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Hydrophilic and oleophilic gel eye pad with eye fatigue relieving function and eye care function and preparation method thereof

A technology that relieves visual fatigue and has dual effects. It is applied in the direction of medical preparations containing active ingredients, active ingredients of hydroxyl compounds, active ingredients of anhydride/acid/halide, etc. It can solve the problem of reducing the ability of the skin to communicate with the outside world and enhancing the barrier of the epidermal stratum corneum Effects, skin surface temperature rise, etc., to achieve the effect of improving the persistence of vision and simple reactions, promoting eye microcirculation, and promoting metabolism

Active Publication Date: 2016-06-15
北京乳凝创智生物技术研发中心(有限合伙)
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0014] 2. The amount of drug ingredients added cannot satisfy a certain "dose-effect ratio" relationship
[0015] 3. Poor air permeability: The traditional gel film has the problem of poor air permeability, especially oil gel. This poor air permeability is easy to cause skin discomfort, and at the same time makes the skin surface temperature rise sharply, giving people a "stuffy" feeling. At the same time, it can cause severe dehydration in the deep layer of the skin, and form "sweat retention" on the surface of the skin, causing serious damage to the surface layer of the skin. Although the hydrogel reduces the temperature of the skin surface, shrinks the pores, reduces heat dissipation, and finally reduces skin surface sensitivity. To a certain extent, this solves the discomfort caused by poor air permeability and makes the skin feel comfortable, but to a certain extent, it affects the activity of skin cells, enhances the barrier function of the epidermal stratum corneum, and reduces the material exchange between the skin and the outside world. The ability to affect the transdermal absorption of pharmaceutical ingredients and nutrients

Method used

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  • Hydrophilic and oleophilic gel eye pad with eye fatigue relieving function and eye care function and preparation method thereof
  • Hydrophilic and oleophilic gel eye pad with eye fatigue relieving function and eye care function and preparation method thereof
  • Hydrophilic and oleophilic gel eye pad with eye fatigue relieving function and eye care function and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] In this experiment, a styrene-isoprene-styrene block copolymer with a combined styrene content of 15% was used as a skeleton material, liquid paraffin was used as a softener, and C5 petroleum resin was used as a tackifier to prepare an amphiphilic gel material. as follows:

[0054] Amphiphilic Gel Matrix Formulation:

[0055] component name

Styrene and Isoprene Block Copolymer

C5 petroleum resin

liquid paraffin

hyaluronic acid

Sodium polyacrylate

Other functional additives

ContentWt / %

25.7

16.8

44.5

2

5.4

5.6

[0056] Other functional additives include: inorganic fillers such as calcium carbonate, talcum powder, zinc oxide, etc. to adjust the shape of the amphiphilic gel material.

[0057] The amphiphilic gel matrix preparation method is as follows:

[0058] 1) Add "styrene-isoprene-styrene block copolymer" and liquid paraffin into a reaction kettle with a stirring paddle, heat and stir at a certain ...

Embodiment 2

[0064] In this experiment, a combination of styrene-isoprene-styrene block copolymer and styrene-isoprene diblock copolymer with a styrene content of 15% was used as the skeleton material, and low molecular weight polyisobutylene with a molecular weight of 400 Amphiphilic gel materials were prepared as softeners, hydrogenated rosin glycerides and polyisobutylenes of different molecular weights as tackifiers, as follows:

[0065] Amphiphilic gel matrix material formulation:

[0066] components

name

Styrene-isoprene-styrene block copolymer

with styrene-isoprene diblock copolymer

Rosin

Glycerin

ester

Judgment

Butene

transparent

Hyaluronic acid

sodium

methyl cellulose

Vitamin Sodium

polypropylene

enoic acid

sodium

other

Auxiliary

7 --> content

Wt / %

18.3

8.3

56.6

2.5

2.7

6.7

4.9

[0067] Other functional additives include: inorganic fillers such as calcium c...

Embodiment 3

[0075] In this experiment, a drug prescription of parental gel eye patch was prepared for the purpose of relieving visual fatigue. The specific ingredients and preparation process are as follows:

[0076] The pharmaceutical ingredients of the parent gel eye patch include: less than 10% taurine, less than 10% lutein, less than 5.00% grape seed extract, less than 5.00% hydrolyzed proanthocyanidin, less than 5.00% bilberry fruit extract, olive oil Less than 60.00%, beta-carotene less than 5.00%, retinyl palmitate less than 5.00%, vitamin E less than 5.00%, rutin less than 5.00%, ascorbyl palmitate less than 5.00%, peppermint extract less than 5.00%, transparent Sodium hyaluronate is less than 5.00%.

[0077] Preparation process: Weigh each component according to the above ratio, add mint extract to olive fruit oil and stir to dissolve, add retinyl palmitate, β-carotene, and vitamin E to it, mix and stir evenly, and then add taurine Acid, lutein, grape seed extract, hydrolyzed pr...

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Abstract

The invention relates to a hydrophilic and oleophilic gel eye pad with the eye fatigue relieving function and the eye care function such as black eye relieving and radiation protection and a preparation method thereof. The eye pad comprises hydrophilic and oleophilic gel and medicine components, specifically, the hydrophilic and oleophilic gel and the medicine components are evenly mixed, then back lining cloth is coated with the mixture, the other side of a hydrophilic and oleophilic gel coating is covered with a release film / paper, and then the hydrophilic and oleophilic gel coating is cut into a certain shape through a die, and the eye pad is prepared. The eye pad is small in irritation to skin and does not cause skin allergy, medicine stability is good when the eye pad is preserved for a long time, lipophobic and waterborne nutrient ingredients needed by eyes can be added at the same time, it can be kept that various functional components or nutrient ingredients are in the dissolution state and can be adsorbed easily, and particularly no preservative or traditional surfactant needs to be added in the preparation process of the pad.

Description

technical field [0001] The invention relates to a parental gel eye patch with the functions of relieving visual fatigue, removing dark circles, preventing radiation and other eye skin care functions and a preparation method thereof. Background technique [0002] Visual fatigue, also known as eye fatigue, is a term used to describe a series of symptoms related to excessive use of the eyes, and its causes are complex and diverse. Modern medicine believes that the main causes of visual fatigue are as follows: 1) Increased eye load at close range; 2) Refractive errors; 3) Bad eye habits, such as improper eye distance when reading, watching TV, etc. Improper posture, too dark light, continuous eye use, etc.; 4) Diet and nutrition factors. Improper diet leads to malnutrition of the whole body and eyes, and is also one of the factors that induce visual fatigue. [0003] In the information society, computers, TVs, game consoles and other video display terminals (VDT) have penetrat...

Claims

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Application Information

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IPC IPC(8): A61K36/87A61K9/70A61P27/02A61P17/00A61K31/015A61K31/047A61K31/07A61K31/185A61K31/353A61K31/355A61K31/375A61K31/045
CPCA61K9/7053A61K9/7076A61K31/015A61K31/045A61K31/047A61K31/07A61K31/185A61K31/353A61K31/355A61K31/375A61K36/534A61K36/87A61K2300/00
Inventor 侯玉庆刘彦宏陶几中马丹徐健梅侯天歌
Owner 北京乳凝创智生物技术研发中心(有限合伙)
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