Semi-quantitative detection method for residue of bleaching and coloring agents in traditional Chinese medicinal materials and traditional Chinese medicinal decoction pieces

Abstract

The invention provides a semi-quantitative detection method for residue of bleaching and coloring agents in traditional Chinese medicinal materials and traditional Chinese medicinal decoction pieces. The method comprises the following steps of: reacting the treated sample with solution of sodium hydroxide, and taking 2ml of the upper clarified solution as test solution; and adding the 2ml of test solution into a vial filled with arsenic-free zinc granules, adding 2ml of hydrochloric acid, uniformly mixing, and tightly adhering lead or copper ion test paper to the opening of the vial immediately; and if the solution turns yellowish-brown to silver black within ten minutes, preliminarily determining that the sample contains sulfite bleaching and coloring agents, wherein the lead or copper ion test paper is lead acetate test paper, copper acetate test paper or copper sulfate test paper. The method has the advantages that: the vial is convenient to carry, the method is easy to operate, low in cost and high in accuracy, the residual can be detected quickly, semi-quantitative measurement is adopted and the like; moreover, the method greatly shortens the detection time, and is applicable to supervising of rapid screening of the residue of bleaching and coloring agents in the traditional Chinese medicinal materials and the traditional Chinese medicinal decoction pieces on site and performing semi-quantitative analysis.

Description

technical field [0001] The invention relates to physical and chemical analysis of chemical substances, in particular to a semi-quantitative detection method for residual bleaching and coloring agents in Chinese medicinal materials and Chinese medicinal slices. Background technique [0002] Scientific studies have shown that long-term or high-dose intake of sulfite can cause damage to the gastrointestinal tract and liver, and sulfur dioxide can damage the reproductive system of male mice. Since the 1980s, research on the safety of sulfites has attracted more and more attention from various countries. [0003] The traditional processing methods of sulfur fumigation or soaking Chinese herbal medicines will lead to a large amount of sulfur dioxide, arsenic, mercury and other toxic and harmful substances remaining in the original medicine of Chinese herbal medicines. Therefore, "The Pharmacopoeia of the People's Republic of China" (2000 Edition) stipulates that, except for yam, ...

AI Technical Summary

Problems solved by technology

Because this type of substance has the same strong reducing property as sulfur dioxide, it has good bleaching, anti-oxidation and anti-corrosion effects. Similarly, it also brings great hidden dangers to the safe use of Chinese medicinal materials and Chinese herbal medicines.

At present, the legal method to detect whether there is sulfur dioxide residue in Chinese herbal medicines and herbal pieces is the distillation titration method. This method uses a glass instrument device, which is large in size, has many connecting parts, and uses nitrogen gas. The operation time is too long and must be carried out in the laboratory. and some studies try to learn from the rose paraaniline colorimetric method or ion chromatography detection of sulfur dioxide in food, but either use the toxic reagent tetrachloro amalgam and the processing conditions are relatively high, or the equipment used is expensive and has a large volume , The detection environment has high requirements and the processing conditions are strict, so it is not convenient to carry out on-site supervision and use

At present, there is no research on simple and rapid detection methods using chemical methods, especially no research on the use of filter paper as a carrier for separation, diffusion, and chemical reaction color development to simultaneously semi-quantitatively detect the residual inorganic chemical components of Chinese herbal medicines and Chinese herbal medicines. Therefore, this paper The study of the law has more practical significance for supervising on-site rapid detection, timely detaining unscrupulous merchants for illegal processing, and using bleaching and coloring agents for Chinese medicinal materials and Chinese medicinal pieces.

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