Supercharge Your Innovation With Domain-Expert AI Agents!

Method for producing long-chain binary acid through fermentation

A long-chain dibasic acid and dibasic acid technology, which is applied in fermentation, nitrogen fertilizer, agriculture, etc., can solve the problems of high complexity of desalination process, increase of production cost, difficulty in treating sodium sulfate solution, etc., and reduce inorganic salt pollution , Reduce the effect of acid-base consumption

Pending Publication Date: 2019-09-24
CATHAY R&D CENT CO LTD +1
View PDF5 Cites 4 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This treatment method contains a ceramic membrane filtration process, but the process conditions have the following disadvantages: after the fermentation of the long-chain dibasic acid, a large amount of caustic soda needs to be used to adjust the pH to form a long-chain dibasic acid sodium salt
Sodium sulfate solution is difficult to deal with, and the existing environmental protection regulations do not allow it to be discharged into nature. It can only be dried by evaporation to form a large amount of low-quality sodium sulfate solids, which are accumulated and stored.
The input of alkali and acid, on the one hand, increases the production cost, on the other hand, acid and alkali form salt, and the existence of salt increases the manpower and material cost of the post-treatment process, and the desalination process is very complicated, and improper treatment will damage the The environment has a very adverse impact and also greatly hinders the production of long-chain dibasic acids

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-6

[0087] Get Candida Tropicalis (Candida Tropicalis) CAT H1614 (preservation number is CCTCC M 2013143) glycerol tube strain inoculation in the seed bottle that is equipped with 30ml YPD liquid culture medium (glucose 2%, yeast extract 1%, peptone 2%) Medium, natural pH, culture at 29°C, 220rpm shaker for 1 day. Get shake flask seed access and be equipped with 5L seed culture medium (sucrose 2%, corn steep liquor 0.3%, yeast extract 0.5%, KH 2 PO 4 0.8%, urea 0.3%) in the seed tank, the inoculation amount is 10%, the initial pH value of the system after inoculation is 6.0, at 29°C, the ventilation rate is 0.4vvm, the tank pressure is 0.08MPa, and the culture is 18h. Naturally drops to 3.

[0088] OD 620When it grows to 0.7 (diluted 30 times), it is inoculated into fermentation medium containing (glucose 4%, corn steep liquor 0.5%, yeast extract 0.4%, potassium nitrate 1%, potassium dihydrogen phosphate 0.1%, urea 0.12%, ammonium sulfate 0.06% and sodium chloride 0.1%) in th...

Embodiment 1

[0089] Embodiment 1~6 is respectively: according to above-mentioned fermentation technology, undecane (embodiment 1), dodecane (embodiment 2), tridecane (embodiment 3), tetradecane (embodiment 4), pentadecane (embodiment 5) and hexadecane (embodiment 6) were fermented to obtain corresponding long-chain dibasic acids, and the output results are shown in Table 1.

[0090] Table 1

[0091] craft raw material long chain dibasic acid Fermentation cycle / h Acid production / mg / g Example 1 C11 alkanes DC11 151 110.4 Example 2 C12 alkanes DC12 132 152.6 Example 3 C13 alkanes DC13 135 137.2 Example 4 C14 alkanes DC14 128 155.1 Example 5 C15 alkanes DC15 136 143.1 Example 6 C16 alkanes DC16 148 134.8

[0092] Compared with the above-mentioned fermentation process of Examples 1-6 and the fermentation process under traditional alkaline conditions (that is, when the pH of the fermentation conversion period...

Embodiment 7

[0097] The method for preparing the long-chain dibasic acid is the same as that of Example 2, the difference being that: the received film serum is added at 60°C with 5wt% powdered activated carbon (relative to the amount of the long-chain dibasic acid contained in the solution) ) was decolorized and filtered to obtain a clear liquid. Add sulfuric acid to adjust the pH to 3.2, lower the temperature to 30°C, filter to obtain a wet solid, wash the filter cake with pure water 3 times the weight of the wet solid, filter and dry to obtain a crude product of dodecanedioic acid.

[0098] The obtained ammonium sulfate aqueous solution was filtered, evaporated and concentrated to an ammonium sulfate content of 45wt% by using a multi-effect evaporator, cooled to crystallize, plate and frame filtered, and dried to obtain ammonium sulfate crystals for sale.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a method for producing a long-chain binary acid through fermentation. The method is characterized in that the pH of fermentation thalli at the growth period is 3.0 or above and is preferably 3.5-6.5, and the pH of the fermentation thalli at the fermentation transition phase is 7.0 or below and is preferably 4.0-6.8 and is more preferably 5.0-6.5; after fermentation is completed, the pH value of long-chain binary acid fermentation liquid is controlled to be 7.0 or above through ammonia water, liquid ammonia or ammonia gas, and fermentation liquid containing a long-chain binary acid ammonium salt is obtained; and through membrane filtration, acidification, and solid-liquid separation, the long-chain binary acid is extracted. Under the premise of guaranteeing high yield of long-chain binary acid products, the consumption of alkali liquid in the process of fermentation and production is effectively reduced, so that the content of inorganic salts in a final solution is reduced; and besides, an ammonium salt solution can be further concentrated to form chemical fertilizers, or can directly enter a sewage treatment plant, so that the sewage treatment pressure is greatly alleviated.

Description

technical field [0001] The present invention relates to a method for producing long-chain dibasic acids. Specifically, the present invention relates to a method for fermentatively producing long-chain dibasic acids. Background technique [0002] Long-chain dibasic acids are the basic monomer raw materials for a series of synthetic materials. Long-chain dibasic acids and their derived monomers can be used to produce nylon, polycarbonate, powder coatings, spices, hot melt adhesives, special lubricants, etc. It is an important raw material for synthetic spices, engineering plastics, cold-resistant plasticizers, high-grade lubricants and polyamide hot-melt adhesives. [0003] During the preparation of long-chain dibasic acids, long-chain dibasic acid salts are usually formed first in the reaction solution, and a series of treatments need to be performed on the reaction solution containing long-chain dibasic acid salts to obtain long-chain dibasic acid products . [0004] In t...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C12P7/64C05C3/00
CPCC12P7/6409C05C3/00
Inventor 秦兵兵李乃强杨晨徐敏郝英利刘修才
Owner CATHAY R&D CENT CO LTD
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com