Medical apparatus carrying gene and/or medicament and preparation method thereof

A medical device and drug technology, applied in the field of medical devices carrying genes and/or drugs and their preparation, can solve problems such as easy to be washed away by blood flow, limited amount of genes, loss of therapeutic genes, etc.
CN101502696BActive Publication Date: 2012-07-11LEPU MEDICAL TECH (BEIJING) CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
LEPU MEDICAL TECH (BEIJING) CO LTD
Publication Date
2012-07-11

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Abstract

The invention relates to a medical apparatus carrying gene and / or medicament and a preparation method thereof. The medical apparatus employs the electrostatic adhesion and / or micropore adhesion principle, the surface of the medical apparatus body is directly coated and / or fixed with active medicament and / or therapeutic genes, the invention has the advantages that various therapeutic genes and medicament are compounded on the same platform and the advantages of plural therapeutic genes and medicament are combined, thus radically solving the problems of restenosis and endothelialization delay. The preparation method is simple, the fixing effects of gene and medicament are good, the introduction of matrix carrier loaded with medicament and genes can be saved, the reaction hazard of restenosis and phlegmonosis caused by implantation can be reduced, and the cure effect is better than that of the current implanted medical apparatus.
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Description

technical field

[0001] The invention relates to the field of medical devices, in particular to a medical device carrying genes and / or drugs and a preparation method thereof. Background technique

[0002] In 1987, since Sigwart et al. used intravascular metal stents for coronary arteries for the first time, it has provided a good way for the treatment of vascular occlusion diseases. However, in-stent restenosis has always been the main reason affecting the efficacy of percutaneous coronary intervention (PCI). With the listing of Johnson & Johnson's Cypher rapamycin drug stent in 2004 and Boston Scientific's Taxus paclitaxel drug stent in 2005, drug-eluting stents have reduced the in-stent restenosis rate from 30% in the bare metal stent era to less than 10%.

[0003] However, with the in-depth study of drug stents, the continuous expansion of the scope of application, and the gradual increase in the number of accumulated cases, people should become more rational in their use...

Claims

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