40 results about "Planktonic bacteria" patented technology

The invention discloses an online intelligent monitoring device for dynamic dust particles and floating bacteria in biological cleaning engineering, and relates to the technical field of intelligent monitoring. The device comprises a device body, information modules are arranged on the left and right sides of the inner wall of the device body, an electric sliding rail is arranged at the top of the inner wall of the device body, and a circular groove limiting plate is arranged in the device body through a spring; an anti-interference device is arranged in the electric sliding rail, anti-erosion devices are arranged on the left side and the right side of the anti-interference device, a difference device is arranged below the anti-interference device, the anti-interference device comprises an electric telescopic rod, and the top of the fixed end of the electric telescopic rod is installed in the electric sliding rail in a sliding mode. Different from a traditional detection device which only extracts air at a specified height through horizontal movement for detection, the device solves the problem that the content of dust particles and the content of planktonic bacteria in air at different heights are different, and the detection range is expanded to obtain more accurate monitoring data.

The invention relates to a river ecosystem planktonic bacteria environment threshold identification method, and belongs to the field of environmental ecology and computational biology. The method comprises the following steps: collecting a plurality of environmental factors, fusing and constructing a space-time aligned watershed ecosystem data set, and preprocessing the data set; constructing a prediction model and performing training; environmental factors are collected from a target drainage basin and input into the trained prediction model, and a nonlinear mapping relation between the environmental factors and the microbial community, namely an SHAP value, is obtained through learning; constructing a GAM response curve based on the SHAP values and the environmental factors, fitting a nonlinear response trend of the GAM response curve through a spline function, and identifying an environmental threshold corresponding to each environmental factor; through a Bootstrap resampling method, multiple times of environment threshold recognition are carried out on each environment factor, and a confidence interval is estimated based on environment thresholds obtained through multiple times of recognition, so that the stability and reliability of environment threshold recognition are improved.

The utility model discloses a microorganism collecting and detecting device and relates to the field of planktonic bacteria samplers. The device comprises a base and a device body, a protective shell is arranged on the outer side of the top of the device body, an air suction port is formed in the top of the protective shell, a protective mechanism is arranged on the inner side of the air suction port, and the protective mechanism comprises a fixed blade, an expansion blade and a movable blade. The three groups of fixed blades, expansion blades and movable blades act together to completely cover the opening position of the air suction port in a fan-shaped manner, so that the sampling port is effectively protected, the problem that a traditional detachable cover plate is easy to forget or lose is avoided, the use convenience of the detection device is greatly improved, and the detection efficiency is greatly improved through simple rotating operation. Therefore, the opening and closing of the sampling port can be easily realized, which is convenient and practical.

A rapid detection robot for environmental parameters of a pharmaceutical workshop comprises a mobile platform, and a detection workbench is arranged on the mobile platform; a mechanical arm is installed on the detection workbench, and a culture dish rack used for storing culture dishes is arranged in the working space range of the mechanical arm; the silicon wafer rack is used for storing a silicon wafer bracket; the pipette rack is used for storing a pipette; the pipette tip box is used for storing pipette tips; the centrifugal tube rack is used for storing centrifugal tubes; the uncovering device is used for uncovering operation; the reagent bin is used for storing a probe solution; the planktonic bacteria sampler is used for sampling planktonic bacteria; the shaking incubator is used for culturing planktonic bacteria; the Raman spectrometer is used for carrying out SERS test; the clamp bracket is used for storing the first clamp, the second clamp and the third clamp; the first clamp is used for clamping a culture dish and a silicon wafer bracket, and the second clamp is used for clamping a pipette; the third clamp is used for clamping the centrifugal tube. The invention further discloses a pharmaceutical workshop environment parameter rapid detection method.

The utility model provides a feeding assembly for a planktonic bacteria sampling robot, which belongs to the technical field of planktonic bacteria sampling equipment and comprises a stacking frame, a manipulator and a connecting structure. The stacking frame comprises a bottom plate and a plurality of supporting rods connected to the top of the bottom plate, and each supporting rod is arranged in the height direction; a placing space for placing a culture dish is formed among the plurality of supporting rods; the manipulator is arranged on the sampling workbench; the manipulator is used for grabbing the culture dishes on the stacking frame, and the manipulator can place the culture dishes to a sampling opening of the sampling workbench; the connecting structure is arranged on the sampling workbench; the connecting structure is used for being connected with the bottom plate so as to position the position of the stacking frame; a plurality of culture dishes can be stacked on the stacking frame, the culture dishes on the stacking frame are grabbed through the manipulator, and the culture dishes are placed at the sampling port of the sampling workbench, so that frequent feeding by operators is not needed, and the labor intensity of the operators is reduced.

The utility model discloses a planktonic bacteria sampler, relates to the technical field of samplers, and aims to solve the problems in the prior art that when the planktonic bacteria sampler sucks air and captures planktonic bacteria, the air is inconvenient to screen and filter, large-particle impurities in the air enter the planktonic bacteria sampler, and the cleanness of a culture medium in the planktonic bacteria sampler is influenced. An equipment box is fixedly mounted above the planktonic bacteria sampler body, a filter frame is arranged in the equipment box, the filter frame is composed of a square frame and filter cloth, battens are symmetrically and fixedly mounted in the equipment box along the two sides of the filter frame, insertion grooves are formed in the inner sides of the battens, and the insertion grooves are formed in the inner sides of the battens. The two ends of the filtering frame are inserted into the inserting grooves of the two battens correspondingly, a sealing plate groove hole is formed in the front end face of the equipment box, a sealing plate is arranged in the sealing plate groove hole, and the sealing plate is fixedly connected with the square frame.

The invention discloses a gallium metal organic framework material which is prepared by the following steps: (1) dissolving 2-aminoterephthalic acid and itaconic acid in an organic solvent to obtain a solution A; (2) dissolving gallium nitrate hydrate in an organic solvent to obtain a solution B containing gallium ions; and (3) mixing the solution A with the solution B, heating at 50-70 DEG C for 3-5 hours, centrifuging, collecting the precipitate, and purifying to obtain the product. Itaconic acid and 2-aminoterephthalic acid are combined as double ligands, gallium ions are used as metal nodes, the gallium metal organic framework material is jointly constructed, the technical problems that itaconic acid in a free form is short in biological half-life period and low in cellular uptake efficiency are solved, the itaconic acid and the gallium ions are coordinated to achieve anti-inflammatory and antibacterial effects, and the gallium metal organic framework material has good application prospects. The compound can remove planktonic bacteria, has strong anti-biofilm activity, and can be used for preparing drugs for treating suppurative arthritis.

The invention discloses a planktonic bacteria sampling method, device and equipment, a medium and a product, and relates to the technical field of planktonic bacteria sampling, the method comprises the following steps: obtaining at least one preset sampling point position and task mode, and generating a sampling task; sequentially moving to each sampling point position, sampling floating bacteria at the sampling point position according to the sampling task to obtain a sampling result, and enabling the direction of a sampling air inlet to face away from the current air flow direction; and outputting a sampling result to a preset remote server and local storage equipment. According to the application, the sampling consistency and the automation and informatization degree of the floating bacteria are improved.

The utility model relates to the technical field of planktonic bacteria, and discloses a split planktonic bacteria sampler which comprises a base, a mounting plate is mounted on the upper portion of the base, a support is movably sleeved with the side face of the mounting plate, and a limiting plate for limiting the position of the support is mounted on the upper portion of the mounting plate. The top end of the support is movably provided with a detection device main body, the interior of the detection device main body is fixedly connected with a transverse plate, and the exterior of the upper end of the transverse plate is provided with eight groups of sliding rods at equal intervals. According to the split type planktonic bacteria sampler, the position of the detection device main body is driven to be limited through the bracket, and the bracket can be mounted at the upper part of the mounting plate and is fixed through the limiting plate, or the bracket can be freely moved to different areas after being detached from the outside of the mounting plate, so that in the planktonic bacteria collecting process, the planktonic bacteria can be conveniently collected; the main body of the detection device is designed in a split manner and can be moved to a narrow area to collect the floating bacteria, so that the floating bacteria collection efficiency and convenience are improved.

An improved formulation may include an enhanced ability relative to its predicates to destroy toxic threats in the form of sporulated bacteria, bacteria protected by biofilms, planktonic bacteria, fungus, viruses, chemical weapons, toxic chemicals including Fentanyl, its analogs, and a whole host of toxic industrial chemicals. The formulation may include a three part product composed of a buffered detergent chemical system, a hydrogen peroxide chemical system and an accelerator system designed to deliver activated peroxygen species when blended together.

The utility model belongs to the technical field of biological evaluation of medical instruments, and particularly relates to a wound biological membrane culture system and a dynamic in-vitro wound model for antibacterial activity evaluation, which comprise a culture medium dripping system, a reactor and a waste liquid collecting bottle which are sequentially connected, according to the utility model, the glass slide and the in-vitro pigskin tissue or the glass slide and the in-vitro pigskin tissue, the test dressing and the balancing weight are sequentially arranged in the test bin of the reactor from bottom to top. The in-vitro pigskin tissue is used for wound surface construction and microbial inoculation, continuous nutrition supply is provided, the in-vitro pigskin tissue in-vitro biological membrane preparation device can be used for preparing a wound surface biological membrane, planktonic bacteria infection or biological membrane infection of the wound surface can be simulated, the in-vitro pigskin tissue in-vitro biological membrane preparation device is closer to the actual clinical condition, and the antibacterial activity of the antibacterial wound surface dressing can be predicted more accurately.

A composition comprising a 2-hydroxycarboxylic acid for deactivating the metabolism of planktonic bacteria and uses thereof.

The invention relates to a pseudomonas aeruginosa bacteriophage and application thereof, the pseudomonas aeruginosa bacteriophage PA75 has the preservation number as follows: the bacteriophage has strong tolerance to high temperature and acid-base, can effectively split pseudomonas aeruginosa, does not contain antibiotic resistance genes and virulence factors in a genome, and is safe and reliable. The bacteriophage PA75 provided by the invention not only can enrich a germplasm resource library of the pseudomonas aeruginosa bacteriophage, but also can provide a selectable basic material for biological prevention and control of the pseudomonas aeruginosa; the bacteriophage can effectively inhibit the growth of planktonic bacteria in a relatively short time, can be used for daily disinfection of the surfaces of medical apparatuses and instruments and hospital environments especially in medical environments in which drug-resistant bacteria generally exist and common disinfectants have poor effects, and is high in safety coefficient and wide in application range.

The present application relates to a kind of river planktonic bacteria community composition prediction method based on artificial neural network auto-encoder, belong to environmental science field.The method is by collecting river planktonic bacteria OTU relative abundance and related water environment, meteorological data etc., form original data set, and carry out pre-processing.Using auto-encoder model, the potential space based on OTU composition and the potential space based on environmental elements are constructed by training set, the difference between the two potential spaces is minimized during training, and OTU composition is obtained from potential space by the same decoder.Using SHAP value to explain the model, understand how each environmental factor affects the model prediction of a single sample, and understand the overall impact of environmental factors on model prediction by averaging the SHAP values of multiple samples.The present application explores the change relationship between various environmental factors and river planktonic bacteria relative abundance from the perspective of data-driven deep learning model.

Compositions comprising 2-hydroxycarboxylic acid for dysregulating the metabolism of planktonic bacteria and their use. This disclosure provides compositions for dysregulating the metabolism of planktonic bacteria, the compositions comprising preferred enantiomers of 2-hydroxycarboxylic acid. This disclosure further provides compositions for dysregulating the metabolism of planktonic bacteria, the compositions comprising preferred enantiomers of 2-hydroxycarboxylic acid and antimicrobial compounds. Dysregulation of the metabolism of planktonic bacteria can be measured, among other examples, by a decrease in the MIC of concomitant antimicrobial agents, an enhancement of in vivo antimicrobial effects, or aerobic respiration of metabolically active cells (reduction of non-fluorescent resazurin to highly fluorescent resorphine), which can lead to sensitization of planktonic bacteria to antimicrobial compounds and / or disruption of resistance of planktonic bacteria to antimicrobial compounds.

The utility model discloses an automatic tester for planktonic bacteria, relates to the technical field of the automatic tester for planktonic bacteria, and provides the following scheme: the automatic tester for planktonic bacteria comprises a base, a damping bearing is mounted at the top of the base, a mounting disc is mounted on the outer side of the damping bearing, and an adjusting block is mounted on the outer side of the mounting disc; a rotary knob is fixed to the middle of the adjusting block, a clamping mechanism is annularly arranged on the periphery of the mounting disc, a mounting base is mounted on the front side of the mounting disc, a testing box is fixed to the front side of the mounting base, magnetic attraction pieces are symmetrically fixed to the two sides of the base, and connecting bolts penetrate through the middles of the magnetic attraction pieces. The magnetic suction sheet is fixed on the outer side of the base through a connecting bolt; by arranging the clamping mechanism, the mounting disc and the mounting base are stably connected to be clamped and fixed, no tool is needed for disassembly, equipment is small and flexible, disassembly and assembly are convenient and fast, it is guaranteed that the device can be disassembled, assembled and moved according to needs when floating bacteria are detected, meanwhile, disassembly and overhaul can be conveniently conducted, and maintenance operation is facilitated.

The utility model provides an air planktonic bacteria sampler which comprises a main machine and a plurality of sampling seats, the main machine and the plurality of sampling seats are respectively provided with an annular table with an extraction opening, an inner cavity of the main machine is provided with a fan communicated with the extraction opening, and the annular tables are detachably provided with trays for placing culture dishes. Each sampling seat is provided with a communicating pipe communicated with the corresponding extraction opening, the annular table is detachably sleeved with an end cover with a plurality of micropores, the annular table located on the main machine is detachably sleeved with a collecting cover with a collecting pipe, and the collecting cover is provided with a communicating assembly used for communicating the communicating pipes; after a fan drives air to vibrate through micropores in an end cover, particles fall into a culture dish to be sampled, the end cover on a main machine is replaced by a collecting cover, and the collecting cover is communicated with a plurality of communicating pipes through a communicating assembly, so that sampling work at multiple positions can be carried out at the same time, the sampling efficiency is improved, sampling can be carried out in multiple narrow spaces, and the sampling efficiency is improved. Multiple sampling working modes are provided, and multiple sampling requirements are met.

Compositions, methods, and kits are provided for treating bacterial infections with nanoclusters comprising a metallic core conjugated to a nucleotide. Recalcitrant infections are often difficult to treat because of the presence of persister cells, a subpopulation of bacterial cells that is highly tolerant of traditional antibiotics. Persister cells are dormant, which makes them less susceptible to many antibiotics, which are designed to kill growing cells. Administration of nanoclusters comprising a nucleotide was found to be highly efficacious in eradicating persister cells and for treating infections for a broad range of bacterial species, including Gram-positive and Gram-negative bacteria. Such treatment was effective not only in eradicating planktonic bacteria but also bacteria in biofilms.

The invention provides an operation site environment intelligent control method which comprises the following steps: identifying planktonic bacteria concentration distribution of a local planktonic bacteria concentration increasing area, and performing clustering grouping processing on a planktonic bacteria concentration distribution diagram according to the planktonic bacteria concentration to obtain a boundary coordinate and a center point position of a high-concentration area; according to the concentration change of planktonic bacteria in the high-concentration area and the proportion of the air flow covering the high-concentration area, the filtering strength level is enhanced so as to meet the purification requirement of the high-concentration area; integrating the updated filtering strength level and airflow path configuration, simulating the overall purification efficiency change of the operation site environment, and judging whether the simulated purification efficiency reaches a preset standard value or not; if the preset standard value is not reached, the airflow path vector and the filtering intensity level are iteratively adjusted according to deviation analysis of the simulated purification efficiency, and finally optimized purification equipment control parameters are obtained.

The application discloses a bacterial biofilm detection probe, a detection method and application, relates to the technical field of microorganism detection and fluorescent probe application, and the fluorescent probe is of formula Ia structure. The bacterial biofilm detection probe detection method comprises the following steps: bacterial culture to form a biofilm, PBS removal of planktonic bacteria, addition of the probe incubation for 5 min, and detection of 520 nm fluorescence intensity by using a fluorescence enzyme label instrument. The application applies the fluorescent probe to biofilm detection, compared with traditional classic biofilm detection methods such as crystal violet, has the advantages of no need of cleaning, short detection period, simple operation, high accuracy, strong linear correlation, adaptation to gram-positive / negative bacteria and fungal biofilm, and provides an effective tool for detection of bacterial biofilm. The application can be used for high-throughput screening of active drugs with inhibition of biofilm formation or destruction of bacterial biofilm structure, and solves the technical problems of complicated steps, long time consumption and poor reproducibility in the prior art.

The utility model provides a remote sampling assembly. The remote sampling assembly comprises an adapter, a remote sampling head and a straight-through connecting pipe, the adapter is used for being connected with a sampling head mounting interface on a planktonic bacteria sampler, and an air inlet is formed in the adapter; the remote sampling head is provided with a sampling port, a first air outlet pipe and a second air outlet pipe, the first air outlet pipe and the second air outlet pipe are communicated with the sampling port, the first air outlet pipe extends in the axial direction of the sampling port, and the second air outlet pipe extends perpendicular to the axial direction of the sampling port and has a horizontal flow sampling form and a vertical flow sampling form; the other end of the straight-through connecting pipe is connected with the first air outlet pipe or the second air outlet pipe; when the straight-through connecting pipe is connected with the first air outlet pipe, the remote sampling head forms a horizontal flow sampling form, and when the straight-through connecting pipe is connected with the second air outlet pipe, the remote sampling head forms a vertical flow sampling form. The utility model further provides a planktonic bacteria sampler adopting the remote sampling assembly, and direct-current remote sampling and horizontal-flow remote sampling can be achieved.

The invention belongs to the technical field of nano-drugs, and particularly relates to multifunctional honokiol nano-particles and a preparation method and application thereof.The honokiol nano-particles are prepared by using rhamnolipid modified chitosan as a carrier and loading honokiol; according to the nano-particles, an amido bond formed between rhamnolipid and chitosan can be subjected to targeted decomposition under the acidic condition of a bacterial infection part, and the released rhamnolipid can destroy a bacterial biofilm; further, permeation of the natural antibacterial agent honokiol and chitosan at the infected part is enhanced, and synergistic sterilization is realized; meanwhile, the planktonic bacteria re-adhesion resistance characteristic of rhamnolipid can inhibit the re-formation of a biofilm, the full-stage sterilization of'destroying the biofilm, killing bacteria in the film and inhibiting the re-adhesion of residual bacteria 'of the nanoparticles is finally realized, and the multifunctional honokiol nano platform is suitable for preventing and treating infectious diseases such as wound infection and bacterial peritonitis.

The embodiment of the utility model relates to the technical field of refrigeration, in particular to a refrigerator. According to the ion generator disclosed by the embodiment of the invention, the plasma is generated by arranging the opposite electrode group, so that the effect of sterilizing the refrigerating chamber can be achieved, and the plasma can also decompose peculiar smell molecules to achieve the purification effect. The third electrode is arranged outside the area of the opposite electrode set and used for generating the air negative ions, the air negative ions adsorb the planktonic bacteria in the refrigerating chamber, and the effect of removing the planktonic bacteria is achieved. According to the ion generator, the plasma can be generated, the air negative ions can also be generated, the plasma and the air negative ions are complementary, and the sterilization and odor removal effects on the refrigerating chamber are improved.

The invention discloses a novel planktonic bacteria sampling head which comprises a bottom plate, an air exhaust hole is formed in the middle of the bottom plate, a fan is arranged below the air exhaust hole, a mounting seat is arranged above the air exhaust hole, a culture dish is placed on the mounting seat, at least three movable fixed clamping jaws are arranged on the periphery of the mounting seat, and the fixed clamping jaws are arranged on the mounting seat. At least three movable fixed clamping jaws are matched to fix a culture dish, a sampling distribution plate is arranged above the culture dish, the sampling distribution plate is connected with an outer protective shell, the outer protective shell covers the periphery of the mounting seat and is in sealed connection with the bottom plate to form a sampling space, and an air exhaust hole is in through connection with the sampling space; the fan pumps air in the sampling space away from the exhaust hole, and the sampling distribution plate is used for uniformly diffusing external air to the culture dish. The device can adapt to multiple types of culture dishes, and is convenient and reliable to operate.

The utility model relates to the field of planktonic bacteria samplers, and discloses a flow calibrating device of a planktonic bacteria sampler, which comprises an electronic flowmeter and a connecting mechanism, one side of the front end of the electronic flowmeter is fixedly provided with a placing plate, the connecting mechanism comprises a mounting block and a fixing pipe, the middle position of the upper end of the mounting block is rotatably provided with a rotating column, and the rotating column is fixedly connected with the electronic flowmeter. A telescopic pipe is fixedly arranged at the front end of the fixed pipe, a first connecting pipe is fixedly arranged at the front end of the telescopic pipe, a connecting seat is fixedly arranged at the lower end of the first connecting pipe, a bearing is rotationally arranged at the position, close to the telescopic pipe, of the outer side of the fixed pipe, and a movable pipe is fixedly arranged at the inner end of the bearing. According to the utility model, when a plurality of planktonic bacteria samplers need to be measured in sequence, the movable pipe can be rotated to connect the flange with the exhaust hole of another planktonic bacteria sampler, the valve of the fixed pipe is closed, and the valve of the movable pipe is opened, so that the time of repeated measurement is shortened, and continuous flow measurement by a user is facilitated.

The utility model discloses a planktonic bacteria sampler flow regulating device which comprises a base, a regulating tank and a buffer tank are respectively arranged at the top of the base close to two ends, one end of the regulating tank and one end of the buffer tank are respectively provided with a mounting joint, the other end of the regulating tank is connected with the other end of the buffer tank through a connecting pipe, and a rotor flow meter is arranged at the top of the connecting pipe. A control mechanism facilitating flow adjustment is arranged on the inner side of the adjusting tank, and one-way valves are installed at the positions, close to the two ends, of the buffer tank. Gas flow in the adjusting tank can be adjusted through the arranged control mechanism, and the gas flow can be monitored in real time through the arranged rotor flow meter; and the buffer tank and the one-way valve in the buffer tank play roles in stabilizing the gas flow and preventing the gas from flowing back, so that through the structure, the precise and stable control on the gas flow of the planktonic bacteria sampler is realized, and the accuracy and reliability of sampling data are ensured.

The utility model provides a biosafety cabinet of a multifunctional monitoring system, which relates to the technical field of biosafety cabinets and comprises an outer container, an inner container is arranged in the outer container, a threaded connector is welded on the side wall of the inner container, one end of the threaded connector is connected with a first bent pipe, the other end of the threaded connector is connected with a second bent pipe, and the first bent pipe and the second bent pipe are welded together. The second bent pipe is connected with a planktonic bacteria collector; a third bent pipe is inserted into the side wall of the inner container, and one end of the third bent pipe is connected with a microparticle collector; an operation table is arranged at the bottom of the inner container, a planktonic bacteria monitoring channel and a microparticle monitoring channel are arranged on the inner wall of the inner container, and a glass door is arranged on the front wall of the inner container. The microparticle collection channel and the planktonic bacteria collection channel are arranged, samples in the cabinet can be collected outside the cabinet and transmitted to the controller, the influence of the collector on a working area is reduced, and the samples can be effectively collected while normal work is achieved.

The utility model relates to the technical field of samplers, and discloses a planktonic bacteria biological sampler which comprises a sampler main body and a placing table arranged at the top of the sampler main body, and further comprises a connecting shell in threaded connection with one side of the surface of the placing table, and a rotating shell is rotationally connected with the inner wall of the connecting shell; a mounting plate is rotationally connected to the inner wall of the rotating shell, a ventilation opening is formed in the center point of the mounting plate, and a ventilation plate is bolted to the inner wall of the ventilation opening; through the cooperation of the rotating shell, the isosceles hexagonal groove, the blocking mechanism and the sliding groove, the situation that the sampler cannot be sealed when the sampler is not used due to the fact that the blocking cover is lost or damaged when the sampler is used is prevented, and under the action of the cleaning mechanism, the sampler is prevented from being damaged when the sampler is used for a long time. And under the cooperation of an inflation pipe and a one-way valve, the cleaning mechanism can be inflated, so that subsequent use is facilitated.

The utility model discloses a clean room environment monitoring system, this system includes the LIMS system of installation on industrial server, environmental monitoring instrument, data acquisition module, data concentrator and controlled equipment, environmental monitoring instrument includes the dust particle sampling counter and planktonic bacteria sampling counter through pipeline and the connection of air extraction system, the LIMS system has integrated experiment reservation and data analysis function module, is used to receive environmental data and carries out analysis and judgment, and then generates instruction control controlled equipment, industrial server carries out data interaction with data concentrator, and through wired or wireless network and remote control component two -way communication connection. The utility model discloses through real -time monitoring and intelligent analysis and judgment, has realized clean room environment's all -round, intelligent, pre -judgment formula monitoring and guarantee, has avoided experiment pollution risk effectively, and has reached the effect of energy -conserving and loss -reducing.

The application discloses a gallium metal organic framework material, which is prepared through the following steps: (1) dissolving 2-amino terephthalic acid and itaconic acid in an organic solvent to obtain solution A; (2) dissolving gallium nitrate hydrate in an organic solvent to obtain solution B containing gallium ions; and (3) mixing solution A and solution B, heating under the condition of 50-70 DEG C for 3-5 hours, centrifuging and collecting the precipitate, and purifying to obtain the gallium metal organic framework material. The gallium metal organic framework material is constructed by combining itaconic acid and 2-amino terephthalic acid as a double ligand and taking gallium ions as a metal node, so that the technical problems of short biological half-life and low cell uptake efficiency of free itaconic acid are solved, the itaconic acid and the gallium ions are coordinated to play an anti-inflammatory and antibacterial role, to remove planktonic bacteria, and to have strong antibiofilm activity, and the gallium metal organic framework material can be used for preparing a drug for treating pyogenic arthritis.