Bone collagen propeptide ammonia sugar pills for increasing bone density and preparation method of bone collagen propeptide ammonia sugar pills

A collagen peptide glucosamine tablet, a technology for increasing bone density, which can be used in medical preparations with non-active ingredients, medical preparations containing active ingredients, bone diseases, etc. The effect of convenience, scientific and reasonable formula, and easy-to-obtain raw material sources

Pending Publication Date: 2017-09-22
江苏江大五棵松生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Technical problem: In order to solve the existing problem of high incidence of osteoporosis and the current situation that most people urgently need to increase bone density, provide a bone collagen peptide aminoglucose tablet for increasing bone density and its preparation method

Method used

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  • Bone collagen propeptide ammonia sugar pills for increasing bone density and preparation method of bone collagen propeptide ammonia sugar pills
  • Bone collagen propeptide ammonia sugar pills for increasing bone density and preparation method of bone collagen propeptide ammonia sugar pills
  • Bone collagen propeptide ammonia sugar pills for increasing bone density and preparation method of bone collagen propeptide ammonia sugar pills

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] (1) After pulverizing 150 parts of marine fish bone collagen oligopeptide powder and 80 parts of D-glucosamine hydrochloride respectively, pass through a 80-mesh sieve and weigh for later use; mix 200 parts of calcium carbonate, 10 parts of chondroitin sulfate, 10 parts of protein phosphopeptide powder, 70 parts of microcrystalline cellulose, 50 parts of dextrin, and 3 parts of micropowdered silica gel were respectively passed through an 80-mesh sieve, and vitamin D 3 0.10 parts passed through a 40-mesh sieve, weighed for later use; weighed 1 part of magnesium stearate, 10 parts of povidone K30, and 10 parts of coating powder for later use;

[0028] (2) Take the above-mentioned vitamin D 3 Mix the fine powder with the same amount of micro-powder silica gel fine powder, and then take the same amount of micro-powder silica gel fine powder as the mixed powder and mix evenly, and increase the amount in this way until they are all mixed evenly and have the same color, and m...

Embodiment 2

[0036] (1) After pulverizing 172.5 parts of marine fish bone collagen oligopeptide powder and 90 parts of D-glucosamine hydrochloride, pass through an 80-mesh sieve, and weigh them for later use; mix 210 parts of calcium carbonate, 30 parts of chondroitin sulfate, 15 parts of protein phosphopeptide powder, 80.5 parts of microcrystalline cellulose, 75.05 parts of dextrin, and 6 parts of micropowdered silica gel were respectively passed through an 80-mesh sieve, and 0.45 parts of vitamin D3 were passed through a 40-mesh sieve, and weighed for later use; 17.5 parts, 17.5 parts of povidone K30, 21 parts of coating powder for subsequent use;

[0037] (2) Mix the above-mentioned fine powder of vitamin D3 with the same amount of micronized silica gel fine powder, and then take the same amount of micronized silica gel fine powder as the mixed powder and mix evenly, so that the amount is increased until all are mixed evenly and the color is consistent. Mixed powder 1 was obtained; case...

Embodiment 3

[0045] (1) After pulverizing 200 parts of marine fish bone collagen oligopeptide powder and 100 parts of D-glucosamine hydrochloride respectively, pass through an 80-mesh sieve and weigh them for later use; mix 250 parts of calcium carbonate, 50 parts of chondroitin sulfate, 20 parts of protein phosphopeptide powder, 100 parts of microcrystalline cellulose, 80 parts of dextrin, and 9 parts of micropowdered silica gel were respectively passed through an 80-mesh sieve, and vitamin D 3 0.5 parts passed through a 40-mesh sieve, weighed for later use; 5 parts of magnesium stearate, 20 parts of povidone K30, and 25 parts of coating powder were weighed for later use;

[0046] (2) The above-mentioned vitamin D 3 Mix the fine powder with the same amount of micro-powder silica gel fine powder, and then take the same amount of micro-powder silica gel fine powder as the mixed powder and mix evenly, and increase the amount in this way until they are all mixed evenly and have the same colo...

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PUM

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Abstract

The invention provides bone collagen propeptide ammonia sugar pills for increasing the bone density. The bone collagen propeptide ammonia sugar pills are at least prepared from the following components: calcium carbonate, D-glucosamine hydrochloride, chondroitin sulfate, marine fish bone collagen low polypeptide powder, vitamin D3, microcrystalline cellulose, dextrin, aerosol, magnesium stearate, povidone K30, hydroxypropyl methyl cellulose, polyethylene glycol and talcum powder. The invention further provides a preparation method of the bone collagen propeptide ammonia sugar pills. The formula provided by the invention is scientific, reasonable, convenient to take and high in palatability; the raw materials are wide in source, safe, nontoxic and free of side effects; the preparation process is simple and feasible and is low in cost and favorable for industrial production.

Description

technical field [0001] The invention belongs to the field of health care products, in particular to health care products for osteoporosis and increasing bone density and a preparation method thereof. Background technique [0002] Osteoporosis is a systemic skeletal disease characterized by decreased bone mass and changes in the microstructure of bone tissue, accompanied by increased bone fragility and increased risk of fracture. It occurs mostly in pregnant women, the elderly and patients with various chronic diseases . According to incomplete statistics, the incidence rate of osteoporosis in the elderly over 60 years old in my country is about 59.89%, and the annual incidence rate of fractures due to osteoporosis is about 9.6%, and there is a trend of increasing year by year. It is predicted that there are about 84 million patients suffering from osteoporosis (including osteopenia) in my country, accounting for 6.6% of the total population, and the prevalence rate can reac...

Claims

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Application Information

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IPC IPC(8): A61K38/39A61K9/36A61K47/38A61P19/10A61K38/17A61K33/10A61K31/737A61K31/7008A61K31/593
CPCA61K38/1709A61K38/39A61K9/2054A61K9/2866A61K31/593A61K31/7008A61K31/737A61K33/10A61K2300/00
Inventor 马海燕李金忠
Owner 江苏江大五棵松生物科技有限公司
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