Composite plant polyphenol chelate and use method thereof
A technology of plant polyphenols and chelates, applied in the field of animal husbandry, can solve problems such as intestinal epithelial integrity and mucosal barrier damage, intestinal mucosal atrophy, intestinal dysfunction, etc., to enhance intestinal antioxidant capacity, Effect of reducing incidence and suppressing intestinal bacteria and viruses
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[0019] The preparation method of copper baicalin is as follows: obtaining baicalein-7-O-β-D-glucuronide from scutellaria baicalensis; The ratio of 2:1 was reacted in methanol solution at 50 °C for 3 hours to obtain the sediment, and the filter residue was dried at low temperature to obtain copper baicalin;
[0020] The preparation method of 4'-butyryl puerarin is as follows: prepare 8-β-D-glucopyranose-4',7-dihydroxyisoflavone from wild pueraria, and weigh 8- β-D-glucopyranose-4',7-dihydroxyisoflavone and butyric acid chloride were dissolved in equal volumes of saturated sodium hydroxide solution and acetone solution, respectively, and the two solutions were mixed evenly and reacted at 20°C 2.5h, after separation and filtration, 4'-butyric acid puerarin was obtained;
[0021] The preparation method of zinc tannic acid is as follows: obtaining tannic acid from gallnut, reacting tannic acid and zinc chloride in 45° C. ethanol solution according to a mass ratio of 1:1.5 for 2 ho...
Embodiment 1
[0023] According to the mass ratio of copper baicalin, 4'-butyryl puerarin and zinc tannin to be 1:4:5, the compound is mixed evenly to obtain a compound plant polyphenol chelate.
[0024] The compound plant polyphenol chelate in this example is suitable for piglets by drinking water, and the application effect is obvious.
[0025] The piglets were fed with the compound plant polyphenol chelate in this case as drinking water. Twenty-four 7-day-old 2.1±0.5kg Dulong piglets were selected and divided into 3 groups. The blank control group did not add any drugs and health care agents in the drinking water. The experimental group I was given a mixture of doxycycline and amoxicillin by drinking water. 0.5g / L, test group II received the compound plant polyphenol chelate 0.5g / L through drinking water, and the body weight, diarrhea incidence and diarrhea index were counted after the 21-day-old piglet test. The results are shown in Table 1.
[0026] Table 1 Effects of adding this comp...
Embodiment 2
[0031] According to the mass ratio of copper baicalin, 4'-butyryl puerarin and zinc tannin of 1:5:4, the compound is mixed evenly to obtain a compound plant polyphenol chelate.
[0032] The compound plant polyphenol chelate in this example is suitable for laying hens in the way of drinking water, and the application effect is obvious.
[0033] The compound plant polyphenol chelate of this example was fed to the laying hens with enteritis in the way of drinking water. A total of 300 Hailan brown laying hens of the same age who were infected with Mycoplasma and Bacillus caused diarrhea were selected and divided into 3 groups. Test group II received the compound plant polyphenol chelate 0.2g / L treatment for 5 days by drinking water, and the production performance, incidence of diarrhea and intestinal score were counted after the test. The results are shown in Table 2.
[0034] Table 2 The effect of adding this compound plant polyphenol chelate in drinking water on laying hens ...
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