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Composition for treating hormone-dependent dermatitis

A technology for dependent dermatitis and a composition, applied in the field of biomedicine, can solve the problems of strong side effects, inconspicuous, easy to form drug resistance effects, etc., and achieve the effects of no toxic side effects and promoting metabolism

Inactive Publication Date: 2017-04-26
BENGT I SAMUELSSON INST OF LIFE SCI CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] In order to solve the shortcomings of existing hormone-dependent dermatitis treatment products such as incomplete treatment, easy to repeat, strong side effects, easy to form drug resistance, or ineffective effects, the present invention proposes a composition for treating hormone-dependent dermatitis, including Mussel Soft Tissue Extract, Trypsin, Comfrey Extract, and Purslane Extract

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Example 1: The preparation method of mussel soft tissue extract.

[0037] Take mussels and remove their shells, collect 300 g of soft tissue, divide them into three parts, add 100 ml of the acidic solution in Table 1 below with a content of 0.3%, homogenate for 10 minutes, and centrifuge to obtain the supernatant, which is the mussel soft tissue extract.

[0038] The protein content and pH value in the supernatant were determined, and the protein content was determined by the Coomassie brilliant blue method.

[0039] Table 1

[0040] example acid solution protein content pH value 1 citric acid 2.6mg / ml 4.5 2 Acetic acid 3.5mg / ml 3.2 3 perchloric acid 3.0mg / ml 1.0

Embodiment 2

[0041] Embodiment 2: A composition mask of mussel soft tissue extract, trypsin, comfrey extract and purslane extract.

[0042] The composition in this example is composed of the following proportions by weight: mussel soft tissue extract 10mg, trypsin 10mg, comfrey extract 15mg and purslane extract 15mg, vitamin B3: 5mg, vitamin B2: 3mg, vitamin E: 15mg, L-vitamin C: 16mg, green tea extract 15mg, add deionized water to fully dissolve to form a mask liquid. Soak the mask paper into the mask liquid to absorb the solution, apply it on the face, and take off the mask after 15-20 minutes.

[0043] Collect 12 volunteers to participate in the test, use the composition mask of mussel soft tissue extract, trypsin, comfrey extract and purslane extract, apply it once a day, 10 days as a course of treatment, return visit and record within 1 month recurrence.

[0044] Criteria for judging curative effect: Curative effect observation indicators include skin lesions (erythema, papules, acn...

Embodiment 3

[0054] Embodiment 3: a composition mask of mussel soft tissue extract, trypsin, comfrey extract and purslane extract.

[0055] The composition in this example is composed of the following proportions by weight: mussel soft tissue extract 50mg, trypsin 30mg, comfrey extract 25mg and purslane extract 25mg, vitamin B3: 60mg, vitamin B2: 15mg, vitamin E: 30mg, L-vitamin C: 30mg, green tea extract 25mg, add deionized water to fully dissolve to form a mask liquid. Soak the mask paper into the mask liquid to absorb the solution, apply it on the face, and take off the mask after 15-20 minutes.

[0056] Collect 14 volunteers to participate in the test, use the composition mask of mussel soft tissue extract, trypsin, comfrey extract and purslane extract, apply it once a day, 10 days as a course of treatment, return visit and record within 1 month recurrence.

[0057] Criteria for judging curative effect: Curative effect observation indicators include skin lesions (erythema, papules, a...

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Abstract

The invention relates to a composition for treating hormone-dependent dermatitis. The composition comprises mussel soft tissue extract, trypsin, Lithospermum erythrorhizon extract and purslane extract, and also optionally comprises other carriers. The composition has anti-inflammation, anti-allergy, restoration and flesh engendering effects, and has a good treatment effect on the hormone-dependent dermatitis through adjusting the immunity of skins and promoting metabolism of skin cells, the above formula contains no glucocorticoid substances or antibiotics and can be used for a long term without generating dependence, and the composition is also suitable for acnes, acneiform dermatitis, various eczemas, acute and chronic dermatitis, mite dermatitis, and fungus induced psoriasis, porrigo, tinea corporis and manus and tinea pedis, has no toxic or side effects, and has high safety and large cure rate when clinically used.

Description

technical field [0001] The invention relates to the technical field of biomedicine, more specifically, to a composition for treating hormone-dependent dermatitis. Background technique [0002] Hormone-dependent dermatitis is dermatitis caused by long-term and repeated improper use of external corticosteroids. The primary skin lesions disappear after topical glucocorticoids are used, but inflammatory lesions reappear after discontinuation. Repeated use of glucocorticoids is required to control symptoms and gradually An aggravated form of dermatitis. [0003] There are two major causes of hormone-dependent dermatitis: the first is hormone-dependent dermatitis caused by long-term abuse of therapeutic drugs in patients with chronic skin diseases. Patients pursue the rapid onset of drugs when treating facial skin diseases, which leads to facial glucocorticoid dependence. The occurrence of dermatitis is on the rise, which is a relatively traditional cause of the disease; the seco...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/48A61P17/00A61K36/30A61K35/618A61K31/455A61K31/525A61K31/355A61K31/375A61K36/82
CPCA61K35/618A61K31/355A61K31/375A61K31/455A61K31/525A61K36/185A61K36/30A61K36/82A61K38/4826C12Y304/21004
Inventor 高敏
Owner BENGT I SAMUELSSON INST OF LIFE SCI CO LTD
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