Calcium-phosphorus-silicon biological ceramic coating and preparation method and application thereof

Abstract

The invention discloses a calcium-phosphorus-silicon biological ceramic coating and a preparation method and application thereof. After magnesium and alloy of magnesium are put in a calcium-phosphorus electrolyte for powered-on electrolysis for a set time, a sample containing a calcium-phosphorus coating is put in a silicon salt electrolyte for powered-on electrolysis, and the target biological ceramic coating is obtained; and the calcium-phosphorus electrolyte is prepared by adding calcium salt and (NaPO3)6 into a basic electrolyte, and the silicon salt electrolyte is prepared by adding silicate into the basic electrolyte. A compact layer is connected with a basal body, the compact layer and the basal body are tightly combined, and the mechanical property of the basal body can be improved; in addition, pores barely exist in the compact layer, body fluid can be prevented from flowing to the surface of the basal body to make contact with the basal body, metal ions generated after the basal body is corroded also can be prevented from being diffused to the human body, toxicity is reduced, and biocompatibility is effectively improved; and a surface layer is a porous loose layer, combination of an implant and a bone can be effectively improved in the presence of micro-pores, growth of adherence bone tissue of bone cells can be effectively improved, and the biological activity of the coating can be improved.

Description

technical field [0001] The invention belongs to the technical field of materials, and in particular relates to a calcium-phosphorus-silicon bioceramic coating and a preparation method and application thereof. Background technique [0002] At present, artificial bone defect repair and fracture fixation materials in clinical application mainly include medical metal materials, medical bioinorganic materials or bioceramics, medical polymer materials, and medical composite materials composed of the above three materials. Inorganic active ceramics have excellent performance, but their strength is high, their toughness is poor, their elastic modulus is too high, they are prone to brittle fracture, and they are prone to fatigue failure in the physiological environment in the body, so they cannot be directly applied to fracture repair of bearing parts alone. Polymer materials have poor mechanical properties such as hardness and strength, and are not suitable for fracture repair in be...

AI Technical Summary

Problems solved by technology

Although these traditional metal hard tissue repair materials have various excellent properties, they also have many shortcomings, and these shortcomings are almost all determined by the basic properties of their matrix, and it is difficult to make up for it by external means. Limitations include: (1) May release toxic metal ions or particles (Cr 6+ ,V 2+ , Ni 2+ etc.), causing side effects such as inflammation, allergies, tissue damage and even canceration, leading to implant failure; (2) Because its elastic modulus cannot match well with natural bone, it is easy to cause "stress shielding effect", making the stress shielding area Bone remodeling occurs in the bones in the body, which reduces bone density and strength, and secondary fractures are prone to occur after bone plate removal; (3) They play a role of mechanical fixation in the body and cannot be degraded spontaneously in the human body. They are implanted as hard tissue repair When the material is used, after the human tissue is completely healed, a second operation is often required to remove the implant, which not only increases the medical cost, but also easily causes complications during the operation, which brings more pain to the patient

The biological materials prepared by the existing micro-arc oxidation technology generally have problems such as poor electrolyte stability, low biological activity, rapid coating degradation, and easy introduction of toxic ions during the preparation process, which may cause infection.

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