A kind of preparation method of thiol compound

Abstract

The invention provides a preparation method of a thiol compound. According to the preparation method, gas-liquid reaction is carried out on sulfuretted hydrogen and an organic compound containing carbon-carbon double bonds in a solid base catalyst and a reaction solvent through Michael addition under the conditions that the temperature is 20-80 DEG C and the pressure is 0.10-0.12MPa, so as to prepare the thiol compound. The preparation method is mild in reaction condition; the adopted solid base catalyst is strong in alkalinity; the alkaline catalysis position has relatively strong steric hindrance, and the applicability is wide; the solid base catalyst is easy to filter and recover, and can be repeatedly used after being activated; the reaction conversion rate and the selectivity are high; the side reaction is reduced; and the atomic economic utilization rate of the reaction is high.

Description

technical field

[0001] The invention belongs to the technical field of preparation of thiol compounds, in particular to a gas-liquid phase reaction of hydrogen sulfide and an organic compound containing a carbon-carbon double bond in a solid base catalyst and a reaction solvent through Michael addition under mild reaction conditions Process for the preparation of thiol compounds. Background technique

[0002] Mercaptan is an important organic chemical raw material and organic chemical intermediate. It is widely used in the preparation of pesticide intermediates, pharmaceutical intermediates, optical resins, and chain transfer agents for free radical polymerization. It has a broad market. At present, mercaptan mainly has following 7 kinds of synthetic methods: (1) hydrogen sulfide is raw material method; (2) sodium hydrosulfide (potassium) alkylation method; (3) thiourea method; (4) sodium polysulfide method; ( 5) Sodium thiosulfate method; (6) Sulfate hydrolysis method; (7)...

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