The invention relates to a fixing device, and in particular to an infusion hand fixing device. The invention aims at solving a technical problem of providing the infusion hand fixing device, which iscapable of fixing a hand and relieving sourness and numbness of the hand. According to the technical scheme, the infusion hand fixing device comprises a supporting plate, a mounting plate, a sliding sleeve, a sliding rod, a pressing plate, a connecting rod, a clamping pillar, a handle, an airbag, a cylinder body, a piston and the like, wherein a rectangular groove is formed in the left side of thetop of the supporting plate; the mounting plate is connected to the left side of the top of the supporting plate; the mounting plate is arranged at the left side of the rectangular groove; a plurality of round holes are formed in the left side of the upper part of the front side face of the mounting plate; the cylinder body is connected to the left side of the top of the supporting plate; the cylinder body is arranged at the left side of the mounting plate; and the piston is movably arranged in the cylinder body. According to the fixing device provided by the invention, the sliding rod is rotated by medical personnel so as to drive the pressing plate to rotate; the position of the pressing plate can be adjusted in accordance with a hand of a patient, and the hand back of the patient can be fixed; and by continuously the pull rod up and down through pulling, external air can enter the cylinder body, so that the airbag can be continuously inflated.