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64results about How to "Improve typing efficiency" patented technology

ABO blood type system typing method based on sequencing data and application thereof

The invention discloses an ABO blood type system typing method based on sequencing data and application thereof. The method according to the invention comprises the steps of analyzing sequencing dataof a to-be-tested sample by means of a reference sequence and a Bayes classification training data set, and particularly, comparing the sequencing data of the to-be-tested sample for obtaining position and variation information relative to the reference sequence; according to the compared reads information, for each exon, performing assembling overlapping and using the reads with consistent overlapping sequence as a haplotype; according to the number of support reads and coverage score, taking out the haplotype according to the score from highest to lowest, and constructing a candidate haplotype; performing arrangement combination on the variations of all candidate haplotypes, performing scoring based on no contradiction of a distance between the haplotype obtained through arrangement combination and the haplotype in a database, the P value of Bayes classification, the number of support reads and the type, and selecting two haplotypes with highest scores as the final ABO blood type ofthe to-be-tested sample. The method of the invention has advantages of improving blood type typing accuracy, analyzing potential new blood types and performing large-batch analyzing.
Owner:SHENZHEN HUADA GENE INST

Die blank printing assisting device

A die blank printing assisting device comprises a transverse guide rod, fixed seats, a sliding seat and a character code sleeve part. The fixed seats are arranged at the two ends of the transverse guide rod in a sliding manner and fixed to a die blank. The transverse guide rod is sleeved with the sliding seat in a sliding manner. The character code sleeve part is arranged at the front end of the sliding seat in the manner that the character code sleeve part can move up and down relative to the die blank. Due to the fact that the transverse guide rod is arranged, the fixed seats and the sliding seat which slide along the transverse guide rod are arranged on the transverse guide rod, and the character code sleeve part is arranged on the sliding seat, the fixed seats can be adjusted in a sliding manner to be fixed to the die blank according to the size of the die blank, and the sliding seat is adjusted in a sliding manner according to the position with the character printing requirement to locate the character code sleeve part to the die blank; the character code sleeve part is dually located through the fixed seats and the sliding seat; character printing efficiency and quality can be effectively improved; manual localization is not needed; use safety is high; use is convenient; and the device can be suitable for flexible adjustment and use of die blanks of different sizes.
Owner:SHENZHEN BAOHONG PRECISION MOLD

Character printing fixture for left support and right support of oil pipe of automobile rear axle

The invention discloses a character printing fixture for a left support and a right support of an oil pipe of an automobile rear axle. The character printing fixture comprises an operation table, a top plate, a bearing block, a cylinder I, a connection plate, a cylinder II, a press plate and a character printing block. The character printing fixture is characterized in that the operation table isarranged on a support; the top plate is arranged on a vertical column; bearing grooves are formed in the bearing block, and an installation plate is arranged on the bearing block; a fixing groove penetrating through the bearing block is formed in each bearing groove; the cylinder I is arranged on the operation table; the connection plate is arranged on a piston rod I; the cylinder II is arranged on the top plate; and the press plate is arranged on a piston rod II. According to the character printing fixture, a reinforcing block is arranged between the character printing block and a fixed rod,the connection strength between the character printing block and the fixed rod is increased through the reinforcing block, and a downward impact force generated along with the fixed rod, of the character printing block, under the action of the cylinder II and the piston rod II, is increased, and then the character printing quality for the left support and the right support of the oil pipe of the automobile rear axle is improved.
Owner:WUHU PENGXIANG AXLE CO LTD

A human venous thrombosis risk gene f5 and pai-1 polymorphism detection kit and its preparation method and application

The invention eblogns to the technical field of biology and specifically relates to a human phlebothrombosis risk gene F5 and PAI-1 polymorphism detection kit as well as a preparation method and application thereof. The kit is prepared from a detection reagent, a positive control product and a negative control product, wherein the detection reagent is used for amplifying gene F5 and PAI-1 polymorphism related to the human phlebothrombosis risk, wherein the detection reagent applied to the F5 gene polymorphism is prepared from a primer sequence, a PNA sequence and PCR reaction liquid; the primer sequence is used for amplifying an rs6025 site of F5 gene; the detection reagent applied to the PAI-1 gene polymorphism is prepared from a primer sequence, a PNA sequence and PCR reaction liquid; the primer sequence is used for amplifying an rs17999762 site of the PAI-1 gene. The kit disclosed by the invention is used for detecting the human aspirin resistance gene polymorphism and has the advantages of high flexibility, high specificity, convenience in operation, reliable results and the like; furthermore, detection can be finished within 1 hour, and result reading is simple and objective.
Owner:WUHAN HEALTHCHART BIOLOGICAL TECH

Genotyping method, device, electronic device and storage medium

Embodiments of the present invention provide a genotyping method, device, electronic device, and storage medium, wherein the above-mentioned genotyping method includes: acquiring a sequence to be typed, a reference sequence in a preset gene bank, and a first difference The result set, the preset gene library includes multiple candidate reference sequences, the first difference result set includes multiple first difference results corresponding to the multiple candidate reference sequences respectively, and the first difference results are used to characterize the corresponding candidate reference sequences and benchmarks Difference between reference sequences; obtain the second difference result between the sequence to be typed and the reference reference sequence; determine the target reference sequence from multiple candidate reference sequences, and the target reference sequence is the corresponding first difference result and the second difference result Candidate reference sequences that satisfy the first preset condition between the differences; determine the typing result of the sequence to be typed according to the target reference sequence. The embodiments of the present invention can effectively reduce the processing amount of data and improve the efficiency of comparison and genotyping.
Owner:CHANGSHA DUXACT BIOTECH CO LTD +1
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