64 results about "Intraventricular Cardiac" patented technology

The present application relates to the field of medical devices, and specifically to a repair device for preventing valve regurgitation, comprising a mounting bracket, a single anti-reflux prosthesis for replacing the function of a single native valve leaflet, and a fixing member, wherein one end of the single anti-reflux prosthesis is fixed on the mounting bracket, and an atrial segment is provided at the distal end of the mounting bracket, and the atrial segment is configured to adapt to the morphology of the native valve ring tissue, and the atrial segment includes a leak-proof portion, and the proximal end portion of the mounting bracket is anchored in the ventricle by the fixing member, wherein, after the mounting bracket is installed in place, the leak-proof portion abuts against or fits the native valve ring tissue, and when the native valve opens and closes so that the morphology of the native valve ring changes, the leak-proof portion follows the morphological change of the native valve ring and produces adaptive deformation, so that the leak-proof portion always abuts against or fits the native valve ring tissue.

The utility model discloses a double-gas-path gas source system and a double-gas-path heart auxiliary system. The double-air-path heart assisting system comprises a pressure generating mechanism which alternately generates positive pressure and negative pressure when working; the first auxiliary device comprises first driven equipment and a first piping pipeline, a pipe body at the farthest end of the first piping pipeline is provided with an inflow channel and an outflow channel, and the first driven equipment is located in the pipe body of the first piping pipeline and corresponds to the outflow channel in position; the second auxiliary device comprises second driven equipment and a second piping pipeline communicated with the second driven equipment; the pressure generating mechanism enables the second driven device to repeatedly expand and contract through the second piping. The detection device is used for acquiring the pressure in the cardiac chamber and the pressure in the aorta; and the control mechanism is used for controlling the pressure generation mechanism to respectively drive the first driven equipment and the second driven equipment according to the corresponding time sequence in a cycle control period according to the pressure signal sent by the detection device.

Apparatus and methods are described including a valve frame configured to support a prosthetic valve within a native atrio-ventricular valve. The valve frame includes an atrial part comprising a disc-shaped portion configured to be deployed on an atrial side of the valve annulus, and a frustoconical portion, and a cylindrical part to which the prosthetic valve leaflets are coupled. The cylindrical part configured to be deployed such that a ventricular end of the cylindrical part is disposed within the ventricle. A plurality of protruding struts are configured to protrude from outside the cylindrical part, the frustoconical portion of the atrial part being coupled to the cylindrical part via the protruding struts. Other applications are also described.

The invention discloses a magnetic-coupling-driven auxiliary pressurization system for a paddle in a ventricle, relates to the technical field of medical instruments, and can solve a series of problems caused by integrated design of a motor and a paddle of an existing auxiliary pressurization device for the ventricle. The embodiment of the invention discloses a magnetic coupling driven heart chamber inner paddle auxiliary pressurization system which comprises a paddle part used for being sewn and fixed to the inner wall of a heart chamber and a driving part used for being sewn and fixed to the outer wall of the heart, and the paddle part comprises an inner sleeve, a paddle structure and a driven magnetic disc coaxially and fixedly connected with the paddle structure. The paddle structure is rotationally connected into the inner sleeve; the driving part comprises an outer sleeve, a driving motor and a driving magnetic disc coaxially and fixedly connected with an output shaft of the driving motor, and the driving motor is fixed in the outer sleeve; when the paddle part and the driving part are in a sewed and fixed state, the driven magnetic disk and the driving magnetic disk are coaxial and are magnetically coupled, and the paddle structure is driven by the driving motor to rotate through the driving magnetic disk and the driven magnetic disk which are magnetically coupled.

Disclosed in the present application is a catheter pump system. A measured intraventricular pressure and a measured intravascular pressure are measured by means of dual sensors, respectively, and an estimated intraventricular pressure is calculated by using the measured intravascular pressure, a motor current, and a motor rotation speed. When it is determined that a suction event occurs in a pump assembly by using at least one of the estimated intraventricular pressure, the measured intravascular pressure, and the motor current, the root cause of the suction event is further determined by using the positive or negative characteristics of the measured intraventricular pressure.

The invention provides a stepped ventricle auxiliary circulating pump device, relates to the technical field of heart blood pumps, and provides a structure that a heart blood pump is arranged in a heart chamber and below an aortic valve or a pulmonary valve, and a stepped motor and an axial flow channel are designed on the basis, so that a blood flow channel is formed between the motor and the axial flow channel; the blocking influence of the size of the motor above the aortic valve or the pulmonary valve on the blood circulation process can be effectively avoided, and the amount of blood pumped out of the aortic valve or the pulmonary valve is effectively increased.

The invention provides a close-range valve-pump integrated ventricular auxiliary circulating pump device, and relates to the technical field of heart blood pumps, the close-range valve-pump integrated ventricular auxiliary circulating pump device comprises a ventricular auxiliary circulating pump device, the ventricular auxiliary circulating pump device is connected in series with a heart artery tube, and the ventricular auxiliary circulating pump device is arranged in a heart chamber and below an aortic valve or a pulmonary artery valve; the ventricular auxiliary circulating pump device comprises an axial flow channel and a power part located in the axial flow channel. The upper end of the axial flow channel is provided with a radially outward turnup part, the turnup part faces the lower surface of the aortic valve or the pulmonary valve and is sewn at the aortic root or the pulmonary artery root, the turnup part serves as a mounting plane, and the power part is provided with an impeller rotating in the axial direction of the axial flow channel. The plane of the outlet of the impeller and the plane where the flanging part is located are the same plane, and direct adjacent maximum pressure of the ventricular auxiliary circulating pump device is provided for the aortic valve or the pulmonary valve.

The present invention provides a close-range valve pump integrated ventricular assist circulation pump device, which relates to the field of cardiac blood pump technology and includes: a ventricular assist circulation pump device, which is connected in series with the cardiac artery tube, and the ventricular assist circulation pump device is arranged in the ventricle and below the aortic valve or the pulmonary valve; the ventricular assist circulation pump device includes an axial flow channel and a power unit located in the axial flow channel; the upper end of the axial flow channel is provided with a radially outward flange portion, the flange portion faces the lower surface of the aortic valve or the pulmonary valve and is sutured to the aortic root or the pulmonary artery root, the flange portion serves as an installation plane, the power unit has an impeller rotating in the axial direction of the axial flow channel, and the impeller outlet plane is in the same plane as the plane where the flange portion is located, providing the ventricular assist circulation pump device with a maximum pressure directly adjacent to the aortic valve or the pulmonary valve.

The application discloses an ultrasonic probe capable of directly reaching into a heart chamber in a heart operation and relates to the technical field of medical devices. The ultrasonic probe comprises a fixing frame arranged around the heart chamber, the fixing frame being connected with the skin of a patient; a telescopic rod being perpendicular to the fixing frame and being connected with the fixing frame through a spherical hinge, the telescopic rod being capable of extending into the heart chamber of the patient; an ultrasonic probe being arranged on the side wall of the end of the telescopic rod away from the fixing frame, the ultrasonic probe being arranged in the circumference of the telescopic rod, and the ultrasonic probe being provided with a plurality of ultrasonic probes; and a camera being arranged at the end of the telescopic rod away from the fixing frame. The length of the ultrasonic probe extending into the heart chamber of the patient can be changed through the arrangement of the telescopic rod, and the different heart chambers of different patients can be detected. The ultrasonic probe can be fixed on the skin of the patient through the arrangement of the fixing frame. The telescopic rod can be rotated according to the different positions of the diseased parts of different patients through the spherical hinge connection between the fixing frame and the telescopic rod, so that the ultrasonic probe can be in a better detection position.

The present invention discloses a biopsy forceps guiding catheter that can be used for zero-ray myocardial biopsy, comprising a catheter body, wherein a central cavity penetrating through both axial ends of the catheter body is provided inside the catheter body, at least one electrode element is provided at the first axial end of the catheter body, an airbag component is provided at the first axial end of the catheter body near the rear side of the electrode element, the electrode element is connected to an electrical connection assembly extending to the second axial end of the catheter body, the electrical connection assembly is connected to an electrocardiogram monitor, and the airbag component is connected to a ventilation assembly extending to the second axial end of the catheter body. The electrocardiogram and injury current in the cardiac cavity are recorded by the electrocardiogram monitor leads to select a site with a significant injury current for sampling, thereby reducing the influence of scars and fat tissue on the quality of the sampled sample, and the airbag component can drift and move with the blood, thereby solving the problem that the current biopsy forceps need to rely on X-ray guidance to be delivered into the ventricle and it is difficult to accurately obtain a specific layer of myocardium under the endocardium during sampling.

Methods, apparatus, and systems are provided to control contraction of the heart. At least one sensing element receives signals indicating electrical activity of sinus rhythm of the heart. Based on the received signals, the progress of contraction of the heart is determined. Based on the progress of contraction, the chamber of the heart may then be stimulated at a plurality of locations. In another embodiment, a plurality of electrodes are implanted in the left ventricle to stimulate at multiple locations in the left ventricle for the purpose of improving hemodynamic performance and increasing cardiac output in a patient who is suffering from congestive heart failure.

The present document relates to a device for fixing a cardiac pump in an opening of a ventricular wall of a beating heart. The device includes: a hollow main body of overall cylindrical shape having an outer surface, this hollow main body includes a proximal end and a distal end between which said the outer surface extends, at least one portion of the outer surface of the main body intended to be placed inside ventricular cavity, except for its distal end, has a surface relief provided with protuberances and hollows, the distal end of the hollow main body forms a smooth crown having an arithmetic average roughness of less than or equal to 1 μm in order to stop the colonization of the fixing device by endothelial cells.

An apparatus and method are described that includes an axial shaft (92) configured to be inserted into and rotate within a ventricle of a subject's heart. An impeller (50) is coupled to the axial shaft (92), and a frame (34) surrounds the impeller. A pump outlet tube (24) surrounds the frame such that, as the axial shaft (92) rotates, the impeller (50) pumps blood proximally from the ventricle through the pump outlet tube (24). An inlet guard (400) shaped to define one or more holes (402) is disposed around the axial shaft (92) and within the frame (34) distal to the impeller (50) so that blood flows through the holes (402) to the impeller (50). Other applications are also described.

The invention belongs to the technical field of new application of medicines, and provides application of Zhongwinning in preparation of a medicine for treating ischemic heart disease. In a myocardial ischemia rat model test, Zhongwinning shows that the Zhongwinning can obviously improve the left ventricular ejection fraction and the left ventricular short-axis shortening rate of a myocardial ischemia rat; in addition, the rising and falling rates of the ventricular pressure of the myocardial ischemia rats can be remarkably improved, and it is indicated that Zhongutanin can effectively recover the left ventricular systolic function and can effectively repair myocardial injury caused by myocardial ischemia reperfusion. Therefore, according to the experimental research result of the application, the Zhongwinning has a certain application prospect in treating the ischemic heart disease.

Aspects of the disclosure include transcatheter delivery devices for delivery and deployment of a cardiac prosthesis, such as a prosthetic heart valve. Various embodiments include a one or two part capsule for maintaining the prosthesis during delivery. Embodiments include a flexible capsule that can deflect, either automatically or in response to contact with the anatomy, to reduce a delivery depth within a ventricle necessary to fully unsheathe the prosthesis, which increases the patient population and valve locations suitable for prosthesis delivery with the delivery device.

This invention belongs to the field of novel pharmaceutical applications, providing the application of Zhongwu Ning in the preparation of drugs for treating ischemic heart disease. In rat models of myocardial ischemia, Zhongwu Ning significantly increased the left ventricular ejection fraction and left ventricular fractional shortening rate; it also significantly improved the rate of increase and decrease of intracardiac pressure in rats with myocardial ischemia, indicating that Zhongwu Ning can effectively restore left ventricular systolic function and effectively repair myocardial damage caused by myocardial ischemia-reperfusion. Therefore, based on the experimental research results of this application, Zhongwu Ning has certain application prospects in the treatment of ischemic heart disease.

Apparatus and methods are described including a frame (20) includes an atrial part (26) that includes a disc-shaped portion (28) configured to be deployed on an atrial side of the valve annulus, and a cylindrical part (22) configured to be deployed such that a ventricular end of the cylindrical part (22) is disposed within the ventricle. The cylindrical part (22) is coupled to the atrial part, via one or more sutures (132), at a plurality of junctions (67) that are disposed around a circumference of the frame (20), and each of the junctions (67) is individually padded with a covering material (32). Other applications are also described.

The present application discloses a guidewire device with improved support effects, comprising a guide tube and a guidewire slidably disposed within the guide tube. The guidewire has opposing distal and proximal ends, wherein the distal end of the guidewire has a stowed state within the guide tube and an expanded state in which the guidewire is exposed. In the expanded state, the distal end of the guidewire forms a three-dimensional mesh cage structure. Compared to existing technologies, this solution enables the guidewire device to form a three-dimensional mesh cage structure within the ventricle. The mesh cage structure and the inner wall of the left ventricle form a surface support as a whole. The stress acting on the distal end of the guidewire is dispersed by the mesh cage structure, thereby preventing damage to the left ventricle.

A system includes a catheter, an electrocardiogram (ECG) system, and a processor. The catheter is configured to apply pacing to a given tissue location inside a ventricle of a heart of a patient. The ECG system is configured to acquire a set of ECG signals generated in response to the pacing, wherein electrodes of the ECG system attached to the patient define respective directions in space with respect to an origin located in the heart. The processor is configured to (i) compute a set of respective signal differences between the acquired set of ECG signals and a reference set of ECG signals, (ii) compute a set of corresponding deviation vectors along the respective directions in the space, the deviation vectors having magnitudes corresponding to the respective signal differences, (iii) using the deviation vectors, compute a direction vector from the given location to a new ventricle location at which to apply the pacing, and (iv) indicate the computed direction vector to a user.

The application provides a blood pump, which comprises a pump shell, a pipeline assembly and an impeller, the pump shell is provided with a receiving cavity; the pipeline assembly comprises a liquid outlet pipe communicated with the receiving cavity, the liquid outlet pipe is provided with a liquid outlet, the pipeline assembly is further provided with a liquid inlet, the liquid inlet is communicated with the receiving cavity, the pipeline assembly can be arranged on the ventricular wall so that the liquid inlet is located in the ventricle, the liquid outlet pipe has a certain length, so that when the pipeline assembly is arranged on the ventricular wall, the liquid outlet pipe can extend to the aortic valve through the ventricle, and the liquid outlet is located in the aorta; the impeller is rotatably arranged in the receiving cavity, so that the liquid in the receiving cavity from the liquid inlet can flow out from the liquid outlet through the liquid outlet pipe. The blood pump provided by the application can pump the blood in the ventricle to the aorta without setting an artificial blood vessel, avoids the aortic diseases such as dissection and hematoma caused by the hole on the aorta, and reduces the operation difficulty. The application further provides a ventricular assist system.

This invention relates to a distal extension of a blood pump, an inlet window assembly, and a blood pump. The distal extension includes an extension tube and a protective end. The protective end is connected to one end of the extension tube. The distal extension has a guidewire channel that extends through the extension tube and the protective end, forming a first opening on the protective end that communicates with the guidewire channel. The protective end also has multiple connecting holes that communicate with the guidewire channel. Each connecting hole has a second opening located on the outer surface of the protective end. The second openings of the multiple connecting holes are spaced apart around the guidewire channel. Therefore, when the distal extension extends into the ventricle of the heart, and the first opening and the second opening on one side of the outer surface of the protective end are blocked by the inner wall of the heart, at least one second opening on the other side of the outer surface of the protective end is exposed in the ventricle, allowing blood to flow out through the guidewire channel and the second opening, reducing the formation of thrombi caused by blood remaining in the guidewire channel.

A method for treating a patient includes delivering a distal portion of an elongate medical device into a ventricle of a beating closed heart of a subject via a primary skin opening and a secondary puncture, utilizing the distal portion of the elongate medical device to engage a plurality of chordae tendineae extending from a first papillary muscle within the ventricle, at least a first one of the plurality of chordae tendineae attached to a first leaflet of an atrioventricular valve located between the ventricle and an adjacent atrium, and at least a second one of the plurality of chordae tendineae attached to a second leaflet of the atrioventricular valve, approximating the engaged plurality of chordae tendineae to increase an amount of closure possible between the first leaflet and the second leaflet, and locking the plurality of chordae tendineae in their approximated condition.

The present invention relates to the field of stable biopolymer compositions, in particular to stable biopolymer compositions comprising a liquid mixture, in particular an aqueous solution, of at least one biopolymer component and at least one stabilizing surfactant. More specifically, the present invention relates to a stable biopolymer composition comprising an ethylene oxide / butylene oxide block copolymer capable of imparting superior properties to said biopolymer composition, in particular in terms of aggregation tendency, hemolytic activity and solubility, compared to currently known formulations. The invention also relates to said block copolymer, to a method for preparing said stable composition and to the use of said block copolymer for stabilizing an aqueous composition of said biopolymer. The invention also relates to said stable composition for use in medicine, in particular for diagnostic and / or therapeutic applications. The invention also relates to a substantially dry biopolymer composition comprising the biopolymer and the block copolymer, and to a process for preparing the substantially dry composition. The invention also relates to said substantially dry biopolymer composition for use in medicine, in particular for diagnostic and / or therapeutic applications. The compositions can be formulated as pharmaceutical compositions that can be delivered by suitable routes of administration, such as by oral administration, rectal administration, transmucosal administration, topical administration, ocular administration, aural administration, or enteral administration; parenteral delivery, including intramuscular injection, subcutaneous injection, intramedullary injection, and intrathecal injection, direct intraventricular injection, intravenous injection, intraperitoneal injection, intranasal injection, or intraocular injection, depending on conditions.

A method for treating a patient includes delivering a distal portion of an elongate medical device into a ventricle of a beating closed heart of a subject via a primary skin opening and a secondary puncture, utilizing the distal portion of the elongate medical device to engage a plurality of chordae tendineae extending from a first papillary muscle within the ventricle, at least a first one of the plurality of chordae tendineae attached to a first leaflet of an atrioventricular valve located between the ventricle and an adjacent atrium, and at least a second one of the plurality of chordae tendineae attached to a second leaflet of the atrioventricular valve, approximating the engaged plurality of chordae tendineae to increase an amount of closure possible between the first leaflet and the second leaflet, and locking the plurality of chordae tendineae in their approximated condition.

A method is disclosed for continuous or intermittent wireless monitoring of cardiac ventricular volume with the ability to combine with pressure measurements for optimal remote monitoring of cardiac patients. A set of wireless position sensors or reflectors is placed within a cardiac ventricle (i.e., the left ventricle), the method including means for sensing pressure within one or more cardiac ventricles, and an external device configured to interrogate the wireless sensors to determine their relative and / or absolute positions with respect to each other and / or an external device, calculate the resulting ventricular volume, and create a pressure-volume loop.

The present application relates to an interventional pump based on a micro pressure sensor and a method for determining its implantation position, which includes: a pressure sensor for real-time acquisition of pressure values ​​in a preset area during the rapid ejection period; a pump body and a drive motor, wherein the drive motor provides driving power to the pump body so that the pump body provides a flow path for blood; and a management system for data processing and fitting the pressure values ​​to obtain a pressure-position function within the left ventricle, and performing a consistency test on the pressure-position function. After the consistency test of the pressure-position function passes, the implantation position of the interventional pump is obtained from the pressure value. This solves the problem that the current traditional cardiac interventional pump cannot accurately obtain the real-time position of the interventional pump within the ventricle when the interventional pump is in operation, which greatly affects the safety and efficiency of artificial heart surgery.

The application discloses a detachable leadless pacemaker system which can pace cardiac conduction bundle. The specific embodiment of the system comprises: a detachable leadless pacemaker, the detachable leadless pacemaker is provided with a first data interface; a passive leadless pacemaker, the passive leadless pacemaker is provided with a second data interface; a signal line, which is connected with the first data interface and the second data interface respectively, so as to realize power supply of the detachable leadless pacemaker for the passive leadless pacemaker and data communication between the two. The detachable leadless pacemaker can be arranged in a ventricle to realize atrioventricular dual chamber pacing with the passive leadless pacemaker arranged in an atrium. An unpackaged circuit can be arranged in the passive leadless pacemaker, which is used as an electrode carrier for sensing atrial electrical signals and implementing electrical stimulation. The detachable leadless pacemaker and the passive leadless pacemaker are connected by a tensile-resistant reinforcing line, which is used for recovery operation when the detachable leadless pacemaker is repositioned.

The blood pump (10) and ventricular assist system include a pump case (11) having a housing cavity (112), a conduit assembly (13), and an impeller (15). The conduit assembly (13) includes a liquid discharge tube (133) communicating with the housing cavity (112) and having a liquid outlet (1332), and further includes a liquid inlet (1312) communicating with the housing cavity (112). The conduit assembly (13) is capable of being drilled into the ventricular wall to position the liquid inlet (1312) within the ventricle, and the liquid discharge tube (133) has a certain length so that, when the conduit assembly (13) is drilled into the ventricle wall, the liquid discharge tube (133) can be extended through the ventricle until it drills through the aortic valve to position the liquid outlet (1332) in the aorta. The impeller (15) is rotatably housed in the housing cavity (112).

The application discloses a double-gas-path air source system, a double-gas-path heart auxiliary system and a use method. The double-gas-path heart auxiliary system comprises a pressure generating mechanism, a first auxiliary device, a second auxiliary device, a detection device and a control mechanism. The pressure generating mechanism alternately generates positive pressure and negative pressure during work. The first auxiliary device comprises a first driven device and a first pipe line, and a tube body at the farthest end of the first pipe line is provided with an inflow and an outflow. The first driven device is located in the tube body of the first pipe line and corresponds to the position of the outflow. The second auxiliary device comprises a second driven device and a second pipe line in communication with the second driven device. The pressure generating mechanism makes the second driven device repeatedly expand and contract through the second pipe line. The detection device is used for acquiring the intraventricular pressure and the intra-aortic pressure. The control mechanism controls the pressure generating mechanism to drive the first driven device and the second driven device according to the corresponding time sequence in a cycle control period according to the pressure signal sent by the detection device.