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Composition containing sea cucumber compound polysaccharide powder, compound preparation, and application of composition

A technology of complex polysaccharides and compositions, which is applied in the field of series sea cucumber compound preparations and its preparation, can solve the problems that sea cucumbers cannot be completely absorbed and utilized by the human body, the clinical effect of support is unclear, and stay in a relatively primary stage, so as to achieve the reduction of capillary Fragility, strength and healing, resistance-enhancing effects

Pending Publication Date: 2021-05-04
三亚海王海洋生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] At present, the majority of people still take sea cucumbers as food supplements. This way of taking sea cucumbers will not be fully absorbed and utilized by the human body, and the utilization rate of sea cucumbers is low. At the same time, in the traditional processing technology, the loss of sea cucumbers is relatively large
[0011] In addition, it is reported that the hypoglycemic effect of sea cucumber oligopeptides on alloxan-induced diabetic mice, such as intraperitoneal injection of alloxan to create a mouse model of diabetes, and different doses of sea cucumber oligopeptides (0.1 , 0.2, 0.5g / kg), recorded intragastric administration (Wang Zumapu, Zuo Aihua, Research on the hypoglycemic effect of sea cucumber oligopeptides on diabetic mice, Food Research and Development. 2019-08 No. 85-90 Page), other literatures have also reported its blood lipid-lowering effect, but all these studies are still at a relatively early stage, in the preclinical research stage, whether it can certainly support the clinical effect is not clear, and it is specific to sea cucumber polypeptides, polysaccharides, and lipids Although ingredients such as TCM have certain hypoglycemic and blood lipid-lowering effects, the ingredients are single and not compound ingredients, but it is obvious that the yield of specific active ingredients in traditional Chinese medicine is low, the preparation cost is high, and whether it can be orally absorbed is still unclear. Using these active ingredients may have certain side effects

Method used

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  • Composition containing sea cucumber compound polysaccharide powder, compound preparation, and application of composition
  • Composition containing sea cucumber compound polysaccharide powder, compound preparation, and application of composition
  • Composition containing sea cucumber compound polysaccharide powder, compound preparation, and application of composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0056] Example 1 Sea cucumber hypoglycemic compound preparation formula and preparation process

[0057] 1) Preparation of sea cucumber hypoglycemic tablets

[0058] A: 200g sea cucumber compound polysaccharide protein powder, 10g yam, 10g lily, 10g medlar, 10g mulberry leaf, 10g seabuckthorn, 150g kudzu root, 100g xylitol (or stachyose), 100g fructooligosaccharide, 390g maltodextrin, Magnesium stearate 10g; put sea cucumber compound polysaccharide protein powder, yam, lily, wolfberry, mulberry leaves, seabuckthorn, kudzu root, xylitol (or stachyose), fructooligosaccharides, and maltodextrin into the mixer according to the formula Mix evenly (mix for about 15 minutes), add ethanol to make a soft material, put the soft material into a granulator for granulation, and pass through a 24-mesh sieve to crush and granulate; air-dry at 50°C for 6 hours, and the moisture content is controlled at 5 % or so; pass through a 20-mesh sieve for granulation; mix the granulated granules with ...

Embodiment 2

[0065] Embodiment 2 Sea cucumber hypolipidemic compound preparation formula and preparation process

[0066] 1) Sea Cucumber Blood Lipid Tablets

[0067] A: 200g sea cucumber compound polysaccharide protein powder, 50g lotus leaf, 50g chicory, 50g sophora, 100g kudzu root, 50g hawthorn, 50g xylitol (or stachyose), 50g fructooligosaccharide, 390g maltodextrin, stearic acid Magnesium 10g; preparation method is the same as sea cucumber hypoglycemic tablets. (Sample batch number: 20190801)

[0068] B: Sea cucumber compound polysaccharide protein powder 300g, lotus leaf 100g, chicory 100g, sophora japonica 100g, kudzu root 150g, hawthorn 100g, xylitol (or stachyose) 50g, fructooligosaccharides 50g, maltodextrin 40g, stearic acid Magnesium 10g; preparation method is the same as sea cucumber hypoglycemic tablets. (Sample batch number: 20190802)

[0069] C. Sea cucumber compound polysaccharide protein powder 250g, lotus leaf 75g, chicory 75g, pagoda japonica 75g, kudzu root 125g, ...

Embodiment 3

[0074] Embodiment 3 formula and preparation technology of sea cucumber enhanced immunity compound preparation

[0075] 1) Sea Cucumber Aphrodisiac Enhancement Immunity Tablet (pressed candy)

[0076] A: Sea cucumber compound polysaccharide protein powder 200g, oyster powder 200g, Yizhiren 10g, sealwort 100g, xylitol (or stachyose) 50g, fructooligosaccharides 50g, maltodextrin 380g, magnesium stearate 10g; preparation method Same as sea cucumber hypoglycemic tablets. (Sample batch number: 20190901)

[0077] B: Sea cucumber compound polysaccharide protein powder 300g, oyster powder 300g, Yizhiren 50g, sealwort 200g, xylitol (or stachyose) 50g, fructooligosaccharides 50g, maltodextrin 40g, magnesium stearate 10g; preparation method Same as sea cucumber hypoglycemic tablets. (Sample batch number: 20190902)

[0078] C: Sea cucumber compound polysaccharide protein powder 250g, oyster powder 250g, Yizhiren 25g, sealwort 150g, xylitol (or stachyose) 50g, fructooligosaccharides 50g...

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Abstract

The invention provides a sea cucumber composition compound preparation and application of the sea cucumber composition compound preparation. The invention provides a blood glucose reduction composition containing sea cucumber compound polysaccharide protein powder, and the composition is prepared from an active ingredient and an auxiliary material, wherein the active ingredient consists of the sea cucumber compound polysaccharide protein powder, rhizoma dioscoreae, bulbus lilii, fructus lycii, folium mori, fructus hippophae and radix puerariae lobatae. The invention provides a blood fat reduction composition containing the sea cucumber compound polysaccharide protein powder, and the blood fat reduction composition is prepared from the active ingredient and the auxiliary material, and the active ingredient consists of the sea cucumber compound polysaccharide protein powder, folium nelumbinis, herba cichorii, flos sophorae immaturus, radix puerariae lobatae and fructus crataegi. The invention provides a composition which contains the sea cucumber compound polysaccharide powder and is capable of tonifying Yang and boosting immunity, and the composition is prepared from the active ingredient and the auxiliary material, wherein the active ingredient consists of the sea cucumber compound polysaccharide protein powder, ostrea gigas tnunb powder, fructus alpiniae oxyphyllae and rhizoma polygonati. The invention carries out collocation according to own functional characteristics, and has the serial functions of reducing the blood sugar, reducing the blood fat and boosting the immunity.

Description

technical field [0001] The invention belongs to the technical field of medical care and new drug development, and discloses a series of sea cucumber compound preparations containing sea cucumber compound polysaccharide powder and a preparation method thereof, which have the functions of lowering blood fat, lowering blood sugar and enhancing immunity. Background technique [0002] Sea cucumbers are all of sea cucumbers of the family Aposticidae or other species of sea cucumbers. After the sea cucumber is caught, remove the viscera, wash the silt in the cavity, boil it in appropriate salt water for about 1 hour, pick it up and let it cool, expose it to the sun or bake it until it is 80% to 90% dry, then put it in the liquid of the leaves and boil it for a while , When the color turns black, take it out and dry it in the sun. Function cures mainly: nourishing the kidney and replenishing essence, nourishing blood and eliminating dryness. Treatment of deficiency of essence and ...

Claims

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Application Information

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IPC IPC(8): A61K36/8967A61K35/616A61P3/10A61P15/00A61P37/04A23L33/10
CPCA23V2002/00A61K35/616A61K36/185A61K36/488A61K36/605A61K36/815A61K36/8945A61K36/8967A23L33/10A61P3/10A61P15/00A61P37/04A61K2300/00A23V2200/328A23V2200/324A23V2200/30
Inventor 严启新曾琪陈平原刘霞王璐刘程程
Owner 三亚海王海洋生物科技有限公司
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