Preparation method of medical titanium alloy surface bio-piezoelectric composite coating

A piezoelectric composite and titanium alloy technology, which is applied in the field of surface modification of biomedical materials, can solve the problems of poor binding force between bioactive coatings and substrates, low surface bioactivity, etc., to achieve good combination, good adhesion and value-added, The effect of accelerating bone repair

Active Publication Date: 2018-05-29
XIAN UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0010] The purpose of the present invention is to provide a method for preparing bio-piezoelectric composite coatings on the surface of medical titaniu...

Method used

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  • Preparation method of medical titanium alloy surface bio-piezoelectric composite coating
  • Preparation method of medical titanium alloy surface bio-piezoelectric composite coating

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Experimental program
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Effect test

Embodiment 1

[0050] Place the pretreated titanium matrix sample in a stainless steel tank containing electrolyte, use the titanium sample as the anode, and the stainless steel tank as the cathode, adopt pulsed DC voltage, the voltage is 200V, the pulse frequency is 700Hz, and the duty cycle is 10 %, the oxidation time is 4min, and the electrolyte temperature is 60°C. The electrolyte is composed of deionized water as the solvent, disodium edetate with a concentration of 0.05mol / L as the solute, calcium acetate with a concentration of 0.01mol / L, and sodium dihydrogen phosphate with a concentration of 0.05mol / L. become;

[0051] Add 50% of the total volume of the reaction kettle into the reaction kettle with a concentration of 0.1mol / L barium hydroxide aqueous solution, place the titanium sample after the micro-arc oxidation treatment in the hydrothermal reaction kettle, and then at a temperature of 140°C, Keep warm for 6 hours;

[0052] The sample processed in the above steps is subjected ...

Embodiment 2

[0055] Place the pretreated titanium matrix sample in a stainless steel tank containing electrolyte, use the titanium sample as the anode, and the stainless steel tank as the cathode, adopt pulsed DC voltage, the voltage is 500V, the pulse frequency is 300Hz, and the duty cycle is 20 %, the oxidation time is 8min, and the electrolyte temperature is 60°C. The electrolyte is composed of deionized water as the solvent, disodium edetate with a concentration of 0.1mol / L as the solute, calcium acetate with a concentration of 0.1mol / L, and sodium dihydrogen phosphate with a concentration of 0.07mol / L. become;

[0056] Add 70% of the total volume of the reaction kettle into the reaction kettle with a concentration of 0.2mol / L barium hydroxide aqueous solution, place the titanium sample after the micro-arc oxidation treatment in the hydrothermal reaction kettle, and then at a temperature of 180°C, Keep warm for 8 hours;

[0057] The sample processed by the above steps is subjected to...

Embodiment 3

[0060] Place the pretreated titanium matrix sample in a stainless steel tank containing electrolyte, use the titanium sample as the anode, and the stainless steel tank as the cathode, adopt pulsed DC voltage, the voltage is 400V, the pulse frequency is 500Hz, and the duty cycle is 30 %, the oxidation time is 10min, and the electrolyte temperature is 60°C. The electrolyte is composed of deionized water as the solvent, disodium edetate with a concentration of 0.2mol / L as the solute, calcium acetate with a concentration of 0.15mol / L, and sodium dihydrogen phosphate with a concentration of 0.3mol / L. become;

[0061] Add 0.3 mol / L barium hydroxide aqueous solution with a concentration of 0.3 mol / L to the reaction kettle, place the titanium sample after the micro-arc oxidation treatment in the hydrothermal reaction kettle, and then at a temperature of 200 ° C, Keep warm for 10 hours;

[0062] The sample processed by the above steps is subjected to polarization treatment in air med...

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Abstract

The invention discloses a preparation method for a medical titanium alloy surface bio-piezoelectric composite coating. The preparation method comprises the steps that: firstly, a micro-arc oxidation technology is used for generating an inner dense and superficial porous titanium dioxide coating in situ on the surface of a titanium alloy substrate, then a hydrothermal chemistry method is adopted toreact on the titanium dioxide coating in-situ to produce a barium titanate coating, and finally holes of the surface of the polarized coating are filled, that is, a composite coating with bio-piezoelectric characteristics is formed on the surface of the medical titanium alloy. The inner layer of the coating prepared by the method is compact, has good combination with the substrate, has high stability, and can effectively prevent dissolution of harmful metal ions into body fluid; the surperficial porous barium titanate coating can generate a piezoelectric effect, promote local blood circulation, and further accelerate repair of bone; the pores are filled with substances conducive to growth of early bone tissues or antibacterial drugs, at the same time, the rough surface is conducive to cell adhesion and proliferation so that metal materials can have good biocompatibility and biological activity.

Description

technical field [0001] The invention belongs to the technical field of surface modification of biomedical materials, and relates to a method for preparing a biological piezoelectric composite coating on the surface of a medical titanium alloy. Background technique [0002] Medical titanium alloys are widely used in the field of medical implants because of their high strength, low elastic modulus, non-magnetic properties, excellent chemical stability and good biocompatibility. However, there is a big difference between medical titanium alloy and bone tissue in terms of composition and structure. After being implanted into the human body, it is only a simple mechanical fit with bone tissue, and cannot form a strong chemical bond, which is easy to cause loosening and falling off of the implant. . Therefore, it is very necessary to modify the surface of the titanium alloy. The surface modification can not only retain the excellent properties of the titanium alloy itself, but al...

Claims

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Application Information

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IPC IPC(8): A61L27/56A61L27/06A61L27/30A61L27/32A61L27/54A61L27/50C25D11/26
CPCA61L27/06A61L27/30A61L27/306A61L27/32A61L27/50A61L27/54A61L27/56A61L2300/104A61L2300/112A61L2300/232A61L2300/404A61L2300/412A61L2430/02C25D11/026C25D11/26
Inventor 汤玉斐田朴赵康吴聪
Owner XIAN UNIV OF TECH
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