The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicinal prescription for nourishing kidney and blood. The traditional Chinese medicinal prescription comprises the following components in parts by weight: 5-15 parts of American ginseng, 4-20 parts of radix polygonati officinalis, 5-20 parts of astragalus membranaceus, 5-20 parts of prepared rehmannia, 3-12 parts of cornus pulp, 4-20 parts of glossy privet fruit, 5-15 parts of roasted tortoise shell, 2-8 parts of human placenta, 4-15 parts of herba epimedii, 3-12 parts of Chinese holly leaf, 4-20 parts of Chinese angelica, 4-20 parts of ligusticum wallichii, 3-10 parts of rhizoma atractylodis macrocephalae, 2-8 parts of antler gum, 4-12 parts of cortex phellodendri, 5-12 parts of rhizoma anemarrhenae, 5-15 parts of dodder, 3-10 parts of herba taxilli, 5-12 parts of liquorice, and 5-15 parts of white peony root. The traditional Chinese medicinal prescription prepared by adopting the prescription and the method has the beneficial effects of effectively changing the state of deficiency of kidney-yin and deficiency of kidney-yang and remarkably improving the sub-health state of bodies, is quick in response, and does not have toxic or side effect.