol in ethanol, under 20 ° C, add a sodium hydroxide solution, continued to be stirred for 10 min, and then dried to obtain a nonwoven fabric B;

[0058] b) Place the sodium hydroxide in the chloroacetic acid solution to stir well, then add acrylic acid, dibenylketone stir well, adjust the pH of 6, then add nonwoven fabric a soak...

Embodiment 2

[0076] (1) Preparation of non-woven fabric:

[0077] A. Preparation modified crystal should: mix the nano-zinc oxide whiskers, nano-titanium dioxide crystals, mixed into the ethanol solution, add the silane coupling agent, adjust the pH of 5, and continue to stir 40 min, resulting in modified crystal must;

[0078] B. Preparation of nonwoven fabric: N, N-dimethylformamide is added to the spinning liquid and mix, increase the rotational speed to 1200R / min and add modified crystal, electrospinning to obtain a modified yarn, The modified yarn is made into non-woven fabric a;

[0079] C. Preparation of non-woven fabric:

[0080] a) Soak the non-woven fabric for 20 min in ethanol, under 24 ° C, add sodium hydroxide solution, continued to stir 15 min, remove the drying, to obtain a nonwoven fabric B;

[0081] b) Place the sodium hydroxide in the chloroacetic acid solution to stir well, then add acrylic acid, dibenzone stirring, adjust the pH of 7, then add nonwoven fabric a soaking 1....

Embodiment 3

[0099] (1) Preparation of non-woven fabric:

[0100] A. Preparation of modified crystal should: mix the nano-zinc oxide whiskers, nano-titanium dioxide crystals, mix well, add a silane coupling agent, adjusting the pH of 6, continued to stir 60 min, resulting in modified crystal must;

[0101] B. Preparation of non-woven fabric: N, N-dimethylformamide is added to the spinning liquid and mix, increase the rotational speed to 1300 r / min and add modified crystal, electrostatic spinning to obtain a modified yarn, The modified yarn is made into non-woven fabric a;

[0102] C. Preparation of non-woven fabric:

[0103] a) Soaked the nonwoven fabric in ethanol to 25 min, under 28 ° C, add a sodium hydroxide solution, continued to stir 20 min, and dry it to obtain a nonwoven fabric B;

[0104] b) Place the sodium hydroxide in the chloroacetic acid solution to stir well, then add acrylic acid, dibenylketone stir well, adjust the pH of 8, then add nonwoven fabric a soaking 2H, remove, ethan...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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Abstract

The invention discloses an antibacterial medical coated non-woven fabric and a preparation method thereof. First, the nano-zinc oxide whisker and the nano-titanium dioxide whisker are modified by using a silane coupling agent, and the modified whisker is mixed into the spinning stock solution Spinning and fabricating nonwoven substrates; loading sustainable Ag on graphene oxide + Obtain modified graphene oxide, join modified graphene oxide, lauric anhydride in coating A and be coated on the lower surface of non-woven fabric substrate; Antibacterial microcapsule, porous starch are mixed in coating B and coated Cover the upper surface of the non-woven fabric substrate, and obtain an antibacterial coated non-woven fabric through ultraviolet light irradiation; the present invention prepares an antibacterial medical coating through the synergistic effect of coating A, coating B, and non-woven fabric substrate Non-woven fabrics have excellent antibacterial properties, the strongest hemostatic effect, high tensile breaking strength, and are soluble in water, so they have very broad application prospects.

Description

Technical field [0001] The present invention relates to the field of nonwoven fabric technology, in particular to antibacterial medical coating nonwovens and preparation methods thereof. Background technique [0002] The non-woven fabric is used as a common medical device, which is widely used in disposable masks, laboratory, wound bags, etc. At present, the non-woven fabric for wounds on the market is only to reduce blood loss by oppressing blood vessels. And the main component of the blood is protein. After absorbing blood, it is not timely replacement to cause breeding of bacteria to cause further infection of the wound, but frequent replacement non-woven fabrics will cause waste of drug dressing, and replace The process is also very troublesome, especially if you don't have a professionals to help replace non-woven fabrics, it is easy to cause incomplete wounds to dress up, increase wound infections and tear risks. [0003] Secondly, the non-woven fabric is adhering to the wo...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L15/18A61L15/42A61L15/46A61L15/28A61L15/20A61L15/40A61L15/62D06N3/00D04H1/728D01F1/10D01F6/92D01F6/94D01F6/46D06M11/38D06M10/08D06M101/32D06M101/30D06M101/20
CPCA61L15/18A61L15/42A61L15/46A61L15/28A61L15/20A61L15/425A61L15/40A61L15/62D06N3/0011D06N3/0063D06N3/0061D04H1/728D01F1/10D01F6/92D01F6/94D01F6/46D06M11/38D06M10/08A61L2400/12A61L2300/104A61L2300/102A61L2300/404A61L2300/232A61L2300/412A61L2300/418A61L2300/30A61L2400/04D06N2211/18D06M2101/32D06M2101/30D06M2101/20C08L3/02C08L5/08
Inventor 王宏澜
Owner 普宁市康特伦实业有限公司
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