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Lupin total extract consisting of a lupin sugar extract and a lupin peptide extract, method for the production and use thereof

A technology of extract and lentil sugar, applied in the field of compositions, can solve the problems of increased fecal lipase and protease activity, skin irritation, increased pH and the like

Inactive Publication Date: 2007-05-09
LAB EXPANSCIENCE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Especially in diaper rash, the formation of ammonia is not the direct cause of erythema, but causes an increase in pH, which promotes an increase in fecal lipase and protease activity, resulting in skin irritation

Method used

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  • Lupin total extract consisting of a lupin sugar extract and a lupin peptide extract, method for the production and use thereof
  • Lupin total extract consisting of a lupin sugar extract and a lupin peptide extract, method for the production and use thereof
  • Lupin total extract consisting of a lupin sugar extract and a lupin peptide extract, method for the production and use thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 2

[0117] Embodiment 2: the preparation method of the total lentil extract described in the present invention

[0118] A) the preparation method of lentil sugar extract

[0119] a) Delipidize with ethanol

[0120] 9.9 kg of lentil flour and 85 L of ethanol were mixed together, and the mixture was stirred at room temperature for 1 hour. The mixture was then placed in a decanter and the ethanol component was removed.

[0121] a) recovery of sugar components:

[0122] i) Disperse in water and adjust pH

[0123] 90 L of water was added to the decanted fraction, and the pH value was adjusted to 8.5 with alkali.

[0124] ii) Centrifuge and filter with a plate filter

[0125] The solution thus obtained was centrifuged on a Westfalia type continuous decanter and then filtered on a plate filter. Collect the filtrate.

[0126] iii) Ultrafiltration and concentration with a 10kDa critical threshold membrane

[0127] The filtrate concentration factor was 2. Then use 2 volumes of soft...

Embodiment 3

[0153] Example 3: Formulation for preventing and / or treating diaper rash:

[0154] Purified water 56.6%

[0155] Zinc Oxide 10.0%

[0156] Caprylyl Glycol 5.0%

[0157] Fluid Petrolatum 5.0%

[0158] Propylene Glycol Octanoate 4.0%

[0159] Methyl Glucose Dioleate 4.0%

[0160] Organophilic Titanium Dioxide 3.0%

[0161] Copolymer PEG-45 / Lauryl Glycol 3.0%

[0162] Microcrystalline Wax 2.0%

[0163] Total lentil extract 2.0%

[0164] D-Amyl Alcohol 2.0%

[0165] 35% Natural Vitamin F 1.0%

[0166] Elderberry Oil 1.0%

[0167] Potassium sorbate 0.5%

[0168] Methylparaben 0.3%

[0169] Magnesium Sulfate 0.3%

[0170] Propylparaben 0.3%

[0171] Genistein 0.10%

Embodiment 4

[0172] Embodiment 4: formula for washing milk for personal hygiene

[0173] Composition %w / w

[0174] Water QSP 100

[0175] Coco-glucoside 10.00

[0176] Disodium Lauryl Sulfosuccinate 2.00

[0177] Sodium Cocoyl Isethionate 2.00

[0178] Cornstarch 2.00

[0179] Cetyl Alcohol 2.00

[0180] Hydroxypropyl Guar Gum 2.00

[0181] Citric Acid QS pH

[0182] Total lentil extract 0.1-10

[0183] Genistein 0.1-10

[0184] Glycerin 0.45

[0185] Polyquaternium 10 0.30

[0186] EDTA (ethylenediaminetetraacetic acid) tetrasodium 0.20

[0187] Titanium dioxide 0.10

[0188] Preservative QS

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Abstract

The invention relates to a composition comprising a lupin total extract consisting of a lupin sugar extract, comprising at least 50 % galactooligosacharides by weight, in relation to the weight of dry matter, and a lupin peptide extract. The composition can also contain a chromane derivative or a chromene derivative. The invention also relates to a pharmaceutical and / or cosmetic composition comprising said lupin total extract, used advantageously as an anti-inflammatory agent, which repairs the cutaneous barrier and heals, used particularly in the prevention and / or treatment of erythemas.

Description

technical field [0001] The present invention relates to a composition containing a lentil sugar extract and a lentil peptide extract rich in galacto-oligosaccharides. The composition can be used as an anti-inflammatory drug to repair skin barriers and wounds, especially for preventing and / or treating erythema accompanied by ruptured or unruptured skin barriers. Background technique [0002] Diaper rash is a skin disease that occurs frequently in babies. More than 50% of infants suffer from this disease, and the incidence rate is 25% within four weeks after birth, with a peak from September to December. This is due to damage to the stratum corneum of the skin on the baby's buttocks for two reasons: [0003] - impregnation of diapers activates urinary and fecal enzymes, [0004] - The abrasive effect of the diaper rubbing against the skin. [0005] In infancy, urine is only a minor irritant to the skin. Investigations of breastfed infants have shown that irritation is mai...

Claims

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Application Information

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IPC IPC(8): A61K8/97A61K36/48A61Q19/00A61Q17/00A61K8/64A61K8/73
CPCA61K8/645A61K8/73A61K8/97A61Q17/00A61Q19/00A61Q19/004A61K8/64A61K36/48A61Q19/08A61K8/9789A61P17/00A61P29/00
Inventor J·C·舒络特A·皮奇雷利N·皮卡尔迪P·姆西卡F·保罗
Owner LAB EXPANSCIENCE
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