Chinese medicine soft capsule for treating upper respiratory infection and preparation method as well as quality detection method thereof
A technology for upper respiratory tract and soft capsule, which can be used in capsule delivery, pharmaceutical formulations, respiratory diseases, etc., and can solve problems such as unqualified disintegration, increased gelatin cross-linking, and delamination.
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Embodiment 1
[0061] 【Prescription】 Contents:
[0062] Softgel skins:
[0063] 1000 traditional Chinese medicine soft capsules are made altogether with the crude drug and pharmaceutical adjuvant of above-mentioned weight.
[0064] [Preparation method] ① Take the extract of Scutellaria baicalensis and the extract of Gardenia jasminoides, grind them separately, pass through a 90-mesh sieve, slowly add the fine powder to soybean oil in stages, mix well, add lecithin, beeswax, glycine I and cysteine 1. Mix evenly, grind and mix with colloid mill for 35 minutes to obtain liquid medicine, store it in another device, and let it stand for later use; ② Take gelatin, glycerin, sorbitol and water, put them in a colloidal sol tank, fully swell, keep warm at 65°C for 35 minutes, add Glycine II, cysteine II, titanium dioxide, chocolate brown and ethyl p-hydroxybenzoate, stirred for 40 minutes, vacuum degassed for 35 minutes to obtain glue, stored in another container, kept at 50°C for later use; ③...
Embodiment 2
[0085] 【Recipe】 Contents:
[0087] 1000 traditional Chinese medicine soft capsules are made altogether with the crude drug and pharmaceutical adjuvant of above-mentioned weight.
[0088] [Preparation method] (1) Traditional Chinese medicine soft capsule: ① Take the extract of Scutellaria baicalensis and the extract of Gardenia jasminoides, grind them separately, pass through a 60-mesh sieve, and slowly add the fine powder to corn oil in stages, mix well, add carbomer, formazan Base cellulose, citric acid and sodium sulfite, mix well, grind and mix in a colloid mill for 55 minutes, store in another container, and let it stand for later use; ② Take gelatin, xylitol and water, put them in a colloidal sol tank, fully swell, and keep warm for 55 minutes at 75°C , add fumaric acid, sodium metabisulfite, zinc oxide, brown iron oxide and potassium sorbate, stir for 60 minutes, vacuum degas for 55 minutes, store in another container, and keep warm at 60°C fo...
Embodiment 3
[0106] 【Prescription】 Contents:
[0107] Softgel skins:
[0108] 1000 traditional Chinese medicine soft capsules are made altogether with the crude drug and pharmaceutical adjuvant of above-mentioned weight.
[0109] [Preparation method] (1) Traditional Chinese medicine soft capsule: ① Take the extract of Scutellaria baicalensis and the extract of Gardenia jasminoides, grind them separately, pass through an 80-mesh sieve, and slowly add the fine powder to soybean oil in stages, mix well, add lecithin, beeswax, Glycine I and cysteine I were mixed evenly, and the colloid mill was ground and mixed for 45 minutes. Minutes, add glycine II, cysteine II, titanium dioxide, chocolate brown and ethyl p-hydroxybenzoate, stir for 50 minutes, vacuum degass for 45 minutes, store in another container, keep warm at 55°C for later use; ③In the soft capsule unit, Use a roller to make the glue solution into a rubber plate, inject the liquid medicine into the rubber plate with a syringe...
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