The invention provides a
database for guiding individualized
medicine taking of a clinical tumor, a constructing method, a searching method and a device thereof. The constructing method of the
database comprises the steps of acquiring common
data resources of information of a biomarker which is related to
tumor chemotherapy, targeted and immunization
medicine taking guidance; screening and classifying the common
data resources, and obtaining key field and attribute of biomarker information; performing grade classification and dividing on
clinical evidence information; establishing a deciphering
database structure framework of the biomarker which is related with
tumor chemotherapy, targeting and immunization; and recording the information which corresponds with the key field to the corresponding field position of the
database structure framework for obtaining the database for guiding individualized
medicine taking of the clinical tumor. According to the method, the multi-layer biomarkers which are detected through detecting technology such as high-flux sequencing and
immunocytochemistry are comprehensively considered, thereby covering information at aspects of
tumor chemotherapy, targeting and immunization medicine taking guidance, and making
knowledge resource reserving for clinical medical guidance for individualized medicine taking of the tumor.