Method for preparing 2,5-furandicarboxylicacid (FDCA) by catalytic carbonylation

Abstract

The invention discloses a method for preparing 2,5-furandicarboxylicacid (FDCA) by catalytic carbonylation. The method comprises the following steps: taking 5-bromo-2-furoic acid as a raw material, carrying out stirring reaction on a reaction system which simultaneously contains 5-bromo-2-furoic acid, solvent, alkali and palladium catalyst under the atmosphere of carbonic oxide at the temperatureof 50-120 DEG C for 4-20h; then, removing the solvent, adding acidified reagent to regulate a pH (Potential of Hydrogen) value to acidity, and separating a target product FDCA, wherein the palladium catalyst contains a palladium element, the solvent is water or a mixture of water and organic solvent. According to the method, the 5-bromo-2-furoic acid is taken as the raw material, and the whole technical process design of the preparation method and the reaction condition and parameter (including the category and the ratio of reaction raw materials, reaction temperature, time and the like) of each step can be improved. Compared with the prior art, the method disclosed by the invention solves the problem that human grain resources which need to be consumed for preparing FDCA is solved.

Description

technical field [0001] The invention belongs to the field of organic catalysis, and more specifically relates to a method for preparing 2,5-furandicarboxylic acid by catalytic carbonylation, which provides a new way for the preparation of 2,5-furandicarboxylic acid. Background technique [0002] The gradual depletion of petroleum resources has caused a huge impact on the petroleum-based chemical industry and even affected the development of the national economy. Terephthalic acid (PTA) has always been a bulk chemical with great market demand. Domestic PTA production capacity has soared from about 15 million tons in 2010 to nearly 46 million tons in 2015, accounting for about half of the global production capacity, of which 90% The above PTAs are all used in the production of polyester. In order to solve the crisis caused by the depletion of petroleum resources, the search for petroleum substitutes has attracted much attention, and biomass resources, which have the advantage...

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Problems solved by technology

[0005] In view of the defects that most of the current methods of preparing FDCA use food-based C6 sugars as raw materials to compete with humans for the already tight food resources, the purpose of the present invention is to provide a method for preparing 2,5-furandicarboxylic acid by catalytic carbonylation , wherein by using 5-bromo-2-furoic acid as a raw material, and improving the overall process flow design of the preparation method, as well as the reaction conditions and parameters of each step (including the type and proportion of reaction raw materials, reaction temperature and time, etc.) Compared with the prior art, it can effectively solve the problem that the preparation of FDCA needs to consume human food resources. The present invention uses furfural derivative 5-bromo-2-furoic acid as raw material, and the C5 sugar for synthesizing the raw material originally comes from abundant and Renewable agricultural and forestry waste such as straw, sawdust, etc., so the present invention can effectively achieve "not competing with people for food or land with food" by changing the source of FDCA synthesis route, and also broadens the biomass of furfural-based C5 platform The molecular market makes its downstream products more diversified; and, the present invention ensures high reaction parameters by optimizing reaction parameter conditions (such as the type and proportion of reaction raw materials, reaction temperature and time, carbon monoxide initial pressure value, etc.). Efficiency and product selectivity, mild reaction conditions, easy operation, great application value and prospects

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