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A stabilization coating technique for enteric feed biological vitamins

A vitamin and enteric-soluble technology, which is applied in the field of stable coating technology of enteric-coated biological vitamins for feed, can solve the problems of death, long-term stability without liquid package stabilization technology, etc., and achieve the effect of long storage time and high activity

Inactive Publication Date: 2019-03-05
北京农博微生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The yeast existing in the market cannot tolerate high temperature granulation during pellet processing and almost all die
Therefore, the application is very limited
[0008] However, the nano-scale multi-dimensionality of the current process of vitamins does not have a professional liquid coating stabilization technology to maintain the long-term stability of the entire liquid

Method used

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  • A stabilization coating technique for enteric feed biological vitamins
  • A stabilization coating technique for enteric feed biological vitamins
  • A stabilization coating technique for enteric feed biological vitamins

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Screening of lactic acid bacteria culture medium. Including components A, B, C and D, wherein the component A is a mixture of one or more of glucose, sucrose, corn starch, and soybean meal; the component B is peptone, yeast extract, yeast extract One or more mixtures in powder, beef extract, malt extract, described component C is, ferric sulfate, calcium carbonate, ferric chloride, potassium dihydrogen phosphate, dipotassium hydrogen phosphate, magnesium sulfate, sodium chloride One or more mixtures; the components are one or more mixtures of biotin, vitamin B2, vitamin A, vitamin C, and the culture medium of the above-mentioned A, B, C, D combination is at 115 ℃ Sterilize for 50 min and cool to room temperature.

[0034] The lactic acid bacteria (eg, Enterococcus faecalis) screened from animal intestines or feces are inserted into the above-mentioned medium for 18-25 hours at 36°C, and the lactic acid bacteria liquid is centrifuged at 10,000 r / min to obtain a viable b...

Embodiment 2

[0040] The yeast (such as Saccharomyces cerevisiae) preserved in the laboratory was inserted into the medium in Example 1 and cultivated at 30-40°C for 18-25 hours, and the yeast fermentation broth was centrifuged at 10,000 r / min to obtain viable bacteria. Concentration of 10 11 -10 12 Lactic acid fermented concentrated milk.

[0041] Biological multi-dimensional granulation

[0042] In the fermented milk of 10 parts by weight, add fermented milk, the glycerol of glycerol weight ratio 10:1 successively and stir, then add the gelatin solution of 8% (W / V) pH4.0-4.5 (solid content and lactic acid fermented milk) The weight ratio is (6:3), the emulsification is uniform, and the protective agent solution with a mass fraction of 10% (the solid content of the solution is mixed according to the mass ratio of fermented milk: skimmed milk powder: sodium glutamate: lactose 60:36:1:6) Evenly) emulsification 30min, obtain the emulsion of fermented milk.In above-mentioned emulsion, add t...

Embodiment 3

[0046] The lactic acid bacteria (such as Lactobacillus johnsonii) screened from animal intestines or feces are inserted into the medium in Example 1 and cultured at 30-40°C for 18-25 hours. Under the condition of / min, the concentration of viable bacteria obtained by centrifugation was 10 11 -10 12 Lactic acid fermented concentrated milk.

[0047] Biological multi-dimensional granulation

[0048] 10 parts by weight of fermented milk were successively added with fermented milk and glycerol in a weight ratio of 10:1 and stirred evenly,

[0049] Then add 8% (W / V) gelatin solution of pH 4.0-4.5 (solid content and lactic acid fermented milk weight ratio is (6:3) to emulsify evenly, mass fraction 10% protective agent solution (solid content of solution) Content, according to fermented milk: skimmed milk powder: sodium glutamate: lactose mass ratio 60:36:1:6 mix and stir) emulsification 30min, obtain the emulsion of fermented milk.In above-mentioned emulsion, add the adjuvant of 1...

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Abstract

The invention provides a stabilization coating technology for a composite biological vitamin, particularly a stabilization coating technique for enteric feed biological vitamins. The technique includes preparing a fermentation liquid, performing separation and concentration to obtain fermented milk, and performing biological multi-dimensional granulation, drying, coating and other steps to obtaina composite biological vitamin product. The technique effectively combines lactic acid bacteria, yeast and vitamins into one product, and greatly improves stress resistance of probiotics and vitamins,greatly improves storage stability of probiotics and vitamins, and achieves better tolerance against damage caused by a plurality of harmful factors such as trace metal ions, choline chloride, antibiotics, etc. in feed. A situation that tolerance to high temperature of feed granulation processes is absent is improved, and more importantly, the biological multi-dimensional coated product which cansafely pass through gastric juice and is rapidly disintegrated in the intestinal tract of the animal is prepared.

Description

[0001] Technical field: The present invention relates to the field of feed industry, in particular to the stable coating technology of feed additives Background technique: [0002] Vitamins are necessary for the body to maintain normal metabolism and physiological functions. They are neither energy-supplying substances nor structural components of various tissues and organs in the animal body. They are mainly involved in the body's metabolism in the form of coenzymes (or prosthetic groups). It is a chemical reaction used to control and regulate the metabolism of substances. It is an active substance necessary for life and an essential ingredient in livestock and poultry feed. Lactobacillus is an important probiotic for feed additives. As a probiotic, lactic acid bacteria can regulate the normal flora of the body's gastrointestinal tract, maintain the microecological balance, improve food digestibility and biological value, reduce serum cholesterol, control endotoxin, and inhibi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23K10/12A23K10/18A23K10/20A23K20/163A23K20/174A23K40/30
CPCA23K10/12A23K10/18A23K10/20A23K20/163A23K20/174A23K40/30
Inventor 赵小丽张杰峰
Owner 北京农博微生物科技有限公司
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