7 results about "Soft tissues tumors" patented technology

The application relates to the technical field of medical auxiliary devices, in particular to an adjustable fixing support and method for positioning of a four-limb soft tissue tumor radiotherapy, which obtains a pressure displacement time sequence in an initial exploration stage, and filters out a bone support channel and a soft tissue channel based on calculated terminal tangent stiffness, so that an asymmetric fixing strategy can be used accordingly. By determining a bone locking displacement amount, a rigid reference is established on the bone side first, effectively blocking passive displacement of the bone to the soft tissue side; a soft tissue locking displacement amount determined based on effective change of pressure data of the soft tissue channel can quantitatively compensate for rheological properties of the soft tissue and resist stress relaxation. The asymmetric active locking and rheological compensation mechanism based on stiffness difference screening overcomes the problems of target area displacement caused by uneven force and fixing failure caused by tissue relaxation in the traditional symmetric clamping, so that the application has higher accuracy for positioning of four-limb soft tissue tumor radiotherapy.

This invention provides a needle for bone and soft tissue tumor biopsy, comprising a needle body, a ring-taking probe, and a pusher. The needle body includes an outer cannula and a core. A channel is formed through the inner part of the outer cannula. The core is inserted into and exits the channel during puncture. The two ends of the outer cannula are a first end and a second end, respectively. The two ends of the core are a third end and a fourth end, respectively. The third end is a needle tip that extends beyond the first end, and the fourth end is used to engage with the second end to form a handle. A depth fixation device is installed on the outer wall of the outer cannula for adsorption onto the tissue surface. The ring-taking probe is inserted into the channel of the outer cannula after the core is removed to extract tissue samples. The distal inner wall surface of the ring-taking probe has a barbed structure. The pusher is inserted into the outer cannula after sample extraction to completely push out any remaining tissue from the outer cannula. This invention can improve the accuracy and comfort of bone and soft tissue tumor biopsy, reduce the sampling failure rate during puncture, and increase the sample volume.

The embodiment of the invention discloses a bone soft tissue tumor repair prosthesis printing method based on a multi-agent decision-making system. The method comprises the following steps: generating tumor knowledge map information according to preset tumor grade screening information, preset tumor grading standard information, acquired tumor-related material information and tumor-related material information; performing change processing on the initialized preset tumor decision intelligent agents to obtain a tumor decision intelligent agent group; generating task processing distribution information according to preset tumor record information and the tumor decision agent group; according to the tumor decision intelligent agent group, the task processing distribution information and the tumor knowledge graph information, prosthesis printing reference information is generated; according to the prosthesis printing reference information, generating a tumor material reconstruction image; and according to the tumor material reconstruction image, controlling a printing device to print a tumor repair prosthesis. According to the implementation mode, the accuracy of the generated prosthesis printing reference information can be improved, and waste of biocompatible materials for 3D printing is reduced.

The present invention relates to a conditionally replicating adenovirus having the E1A gene under expression control of a Survivin promoter, wherein the adenovirus is not defective inthe E3 region and a pharmaceutical composition for treating a bone and soft tissue tumor, containing the conditionally replicating adenovirus as an active ingredient.

The invention belongs to the technical field of intelligent medical assistance, and discloses an AR-based soft tissue tumor resection auxiliary planning method. By introducing a hybrid deep learning model based on SAMMMed and DeepSnake, high-precision tumor segmentation and boundary optimization are realized, and the problem of discontinuous soft tissue image boundaries is solved; a point cloud registration system combining rigid and non-rigid algorithms is constructed, and dynamic alignment and real-time updating of a preoperative model and intra-operative scanning data are achieved; a visualization method based on volume rendering ray casting is adopted, a high-fidelity three-dimensional visualization effect is generated, and a doctor is helped to obtain clear spatial cognition in an operation; an optical navigation system and an augmented reality head display equipment coordinate system are uniformly fused, so that accurate correspondence of virtual-real superposition is realized, and the stability and accuracy of model display in an operation are ensured; a voice recognition and gesture interaction mechanism is introduced, non-contact operation is achieved, the sterile requirement of an operating room is met, and the operation naturalness and convenience are improved.

The invention discloses a soft tissue tumor needle biopsy needle device which comprises a needle tube provided with a piston cavity and a piston axially sliding in an inner cavity of the piston cavity, the piston is connected with a driving part extending to the outside of the needle tube, and a one-way breathable one-way valve tube is arranged on one side of the lower portion of the piston cavity. The lower end of the needle tube is sequentially connected with a pressure stabilizing tube and a buffer tube connected with the pressure stabilizing tube, a needle body is arranged at the lower end of the buffer tube, the pressure stabilizing tube comprises a tube body connected with the needle tube and the buffer tube, the upper portion and the lower portion of the tube body are respectively connected with a fixing plate provided with a plurality of air holes and a sealing block provided with a spherical adaptive through hole, and the lower portion of the fixing plate is fixedly connected with a spring. And the lower end of the spring is fixedly connected with a steel ball matched with the spherical adaptive through hole. According to the tumor tissue sampling needle, normal continuous sampling can be guaranteed, fragmented tumor tissue backflow can be effectively avoided, the total quantity of continuously obtained tumor tissue samples is guaranteed, the needle body can be effectively fixed, shaking of the needle body during continuous sampling is avoided, and safe puncture operation is guaranteed.

A pharmaceutical composition includes a microorganism-derived component. In some embodiments, the microorganism-derived component includes membrane vesicles isolated from a bacterial strain. The pharmaceutical composition can achieve the prevention and treatment of various tumors or cancers, including solid tumors, soft tissue tumors, hematologic tumors, glandular tumors, and metastatic tumors. The pharmaceutical composition demonstrates a prominent immunomodulatory or immunostimulatory effect and an intestinal regulatory function.