Method for producing pentanediol through selective hydrogenolysis of furan derivative

Abstract

The present invention discloses a method for producing pentanediol through selective hydrogenolysis of a furan derivative. According to the method, a highly dispersed copper-based composite metal oxide is adopted as a catalyst, methanol, ethanol, isopropanol or dioxane is adopted as a solvent, and a furan derivative is subjected to selective hydrogenolysis in an intermittent stirring reaction kettle or continuous fixed bed reactor at a reaction temperature of 120-180 DEG C under a hydrogen pressure of 1-10 MPa to prepare the pentanediol, wherein a catalyst precursor having a hydrotalcite layered structure is subjected to calcination reduction to obtain the catalyst, mainly a metal ion solution having CuM and an alkaline solution are subjected to a co-precipitation reaction so as to obtain the catalyst precursor, and in the catalyst, Cu is the main active component and has the content is 2-40%, and the content of the M-containing oxide and the spinel carrier is 60-98%. According to the present invention, the catalyst preparation method has characteristics of simpleness, easily available raw materials and low cost, and the prepared catalyst has characteristics of uniform component distribution, small particle size, large specific surface area and stable performance, and provides high reaction reactivity and high selectivity for the pentanediol production through the selective hydrogenolysis of the furan derivative.

Description

technical field [0001] The invention belongs to the field of fine chemicals, and relates to a method for preparing pentanediol by selective hydrogenolysis of furan derivatives. Background technique [0002] Both 1,2-pentanediol and 1,5-pentanediol are organic chemicals with a wide range of uses. 1,2-Pentanediol is a linear diol with a dihydroxyl group at one end and a relatively long alkyl chain at the other end. It has obvious polarity and nonpolarity. It is mainly used as a key raw material for the synthesis of the fungicide propiconazole, and also It is an important raw material for the production of polyester fibers, surfactants, pharmaceuticals and other products. In addition, it is used in various skin care products as an excellent moisturizer, preservative and solvent. 1,5-Pentanediol is a linear diol, which has wide application prospects as a polyester and polyurethane monomer; it is also used as an important organic synthesis intermediate for the manufacture of pl...

AI Technical Summary

Problems solved by technology

Chinese patent (CN102627526A) discloses a method of directly hydrogenating α-hydroxy n-valerate to 1,2-pentanediol. Although the yield of this method can reach 95%, the raw material is very scarce and the production cost is high

(2) N-pentene epoxidation method: use n-pentene as raw material, prepare 1,2-epoxypentane through epoxidation, and then hydrolyze and open the ring to obtain 1,2-pentanediol (CN1552684, CN104177230A, US4605795A), this method has problems such as easy generation of by-products, low product yield and serious equipment corrosion

The synthesis methods of 1,5-pentanediol mainly include: (1) Epoxypentenal is prepared by photooxidation of cyclopentadiene, and then obtained by catalytic hydrogenation at 70-100°C under a pressure of about 7MPa, but the cyclopentadiene The low photooxidation efficiency of pentadiene makes this method not economical; (2) Using glutaric acid as raw material, it is first esterified to obtain 1,5-methyl glutarate, and then under the action of CuZnAl catalyst Hydrogenation at 150-350°C and 3-5MPa to produce 1,5-pentanediol (Chinese patents CN03137598.7, CN1565728A)

The conversion rate of this process and the selectivity of 1,5-pentanediol can both be greater than 95%, but the process flow is long and the cost of raw materials is high

(3) Using 1,5-glutaraldehyde as a raw material, hydrogenation is carried out at 60-120°C and 2-8MPa through a supported Ni-based catalyst (CN101225022) or Ru-based catalyst (CN101270032). The selectivity of this method is good, Mild conditions, the disadvantage is that the raw material resources are not abundant and the price is high

Chinese patent CN102872897A discloses a method of using hydrogen-type ultrastable molecular sieve (H-USY) to support Pt to catalyze the hydrogenolysis of furfuryl alcohol to produce 1,5-pentanediol. This method can obtain a yield of nearly 80% of the target product, but the reaction A large amount of precious metal Pt catalyst needs to be added in the process, and the production cost is high

However, the catalyst contains the toxic element Cr, which causes great environmental pollution and harsh reaction conditions.

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