Method for preparing alpha-phenylethanol catalyst through hydrogenation of acetophenone and application

Abstract

The invention relates to a method for preparing an alpha-phenylethanol catalyst through hydrogenation of acetophenone and application. The catalyst contains copper oxide, zinc oxide, silicon dioxide and bismuth oxide. The method of the catalyst is realized by virtue of a sub-step precipitation method and comprises the following steps: precipitating zinc salt and a precipitator at a certain temperature, and aging, so as to obtain slurry (1); adding a mixed solution of copper salt and bismuth salt as well as the precipitator into the slurry (1), carrying out coprecipitation, and aging, so as toobtain slurry (2); adding carrier silicon into the slurry (2), and uniformly stirring and mixing, so as to obtain slurry (3); filtering, washing, drying and roasting the slurry (3), so as to obtain catalyst powder; adding a certain amount of pore forming agents into the catalyst powder, and carrying out piece formation; and carrying out secondary roasting on the formed catalyst, so as to obtain the final catalyst. The catalyst prepared by virtue of the method is large in pore volume and aperture, good in mass transfer property and heat transfer property and high in activity and selectivity.

Description

technical field [0001] The invention belongs to the technical field of catalytic hydrogenation, and in particular relates to a preparation method of a catalyst for preparing α-phenethyl alcohol by liquid-phase hydrogenation of acetophenone. Background technique [0002] α-Phenylethyl alcohol is an important chemical intermediate widely used in medicine, fragrance manufacturing, cosmetics, food and fine chemical industries. The existing α-phenylethanol synthesis methods mainly include microbial fermentation and catalytic hydrogenation of acetophenone. [0003] Microbial fermentation generally uses phenylalanine and fluorophenylalanine as raw materials to produce α-phenylethanol through microbial fermentation. The raw materials used in the microbial method are expensive and the production cost is high. At present, the industrial production of α-phenylethanol usually adopts the hydrogenation method of acetophenone. This method has the advantages of low production cost, few by...

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Problems solved by technology

CN1557545A has prepared Ni-Sn-B / SiO2 catalyst by impregnation method, adopts KBH after low-temperature roasting 4 As a reducing agent for reduction, when it catalyzes the reaction, the highest selectivity of phenylethyl alcohol reaches 97.5%, but its active component Ni and carrier SiO 2 Weak interaction, easy to lose

[0006] US4996374 discloses a kind of Pd-C catalyst, but its catalyst stability is relatively poor, needs to constantly improve reaction temperature when applying mechanically

CN1315226A discloses a reduction-treated copper-based catalyst and a method for preparing α-phenylethanol, but it needs to adopt a liquid-phase reduction method to improve the stability of the catalyst, and the process is complicated and the cost is high

CN1911883A discloses a method for preparing α-phenylethanol with Raney nickel as a catalyst, but there are more aromatic ring hydrogenation products α-cyclohexyl alcohol in its acetophenone hydrogenation product, and α-phenylethanol selectivity lower

[0010] In the prior art, copper-based catalysts used in liquid-phase hydrogenation reactions are not only affected by various internal or external forces in the process of storage / filling / reduction / reaction, but also due to liquid immersion, swelling, etc. The strength is greatly reduced, causing the catalyst to be easily broken and pulverized in the liquid phase hydrogenation system, threatening the stable operation of industrial equipment and affecting the life of the catalyst

[0011] At present, the hydrogenation of acetophenone prepared by the precipitation method to prepare α-phenylethyl alcohol copper catalysts usually has problems such as low dispersion of active component copper, strong catalyst acidity, weak interaction between the carrier and the active component, etc., resulting in acetophenone Low conversion rate, large amount of by-products such as ethylbenzene, poor selectivity of phenylethanol, poor catalyst strength

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