69 results about "Glutarimide" patented technology

Disclosed is the use of certain polyglutarimides as plastic substrates for use in electronic display applications. These substrates have relatively high Tgs for plastics, and good optical clarity and flatness, with low shrinkage and low birefringence. Also disclosed are electronic display cells made using such polyglutarimide substrates.

Provided is a resin composition containing a thermoplastic acrylic resin and an ultraviolet absorber (UVA). While this resin composition has excellent heat resistance because of its high glass transition temperature, foaming and bleed-out can be suppressed and the problems arising from the evaporation of the UVA can be reduced even during the molding of the resin composition at a high temperature. The resin composition is a thermoplastic resin composition containing a thermoplastic acrylic resin and an ultraviolet absorber having a molecular weight of 700 or more, and having a glass transition temperature of 110° C. or higher. It is preferable that the ultraviolet absorber has a hydroxyphenyltriazine skeleton. It is preferable that the acrylic resin has a ring structure in its main chain. The ring structure is, for example, at least one selected from a lactone ring structure, a glutaric anhydride structure, a glutarimide structure, an N-substituted maleimide structure, and a maleic anhydride structure.

The present invention is directed to a multilayer material having in order a layer of fluorinated polymer, a layer of binder for fluorinated polymer having a polymer A with moieties (1)-(4), and a layer of polymer which is incompatible with the fluorinated polymer. The multilayer material is useful for making a pipe which has a superior barrier properties to petroleum products and the additives thereof. The present invention also relates to a pipe having a multilayer structure having two layers of polyamide and a layer of binder comprising a polymer A with glutarimide moieties (1)-(4) in between. The pipe has superior barrier properties to petroleum products and the additives.

Disclosed herein is an acrylic resin film having excellent heat resistance and mechanical strength, less fish-eyes, and high transparency. The acrylic resin film is obtained by molding a resin composition containing a glutarimide acrylic resin (G) and a (meth)acrylic resin (F) obtained by polymerization of a vinyl group-containing compound in the presence of alkyl acrylate-based cross-linked elastic particles having an average particle size of less than 80 nm.

A vehicle part cover including a methacrylic-based resin (I) having a weight average molecular weight measured by gel permeation chromatography (GPC) of 65,000 to 300,000,

• • the methacrylic-based resin (I) comprising:
  • 50 to 97% by mass of a methacrylate monomer unit (A);
  • 3 to 30% by mass of a structural unit (B) having a ring structure in its main chain, and being at least one selected from the group consisting of a maleimide-based structural unit, a glutaric anhydride structural unit, a glutarimide-based structural unit, and a lactone ring structural unit; and
  • 0 to 20% by mass of another vinyl monomer unit (C) that is copolymerizable with a methacrylate monomer.

The invention concerns moulded discs for audio and/or optical information recording media (such as CDS and DVDs) obtained from a thermoplastic polymer material comprising, by weight, (a) 60 to 95%, preferably 70 to 85%, of a thermoplastic resin selected from (1) a methyl methacrylate homopolymer, (2) a copolymer containing in majority units derived from methyl methacrylate monomer, (3) a mixture of the homopolymer (1) and/or of the copolymer (2) with a substituted or unsubstituted styrene copolymer and of at least one monomer selected from (meth)acrylonitrile, maleic anhydride and maleimides or (4) a glutarimide polymer, optionally mixed with a substituted or unsubstituted styrene/(meth)acrylonitrile copolymer and (b) 5 to 40%, preferably 15 to 30%, of at least one impact modifier compound in the form of particles having an average size of between 10 and 200 nm, preferably between 40 and 150 nm.

The invention discloses a novel preparation method of lenalidomide. Glutarimide and 4-nitro-isoindolin-1-one are used as raw materials of the lenalidomide. The lenalidomide is prepared by (1) performing bromination in the alpha position of the carbonyl of the glutarimide to obtain 3; (2) condensing 4-nitro-isoindolin-1-one and the 3 to obtain 4; and (3) subjecting the 4 to reduction to obtain 5, namely the lenalidomide. The preparation method has easily available raw materials, short steps, simple operation, high reaction yield and low production cost, and is environmental friendly. The preparation method has large implement value and social and economic benefit.

The present invention relates to novel biologically active glutarimide derivatives of general formula I or pharmaceutically acceptable salts thereof, their use as an agent for the treatment of upper respiratory tract diseases, pharmaceutical compositions comprising the glutarimide derivatives of general formula I, methods for preparing the glutarimide derivatives of general formula I by heating a dicarboxylic acid monoamide of general formula II with a dehydrating agent.

The invention belongs to the field of radiochemical synthesis, and more specifically relates to radioisotope carbon-14 labelled pesticide chlopyrifos, and a synthesis method thereof. The synthesis method comprises following steps: a metal organic reagent is reacted with [14C] carbon dioxide so as to obtain 5-benzyloxy[carbonyl-14C] pentanoic acid; amidation, debenzylation, and cyclization reactionare adopted so as to realize conversion into [carbonyl-2, 6-14C2] glutarimide; aromatization, chlorination, and hydrolysis are adopted, and an obtained hydrolysate and diethyl thiophosphoryl chlorideare subjected to nucleophilic substitution so as to obtain the carbon-14 labelled pesticide chlopyrifos. The synthetic method is capable of avoiding defects in the prior art; the reaction raw materials are easily available; the reaction conditions are mild; production cost is low; the obtained carbon-14 labelled pesticide chlopyrifos can be taken as a radioactive tracer, can be used in tracing ofpollution evolution rules such as migration conversion, metabolism degradation, and absorption enrichment of chlopyrifos in the environment and in vivo, and can be used for providing technical support for comprehensive evaluation of the biological safety of chlopyrifos; and in addition, the synthesis method is capable of providing reference for preparation of building blocks containing C-14.

The invention relates to 3-isobutyl glutarimide which is the intermediate of pregabalin treating intermediate and preventing epilepsy, and the method for preparing the same. The method comprises preparation of 3-isobutyl glutarimide by using 3-isobutyl glutaric acid and agent containing nitrogen through cyclocondensation reaction, and preparation of S-(+) - 3- isobutyl gamma- aminobutyric acid through Hoffmann rearrangement and S-amygdalic acid resolution. The method is characterized by simple process, easy separation of intermediate product and end product from reacting dissolvent or recrystallization dissolvent, low cost and suitable for industrial production.

The invention discloses the application of biosensing test paper based on N, N'-bis (trimethoxy silicyl propyl)-glutarimide. The biosensing test paper taking N, N'-bis (trimethoxy silicyl propyl)-glutarimide as a color probe is applied to the detection of hydrogen peroxide, glucose or prostate-specific antigen, has special metachromatism to hydrogen peroxide, and has the advantages of high stability and sensitivity, good selectivity; the detection method is fast, simple and economic, and is wide in application range..

This invention provides amine-linked C3-glutarimide Degronimers and Degrons for therapeutic applications as described further herein, and methods of use and compositions thereof as well as methods fortheir preparation.

The present invention relates to novel biologically active glutarimide derivatives of general formula (I) or a pharmaceutically acceptable salt thereof, their use as a therapeutic agent for the treatment of eosinophilic diseases, preferably of allergic nature, in particular bronchial asthma, allergic rhinitis, polypous rhinosinusopathies, eosinophilic colitis, eosinophilic syndrome, allergic conjunctivitis, atopic dermatitis, Churg-Strauss syndrome, anaphylactic shock, Quincke's edema, eosinophilic vasculitis, eosinophylic esophagitis, eosinophilic gastroenteritis, or fibroses. The invention also relates to pharmaceutical compositions comprising glutarimide derivatives of general formula (I):

A polarizing plate includes: a polyvinyl alcohol-based polarizer; and transparent protective films provided on both surfaces of the polyvinyl alcohol-based polarizer with an adhesive layer interposed between each of the transparent protective films and the polyvinyl alcohol-based polarizer. A first transparent protective film contains a (meth)acrylic resin and an ultraviolet absorber, the (meth)acrylic resin having an unsaturated carboxylic acid alkyl ester unit and a glutarimide unit represented by the general formula (1), having an imidization ratio of 2.5 to 5.0% and an acid value of 0.10 to 0.50 mmol/g, and having an acrylic ester unit of less than 1% by weight. A second transparent protective film contains a cycloolefin-based resin.

R¹ and R² each independently represent hydrogen or an alkyl group; and R³ represents an alkyl group, a cycloalkyl group, or an aryl group.

This invention provides Degronimers that have carbon-linked E3 Ubiquitin Ligase targeting moieties (Degrons), which can be linked to a targeting ligand for a protein that has been selected for in vivodegradation, and methods of use and compositions thereof as well as methods for their preparation.

The invention discloses a heat-resistant chlorinated polyvinyl chloride material for power cables. The raw material comprises the following components: chlorinated polyvinyl chloride, polyvinyl chloride, marble, calcium carbonate, calcined kaolin, calcium stearate, stearin Zinc acid, dibutyltin dilaurate, butyl stearate, oxidized polyethylene wax, aluminum hydroxide, magnesium hydroxide, tricresyl phosphate, bis(2‑ethylhexyl)phenyl phosphate, tris(2‑ethylhexyl) phosphate Ethylhexyl) ester, polystyrene, polyglutarimide, stearyl alcohol, silane coupling agent, antioxidant. The heat-resistant chlorinated polyvinyl chloride material for power cables proposed by the invention has high strength, good heat resistance and excellent impact resistance, and the cable material made of the material has good comprehensive performance and long service life.

Disclosed is a resin composition wherein birefringence is controlled. Specifically disclosed is a resin composition essentially containing a resin (A) containing a glutarimide unit and an acrylate unit, and another resin (B) containing a glutarimide unit, an acrylate unit and an aromatic vinyl unit. This resin composition can be easily produced at low cost, and is excellent in transparency and heat resistance. In particular, orientational birefringence can be easily controlled in this resin composition. This resin composition can be used for molded bodies for optical applications which require transparency and heat resistance.

It is an object of the present invention to provide a resin composition whose birefringence has been controlled. The object can be attained by a resin composition composed essentially of a resin (A) containing glutarimide units and acrylic ester units and a resin (B) containing glutarimide units, acrylic ester units, and aromatic vinyl units. The resin composition of the present invention is easy to manufacture, inexpensive, excellent in terms of transparency and heat resistance, and easily controllable in terms of orientation birefringence. Further, the resin composition of the present invention can be developed to be applied to an optical molding product of which transparency and heat resistance are required.

The invention discloses polypeptide, a DNA molecule, a recombination carrier, a transformant, an application of the polypeptide, an application of DNA molecule and an application of the transformant,and belongs to the field of a biological technology. In accordance with the problems that in the prior art, in the process of preparing the intermediate ( the intermediate is(R) 3-carbamoymethyl-5-methylhexanoic acid ) of Pregabalin, a large amount of chloroform is needed in a conventional chemical splitting method, so that the environmental pollution is serious, the invention provides the polypeptide. The polypeptide is used, so that 3-Isobutyl glutarimide can be hydrolyzed to obtain the (R) 3-carbamoymethyl-5-methylhexanoic acid which is high in 3-Isobutyl glutarimide and high in yield.