The invention relates to a medicament for preventing and treating bee infectious disease chalk disease, the components of which are 30g of silver flower, 10g of coptis, 15g of sophora, 15g of banlangen, 30g of rhubarb, 10g of rhubarb, 6g of licorice, 10g of centipede, 50g of centipede, Aescin 15g, Guanzhong 50g, and Promethamine 5000g. This formula is a basic prescription. According to the health status of the bee colony, the dosage of individual medicines can be adjusted appropriately. Baofengjian does not need to be specially prepared, it is mixed according to the basic formula, and is formulated into a compound medicine through grinding, soaking, filtering, heating and other methods - Baofengjian, through changing the box of the sick bee colony, and spraying it with spray when changing the spleen This compound medicine prevents and treats bee diseases. The compound medicament of the invention is simple to make, easy to use, low in price, rapid and thorough in sterilization, safe to bee products, has no adverse effects on humans, livestock, crops, etc., and meets all ecological and environmental protection requirements. It is an ideal fungicide for bee breeding.