Method for separating and purifying glufosinate-ammonium

Abstract

The invention discloses a method for separating and purifying glufosinate-ammonium. The method comprises the steps: 1, diluting glufosinate-ammonium crude liquid into a solution with mass fraction of 10-80% by water; then, carrying out pretreatment on the solution by a 20-100mu m filter bag to remove mechanical impurities which are possibly caused in the glufosinate-ammonium synthesis process; and 2, adjusting the pH of the solution to be within the range of 3-9, and enabling the solution to enter a chromatographic column filled with strong acid type cation exchange resin at the temperature of 0-100 DEG C, with water as an eluting agent, and respectively collecting eluant and residual liquid, wherein the eluant is a glufosinate-ammonium solution, and the residual liquid is an inorganic salt solution. After the technical scheme is adopted, the method for separating and purifying the glufosinate-ammonium has the beneficial effects that the method is high in selectivity, degree of separation, product concentration and purity and simple in technology; the feed of the whole technology comprises raw materials and pure water, and the discharge of the whole technology comprises the glufosinate-ammonium and the inorganic salt, so that other wastes are not produced.

Description

technical field [0001] The invention relates to the field of glufosinate-ammonium production, in particular to a separation and purification method for glufosinate-ammonium. Background technique [0002] Glufosinate ammonium (Glufosinate ammonium) is developed and produced by the German company Hoechst, and its chemical formula is C 5 h 12 NO 4 P, with a formula weight of 181.127, is easily soluble in water, not easily soluble in organic solvents, stable to light, and is an inhibitor of glutamine synthesis. Glufosinate-ammonium is a highly efficient, low-toxic, non-selective (killing) contact organophosphorus herbicide with partial systemic action. Glufosinate-ammonium has the advantages of low toxicity, relatively safe, easy to degrade in soil, safe to crops, small drift, wide herbicidal spectrum, high activity, low dosage, low environmental pressure, rapid weed killing, etc., and can prevent or quickly kill More than 100 annual or perennial dicotyledonous broadleaf or ...

AI Technical Summary

Problems solved by technology

[0004] In the chemical synthesis method, a large amount of inorganic salts and organic impurities will be produced along with the synthesis process of glufosinate-ammonium, which is difficult to separate by ordinary methods. Generally, the difference in solubility of glufosinate-ammonium and inorganic salts in organic solvents is used to realize the synthesis of synthetic products. Separation, but this method consumes solvent and may cause solvent residues and bring unsafe factors to the operation; "Hebei Chemical Industry" Volume 30 No. 6 "Glufosinate (Basta) Ion Exchange Lipid Purification Technology" mentioned the use of 201× 7 Strongly basic anion exchange resin adsorbs inorganic impurities, then elutes with HCl, and crystallizes with ethanol to obtain a product with a purity of more than 99%, but the yield of this method is low, the loss of glufosinate-ammonium is large, and the production wastewater pollutes the environment; in addition , the Chinese invention patent with the publication number CN102127110A discloses "A Method for Separation and Purification of Glufosinate-ammonium Solution", which discloses a process for the separation and purification of glufosinate-ammonium by using a nanofiltration membrane and an electrodialysis membrane combination process, which can obtain glufosinate-ammonium Ammonium phosphine mass fraction 15-30%, inorganic salt mass fraction 0.05-0.5% glufosinate-ammonium solution and glufosinate-ammonium solution mass fraction 0.01-0.1%, inorganic salt mass fraction 3-7% inorganic salt solution, this method does not It needs acid and alkali, which can protect the environment well, but this method also has the following defects: when the aqueous solution of high-concentration glufosinate-ammonium and inorganic salt circulates in the membrane, its escape rate will increase greatly, and the product purity is about 95%. In the water system, the product concentration cannot be too high in the electrodialysis process, so the recovered by-product inorganic salts, product glufosinate-ammonium and its early crude product have high steam consumption when dissolving, and the industrial operability is poor

In summary, the existing glufosinate-ammonium separation and purification methods have the disadvantages of large consumption of organic solvent, high operating cost, low concentration, complicated operation, and serious environmental pollution.