The application relates to the technical field of medical auxiliary devices, in particular to an adjustable fixing support and method for positioning of a four-limb
soft tissue tumor radiotherapy, which obtains a pressure displacement
time sequence in an initial exploration stage, and filters out a bone support channel and a
soft tissue channel based on calculated terminal tangent stiffness, so that an asymmetric fixing strategy can be used accordingly. By determining a bone locking displacement amount, a rigid reference is established on the bone side first, effectively blocking passive displacement of the bone to the
soft tissue side; a soft tissue locking displacement amount determined based on effective change of
pressure data of the soft tissue channel can quantitatively compensate for rheological properties of the soft tissue and
resist stress relaxation. The asymmetric active locking and rheological compensation
mechanism based on stiffness difference screening overcomes the problems of target area displacement caused by uneven force and fixing failure caused by tissue relaxation in the traditional symmetric clamping, so that the application has higher accuracy for positioning of four-limb soft tissue tumor radiotherapy.