Wear resistant antimicrobial compositions and methods of use

a technology of antimicrobial compositions and compositions, applied in the field of antimicrobial compositions, can solve the problems of difficult elimination, health hazards of microorganisms, and increased risk of individual microorganisms, and achieve the effect of improving wear resistan

a technology of antimicrobial compositions and compositions, applied in the field of antimicrobial compositions, can solve the problems of difficult elimination, health hazards of microorganisms, and increased risk of individual microorganisms, and achieve the effect of improving wear resistan

US20120148751A1Inactive Publication Date: 2012-06-14ECOLAB USA INC

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  • Wear resistant antimicrobial compositions and methods of use
  • Wear resistant antimicrobial compositions and methods of use
  • Wear resistant antimicrobial compositions and methods of use

Examples

Experimental program
Comparison scheme
Effect test

example 1

Hard Surface Efficacy of PHMB / Quaternary Ammonium Chloride Blend Vs. Stabilized Chlorine Dioxide

[0176]The objective of this analysis was to examine the efficacy of various compositions against Staphylococcus aureus ATCC 6538 and Klebsiella pneumoniae ATCC 4352 after application to inanimate, non-porous, non-food contact surfaces.

Test Method:

Residual Self-Sanitizing Activity on Hard, Non-Porous Surfaces

[0177]Test Surface Preparation:[0178]Clean glass test surfaces were decontaminated by immersing in reagent alcohol and allowing to air dry at room temperature. The test surfaces were dried in sterile glass petri dishes containing 2 layers of Whatman No. 2 paper. Each petri dish had two surfaces in them and were dried for 1 day in a biological safety cabinet with the lids cracked open.

[0179]Test Surface Inoculation and Coating:[0180]The initial inoculum suspension was prepared by making 10−2 and 10−4 dilutions from a 48-54 hour broth culture of the test system. The 10−4 dilution was all...

example 2

Residual Self-Sanitizing Screen of Test Composition A

[0205]The objective of the analysis was to examine the residual self-sanitizing efficacy of against Staphylococcus aureus ATCC 6538 and Klebsiella pneumoniae ATCC 4352 after application to inanimate, non-porous, non-food contact surfaces.

Test Method:

Residual Self-Sanitizing Activity on Hard, Non-Porous Surfaces

Test System Preparation

[0206]1. At least three consecutive loop transfers of a 24 hour culture of Staphylococcus aureus ATCC 6538 and Klebsiella pneumoniae ATCC 4352 were performed in 10 mL of AOAC Synthetic broth or AOAC Nutrient broth (respectively) and incubated at 35° C.[0207]2. Initial Inoculum Suspension:

[0208]2.1 Vortex a 48-54 hour culture for 3-4 seconds.

[0209]2.2 Make two 1 / 100 dilutions in sterile PBDW and let stand for 15±1 minutes.[0210]3. Reinoculation Suspension:[0211]3.1 Vortex an 18-24 hour culture for 3-4 seconds.[0212]3.2 Make two 1 / 100 dilutions in sterile PBDW and on final dilution of 5.0 mL of diluted c...

example 3

Residual Self-Sanitizing Screen of Test Composition C

[0259]The objective of the analysis was to examine the residual self-sanitizing efficacy of Test composition C (a composition according to the invention) against Staphylococcus aureus ATCC 6538 and Klebsiella pneumoniae ATCC 4352 after application to inanimate, non-porous, non-food contact surfaces.

Test Method:

Residual Self-Sanitizing Activity on Hard, Non-Porous Surfaces

Test System Preparation

[0260]1. At least three consecutive loop transfers of a 24 hour culture of Staphylococcus aureus ATCC 6538 and Klebsiella pneumoniae ATCC 4352 were performed in 10 mL of AOAC Synthetic broth or AOAC Nutrient broth (respectively) and incubated at 35° C.[0261]2. Initial Inoculum Suspension:

[0262]2.1 Vortex a 48-54 hour culture for 3-4 seconds.

[0263]2.2 Make two 1 / 100 dilutions in sterile PBDW and let stand for 15±1 minutes.[0264]3. Reinoculation Suspension:[0265]3.1 Vortex an 18-24 hour culture for 3-4 seconds.[0266]3.2 Make two 1 / 100 dilution...

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Abstract

Anti-microbial compositions comprising (a) a quaternary ammonium compound and (b) a cationic biocide. Applicant has discovered a synergistic combination of the two components with the ration of cationic biocide to quaternary ammonium being less than 1:10 or with a single quaternary compound in a ratio of less than 1.6 to 1 provide a film forming coating that has residual anti-bacterial activity and improved durability with strong resistance to general wear between applications.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS[0001]This application claims priority under 35 U.S.C. §119 to provisional application Ser. No. 61 / 422,908 filed Dec. 14, 2010, herein incorporated by reference in its entirety.FIELD OF THE INVENTION[0002]This invention relates to anti-microbial compositions and use of the same to disinfect or clean various surfaces.BACKGROUND OF THE INVENTION[0003]Microbes may often be present on many common objects and surfaces in everyday life. Microbes can include, for example, bacteria, fungi, spores, viruses, prions, microorganisms such as, e.g., Mycobacterium tuberculosis, listeria monocytogenas, escherichia coli, pseudomonas aeruginosa, salmonella typhimurium, salmonella enteritidis, legionella bacteria, Yersinia pestis, staphylococcus aereus, bacillus subtilis, enterobacter aerogenes, streptococcus faecalis, legionella pneumophila, vibrio parahaemolyticus, bacillus cereus, and other gram positive and gram negative microorganisms. Several such microbes / ...

Claims

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Application Information

Patent Timeline
14 Jun 2012
Publication
US20120148751A1
IPC
B05D5/00; B05D3/10; C09D5/14
CPC
C09D5/14; A01N33/12; A01N25/30; A01N47/44; A01N2300/00; A61P31/04; A01N25/02; A01N25/24
Inventors
HERDT, BRANDON; STAUB, RICHARD