One or more embodiments of this specification provide an airway management navigation method and system. By establishing an interactively operable digital anatomical model, and by measuring the patient's anatomical data and evaluating imaging data, the anatomical feature data of the patient's head, neck and airway are obtained. Input it into the interactive operation digital anatomical model, and adjust the model in real time. By establishing the digital model of the airway tool, the position and posture parameters of the patient's head and neck and airway anatomical model and the position and posture of the airway tool are tracked and sensed, and the head and neck and airway anatomical model and airway tool model for graphic fusion, and real-time output of airway and airway tool images, breaking through the forbidden area of traditional surgical navigation technology in airway management application, easy to use and low cost, making airway management operations no longer necessary Relying on the glottic field of vision, it can effectively reduce the number of blind detection operations, improve the success rate of ventilation and intubation and the safety level of patients, and has good social benefits and market value.