The invention belongs to the technical field of water body oxygen supply equipment and particularly discloses an oxygen supply system for a water body. The oxygen supply system for the water body is composed of a shore oxygen supply component, a gas-liquid dissolving component in the water and a water monitoring component. The oxygen supply system has the following beneficial effects: 1, the deep oxygen supply of the anoxic water zones in a reservoir can be realized, wherein the oxygenating depth is up to 60 m, and the oxygenating efficiency and the oxygenating effect can be obviously increased; 2, while oxygenating, the water body is smoothly diffused, the water bottom sludge cannot be rolled up, the underwater structure cannot be damaged, and the influence on the cultured product in the water bottom can be prevented; 3, the diffusion area is wide, the diffusion radius in the water can be greater than or equal to 1000 m, the oxygenating cover area is large and the production cost is low; 4, the air and the water are highly mixed by a gas-liquid two-phase combining device, so that the oxygen content in the water is high and the oxygen is sufficient; 5, the heights of the water pump and the gas-liquid two-phase combining device are adjusted through a wire rope, so that the oxygenating height is adjusted, the oxygen supplied in layers can be realized and the water quality of the anoxic water zones can be stereoscopically improved; 6, the system is suitable for the anoxic zones of the reservoir, the lake and the sea area and the large-area aquaculture.