The invention discloses a farming box for industrial insect farming and a cleaning method thereof. The farming box comprises a frame body and a sealing mechanism, wherein the sealing mechanism comprises four baffles, the four baffles are connected end to end to form a rectangular structure, top edge bars are arranged on the top faces of the baffles, an annular groove is formed in the top face of the frame body, the top edge bars are matched with the annular groove, and a position mechanism is arranged between every two adjacent baffles. The cleaning method comprises the steps of manufacturingof a box body, installation of a clamping mechanism, installation of a hanging mechanism, installation of a spraying mechanism and cleaning of the farming box. Due to the design of the sealing mechanism, in the transfer process of the farming box, the influence of strong light on insects can be reduced, the influence of strong external wind power on the interior of the farming box can be reduced,and the insect surviving rate is improved. The cleaning method is simple, the cleaning requirements of the farming boxes of different sizes can be met, waste of water resources is reduced through circulating cleaning, and the cleaning effect is improved.