Medical antibacterial PVC catheter material and preparation method

A PVC resin and catheter technology, applied in the field of biomedical materials, can solve the problems of prone to medical infection accidents, heavy disease burden of patients, repeated infections, etc., and achieve the effects of excellent antibacterial performance, cheap raw materials, and good biocompatibility

Inactive Publication Date: 2016-12-07
胡何辉
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the protective effect of the biofilm, the bacteria in the film will continue to multiply and release planktonic bacteria, causing repeated or worsening infections, and medical infection accidents are prone to occur; medical infecti

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] (1) Weigh 55 parts of PVC resin, 50 parts of high-density polyvinyl chloride, 16 parts of calcium lignosulfonate, 12 parts of linolenic acid, 12 parts of bismaleamic acid, and 10 parts of polymethyl methacrylate , 10 parts of starch octenyl succinate, 8 parts of (3,4-dimethyldibenzylidene) sorbitol, 7 parts of epoxy soybean oil, 5 parts of barium stearate, 4 parts of nano zinc oxide, chitin 4 parts of fiber, 2 parts of sepiolite powder, 1 part of propolis, 3 parts of diisononyl cyclohexane-1,2-dicarboxylate, 3 parts of polyethylene wax;

[0023] (2) Mix calcium lignosulfonate, barium stearate, nano-zinc oxide, chitin fiber, and sepiolite powder, and add them to the ball mill. The speed of the ball mill is 220 r / min. powder, then put the mixed powder into an oven and dry at 120°C to obtain a powdery dry blend;

[0024] (3) Put PVC resin, high-density polyvinyl chloride, bismaleamic acid, polymethyl methacrylate, starch octenyl succinate, (3,4-dimethyl dibenzylidene) sor...

Embodiment 2

[0029] (1) Weigh 60 parts of PVC resin, 55 parts of high-density polyvinyl chloride, 18 parts of calcium lignosulfonate, 13 parts of linolenic acid, 13 parts of bismaleamic acid, and 11 parts of polymethyl methacrylate in parts by weight , 11 parts of starch octenyl succinate, 9 parts of (3,4-dimethyldibenzylidene) sorbitol, 8 parts of epoxy soybean oil, 6 parts of barium stearate, 5 parts of nano zinc oxide, chitin 5 parts of fiber, 3 parts of sepiolite powder, 2 parts of propolis, 4 parts of triethyl citrate, 4 parts of oxidized polyethylene wax;

[0030] (2) Mix calcium lignosulfonate, barium stearate, nano-zinc oxide, chitin fiber, and sepiolite powder, and add them to the ball mill. The speed of the ball mill is 245r / min, and the ball is milled into a powder with a particle size of less than 8 μm. body, and then put the mixed powder into an oven and dry at 135°C to obtain a powdery dry blend;

[0031] (3) Put PVC resin, high-density polyvinyl chloride, bismaleamic acid, ...

Embodiment 3

[0036](1) Weigh 65 parts of PVC resin, 60 parts of high-density polyvinyl chloride, 20 parts of calcium lignosulfonate, 14 parts of linolenic acid, 14 parts of bismaleamic acid, and 12 parts of polymethyl methacrylate in parts by weight , 12 parts of starch octenyl succinate, 10 parts of (3,4-dimethyldibenzylidene) sorbitol, 9 parts of epoxy soybean oil, 7 parts of barium stearate, 6 parts of nano zinc oxide, chitin 6 parts of fiber, 4 parts of sepiolite powder, 3 parts of propolis, 5 parts of tributyl citrate, 5 parts of polyamide wax;

[0037] (2) Mix calcium lignosulfonate, barium stearate, nano-zinc oxide, chitin fiber, and sepiolite powder, and add them to the ball mill. The speed of the ball mill is 270 r / min. powder, and then put the mixed powder into an oven and dry at 150°C to obtain a powdery dry blend;

[0038] (3) Put PVC resin, high-density polyvinyl chloride, bismaleamic acid, polymethyl methacrylate, starch octenyl succinate, (3,4-dimethyl dibenzylidene) sorbit...

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Abstract

The invention discloses a medical antibacterial PVC catheter material which is prepared by taking PVC resin and high density PVC as main components and adding calcium lignosulfonate, linolenic acid, bismaleamic acid, polymethyl methacrylate, octenyl succinic starch ester, (3,4-dimethylbenzylidene) sorbitol, epoxidized soybean oil, barium stearate, nanometer zinc oxide, chitosan fibers, sea-foam stone powder, propolis, a plasticizer and a dispersant under the assistance of processes of ball milling, ultrasonic dispersion, high-temperature stirring, twin-screw extrusion and the like. The prepared catheter material is high in antibacterial performance and biocompatibility, and has considerable mechanical strength and broader application prospect, and the requirement of the industry can be met.

Description

technical field [0001] The invention relates to the field of biomedical materials, in particular to a medical PVC antibacterial catheter material and a preparation method thereof. Background technique [0002] The application of biomedical materials has greatly promoted the rapid development of medical diagnosis and treatment technology. It is a kind of material that is biocompatible with animals and has special properties or functions that can be used for the repair and replacement of animal organs and tissues, diagnosis and treatment of diseases. . Among them, polymer materials have been more and more widely used in the medical field due to their excellent properties, reliable performance, and convenient molding process. First of all, polymer materials have good physical and mechanical properties and chemical stability, which are more suitable for use in the medical field; secondly, polymer materials are rich in sources and low in price, and are suitable for making disp...

Claims

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Application Information

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IPC IPC(8): C08L27/06C08L33/12C08L91/00C08L5/08C08K13/02C08K5/098C08K3/22C08K3/34C08K5/11
CPCC08L27/06C08K2201/011C08L2203/18C08L2205/025C08L2205/035C08L2205/16C08L33/12C08L91/00C08L5/08C08K13/02C08K5/098C08K2003/2296C08K3/346C08K5/11
Inventor 胡何辉
Owner 胡何辉
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