Gemini nicotinate quaternary ammonium salt and method for making same
A quaternary ammonium salt and nicotinic acid technology, applied in chemical instruments and methods, organic chemistry, transportation and packaging, etc., can solve the problems of decreased use effect, low bactericidal concentration, high water solubility, etc., and achieves weak foaming, high The effect of surface activity and strong sustained release ability
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Example Embodiment
[0032] Example 1
[0033] Preparation of brominated di-N-alkylnicotinic acid ethylene glycol / diethylene glycol / triethylene glycol ester (EQn-m-n)
[0034] Synthesis of EQ16-2-16
[0035] Add niacin and thionyl chloride with a molar ratio of 1:5 into the reaction flask, stir and reflux, and the NaOH solution absorbs the tail gas. After 4 hours of reaction, cooling, spin-drying excess thionyl chloride under reduced pressure, white needle-like crystals were obtained. Dry chloroform is used as the solvent, and triethylene glycol with a molar ratio of 1:2 to niacin is slowly dripped. The NaOH solution absorbs the tail gas and refluxes for 10 hours. After cooling, spin dry the solvent, add proper amount of water to dissolve, use saturated Na 2 CO 3 Adjust the pH of the aqueous solution to weakly alkaline, separate the organic phase, extract the aqueous phase with ethyl acetate 2-3 times, combine the organic phases, spin dry and pass through the column with ethyl acetate. The resulting p...
Example Embodiment
[0043] Example 2
[0044] Structural characterization of brominated di-N-alkylnicotinic acid ethylene glycol / diethylene glycol / triethylene glycol ester (EQn-m-n)
[0045] Structural characterization of EQ16-0-16
[0046]
[0047] Refer to Figure 1. Figure 1 is the hydrogen spectrum of EQ16-0-16. According to the spectrum, the chemical shift and related parameters of EQ16-0-16 are listed in Table 1 below:
[0048] Table 1EQ16-0-16 1 HNMR parameters
[0049] Absorption peak
[0050] It can be seen from Table 1: Groups 1, 2, 3, and 4 are hydrogen on the pyridine ring, 5 are methylene hydrogens directly connected to nitrogen, and 6 are methylene hydrogens directly connected to oxygen on the ester group. 7 , Group 8 is the methylene hydrogen on the long chain alkane, and group 9 is the methyl hydrogen on the end of the long chain alkane. The total number of hydrogen atoms is half of the number of hydrogen atoms in the target product molecule, and it is inferred that the mol...
Example Embodiment
[0066] Example 3
[0067] Study on the surface activity of brominated di-N-alkylnicotinic acid ethylene glycol / diethylene glycol / triethylene glycol ester (EQn-m-n)
[0068] The surface active agent to be measured is formulated into a series of aqueous solutions of a certain concentration with double distilled water, and the surface tension of the aqueous solution of the surface active agent is measured by the ring method at 20°C. The measurement results are shown in Figure 4 and Table 4.
[0069] It can be seen from Figure 4 that with the addition of this series of surfactants, the surface tension of the water drops sharply, the concentration increases, the surface tension drops slowly, and finally stabilizes. The alkyl chain increases and the surface activity increases.
[0070] Table 4 cmc and γ of several surfactants cmc And C 20
[0071] substance
[0072] EQ10-0-10
[0073] Note: C 20 It represents the concentration of surfactant needed to reduce the surf...
PUM
Property | Measurement | Unit |
---|---|---|
Melting point | aaaaa | aaaaa |
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.
© 2023 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap