17 results about "Operative behandlung" patented technology

The invention provides a biomarker for predicting the recurrence risk of papillary thyroid carcinoma and application of the biomarker, and a proteomics method is utilized to analyze proteins with significant abundance level difference in blood of two groups of people with papillary thyroid carcinoma recurrence and non-recurrence after papillary thyroid carcinoma patients are subjected to operative treatment, so that the papillary thyroid carcinoma recurrence risk can be predicted, and the papillary thyroid carcinoma recurrence risk can be predicted. According to the method, a biomarker capable of being used for predicting the papillary thyroid carcinoma recurrence risk is screened out, and a multi-marker joint detection model is further constructed, so that the papillary thyroid carcinoma recurrence risk can be accurately, noninvasively and efficiently predicted, and clinical requirements are met.

The invention provides a prediction method for the effect of treating gastric superficial early-stage neoplastic lesions, and relates to the technical field of treatment effect prediction. Comprising the steps of performing initial image scanning on a to-be-treated patient to obtain a preoperative image set; performing parameter sequence extraction on the preoperative image set to obtain an initial parameter sequence set; obtaining an initial derivative parameter set according to the initial parameter sequence set; performing operative treatment on the to-be-tested patient according to the derivative parameter set to obtain the to-be-tested patient; performing secondary image scanning on the patient to be detected to obtain a postoperative image set; performing parameter sequence extraction on the postoperative image set to obtain a secondary parameter sequence set; obtaining a secondary derivative parameter set according to the secondary parameter sequence set; obtaining a first ROI map and a second ROI map according to the derivative parameter set and the secondary derivative parameter set; and inputting the first ROI map and the second ROI map into a treatment effect prediction model to obtain a prediction result. The problem of low treatment effect prediction precision in the prior art is solved.

The utility model discloses a biopsy puncture device, and belongs to the technical field of medical instruments.In the biopsy puncture device, a limiting piece is arranged on a second component, and the limiting piece is used for limiting a first component, so that the first component can drive the second component to move towards a third component; the guide pipe is connected with the second component, so that the guide pipe can move along with the second component; the puncture needle can be connected with the first component, so that the first component drives the puncture needle to move when moving, the catheter can be driven to penetrate through the tissue together when the puncture needle punctures, the puncture needle can be withdrawn, the catheter is left in the tissue for subsequent operative treatment, and damage to the tissue in an operation is reduced.

The utility model provides a minimally invasive spine retractor, which belongs to the technical field of medical instruments and comprises a retraction mechanism, the retraction mechanism comprises a base, a middle-layer ring body and an upper-layer ring body, the middle-layer ring body is positioned between the base and the upper-layer ring body, and three limiting openings are formed in the middle-layer ring body at equal intervals in a surrounding manner. A plurality of limiting openings are formed in the middle layer ring body, each limiting opening is movably connected with a distraction frame, a notch is formed in the edge of one side of the middle layer ring body, an elastic piece is arranged in the notch, a positioning block is arranged on the elastic piece, positioning holes are connected to the positioning block in a clamped mode, and the positioning holes are formed in the lower side of the upper layer ring body and distributed at equal intervals. The instrument can be introduced into the body, a channel reaching the focus is rapidly established, meanwhile, the degree of tissue opening is automatically positioned, operation can be conducted with one hand, convenience and rapidness are achieved, the safety and reliability of channel establishment are improved, the structure is simple and stable, and certain practical value is achieved.

The invention discloses a minimally invasive surgery treatment system for benign prostatic hyperplasia and a use method of the minimally invasive surgery treatment system. The system comprises an outer cannula used for entering the body of a patient through the urethra, a handle connected to the outer cannula, a cannula installed in the outer cannula, a stretching tube installed in the cannula, a guide wire installed in the stretching tube, a puncture needle head installed at the free end of the guide wire, a rotation driving mechanism used for driving the guide wire to rotate and a telescopic driving mechanism used for driving the cannula to move. A plurality of cutting knives which are uniformly arranged around the stretching tube are arranged between the free end of the stretching tube and the puncture needle head; a magnetic ring which is magnetically attracted with the puncture needle head is arranged at the free end of the sleeve; a guide wire locking mechanism used for locking the guide wire and a stretching pipe adjusting and locking mechanism used for adjusting the position of the stretching pipe and locking the stretching pipe are further arranged in the handle. The system is reasonable in structural design, the telescopic cutting knife is integrated into the puncture assembly, when the system is used for operation, trauma is small, recovery is fast, only local anesthesia is needed, the effect is fast, and the operation effect is good.

The present disclosure relates to the treatment of non-small cell lung cancer (NSCLC). More specifically, the disclosurerelates to the treatment of patients having an NSCLC by administering a treatment regimen that includes an anti-TIGIT antagonist antibody (e.g., tiragolumab) and a PD-1 axis binding antagonist (e.g., atezolizumab) following surgical resection and adjuvant chemotherapy or by administering a treatment regimen that includes an adjuvant chemotherapy, an anti-TIGIT antagonist antibody (e.g., tiragolumab), and a PD-1 axis binding antagonist (e.g., atezolizumab) following surgical resection.

At present, the treatment methods for sarcoidosis include operative treatment, radiochemical treatment and drug treatment (including traditional Chinese medicine decoction). Wherein the operative treatment has a good curative effect on early-stage patients, but the treatment cost is high; the treatment effect on advanced patients is poor; traditional Chinese medicine decoction is long in conditioning time and slow in treatment speed. In order to better treat nodule diseases and overcome the defects in the prior art, the invention provides the liqueur for treating nodules, which can effectively treat various nodules, and has the advantages of simultaneous treatment of medicine and food, small side effect, low cost and good curative effect.

A movement restriction composition for use in a method of treatment of reflux disease treatment by surgery, the movement restriction composition comprising 50% - 100% silicone or 50% - 100% polyurethane. A coronal plane of the patient divides the esophagus of the patient in an anterior half and a posterior half. The treatment by surgery comprises dissecting an area of the patient's stomach, affixing the stomach fundus wall to the lower part of the patient's esophagus by providing sutures or staples, creating a pouch in the stomach fundus wall, and placing and in-vaginating the movement restriction composition in the pouch by providing sutures or staples to the stomach fundus wall. The center of gravity of the movement restriction composition can be positioned dorsal to the coronal plane for preventing the cardia from sliding through the patient's diaphragm opening into the patient's thorax.

The invention relates to the technical field of medical data mining, and provides a prostate cancer recurrence risk prediction system based on multi-modal data, which comprises the following steps: collecting physiological parameters and discomfort moments of a prostate cancer patient after operative treatment, marking a target discomfort moment, and obtaining an adjacent discomfort moment of the target discomfort moment; acquiring a rising and falling ratio of the same type of physiological parameters at the target discomfort moment; dividing and updating abnormal data expression intervals; determining the comprehensive convolution kernel scale of the prostatic cancer patient at the target discomfort moment according to the correlation between any two different types of physiological parameters, the time length of the abnormal data representation interval of the physiological parameters and the rising and falling ratio of all types of physiological parameters at the target discomfort moment; and predicting the prostate cancer recurrence risk of the prostate cancer patient according to the comprehensive convolution kernel scale. According to the invention, effective management of the recurrence risk of prostate cancer can be realized.

The utility model provides a needle holding device, and relates to the technical field of medical instruments, and the needle holding device comprises a base which is fixed relative to the skin of a target body and is provided with two arc grooves which are oppositely arranged; the supporting disc is of an arc-shaped structure, the two ends of the supporting disc are provided with sliding blocks in sliding fit with the two oppositely-arranged arc grooves, and the sliding blocks slide in the arc grooves so that the supporting disc can rotate in the arc direction relative to the base; the needle holding clamp is provided with a body, a needle groove formed in the first face of the body and a clamping arm which is arranged on the second face of the body and extends away from the first face, and the clamping arm can be clamped on the supporting disc in a reciprocating sliding mode along the arc-shaped supporting disc; the locking assembly comprises a first locking structure used for locking the supporting disc and the base, a second locking structure used for locking the needle holding clamp and the supporting disc, and a third locking structure used for being matched with the needle groove to lock the medical needle. The stability of the medical needle in the operation process is enhanced, the operation burden of an operator is reduced, and the puncture accuracy and the operation treatment effect are improved.

The utility model relates to a cyst stripping leakproof puncture suction catheter, which comprises an outer sleeve, a puncture tube and an expansion piece operation tube, the puncture tube is hermetically sleeved in the outer sleeve through a sealing component, the front end side of the outer sleeve is provided with an abutting hole, and one side of the rear end of the outer sleeve, which is close to the sealing component, is provided with a first negative pressure hole; a puncture hole is formed in the front end of the puncture tube, a second negative pressure hole is formed in the rear end of the puncture tube, and an expansion piece is installed on the side, close to the front end, of the puncture tube. The expansion piece operation tube is fixedly arranged in the puncture tube in a sleeved mode and connected with the expansion piece. By means of the cyst stripping catheter, substances in the cyst can be effectively prevented from overflowing through the expansion piece operation tube and the corresponding using method, and therefore effective cyst stripping operation treatment is conducted on a patient.

The invention discloses an integrated targeted vertebral kyphoplasty system, comprising a puncture head, a tube body and a tube body handle; one end of the tube body is connected to the puncture head, a balloon is arranged on the end of the tube body connected to the puncture head, and a guide is arranged on the tube body at one end of the balloon; the other end of the tube body is connected to the tube body handle, and a guide knob for controlling the bending of the guide and a pressure pump connector for communicating with the balloon are arranged on the end of the tube body connected to the tube body handle; a cement outlet is arranged on the puncture head, a cement channel is arranged at the center of the tube body, a cement inlet is arranged on the tube body handle, and the cement outlet, the cement channel and the cement inlet are connected. The device only needs one puncture and can complete the entire KP surgical treatment without changing any tools, which greatly reduces the patient's intraoperative radiation exposure rate and the pain caused by multiple operations.

The invention provides an absorbable anal fistula repair assembly and a preparation method and application thereof. The absorbable anal fistula repair assembly comprises a first sheet layer and a second sheet layer which are prepared from degradable materials and are independent from each other, preferably, a third sheet layer is also included. The anal fistula repair component is characterized in that the first sheet layer carries an immunomodulator, the second sheet layer carries a regeneration repair regulator, the third sheet layer carries antibiotics, the complete degradation time is 2-4 weeks, the second sheet layer carries an immunomodulator, the complete degradation time is 4-12 weeks, the first sheet layer carries a regeneration repair regulator, and the complete degradation time is 12-26 weeks, so that staged and layered degradation of the anal fistula repair component and layer-by-layer release of drugs or preparations are realized. Experimental results show that the absorbable anal fistula repairing assembly is good in mechanical property, anti-inflammatory effect and cell proliferation promoting effect, the defects that medicine treatment is long in period and slow in curative effect are overcome, the very tedious operation steps of cleaning, dressing changing, debridement and disinfection every day after operative treatment are avoided, and the absorbable anal fistula repairing assembly is suitable for popularization and application. The life quality and the physical and psychological health of the patient can be improved.

The utility model discloses an abdominal cavity suction tube, and particularly relates to the technical field of suction devices for abdominal cavity surgeries, the abdominal cavity suction tube comprises a suction tube and an exhaust tube, the exhaust tube is sleeved outside the suction tube, an air inlet channel is formed between the exhaust tube and the suction tube, two ends of the exhaust tube are fixedly connected with the outer wall of the suction tube in a sealing mode, and the suction tube is provided with an inlet and an outlet. The inlet is communicated with the outside and used for stretching into the abdominal cavity and sucking hydrops in the abdominal cavity, the outlet is used for being in sealed connection and communication with an aspirator pipe, the side wall, close to the outlet, of the exhaust pipe is fixedly connected and communicated with an air inlet pipe in a sealed mode, the air inlet pipe can provide air for the exhaust pipe, and a plurality of exhaust holes are formed in the side wall, close to the inlet, of the exhaust pipe. And gas in the exhaust pipe can be exhausted through the exhaust hole. The omentum drainage tube can prevent omentum, viscera and other tissues from blocking the suction tube in an operation, reduces damage to omentum tissues, ensures smooth drainage process, relieves pain of a patient, and improves the overall effect of operation treatment.

The invention provides a low-estrogen ovarian cancer co-disease depression animal model and a construction method thereof, and belongs to the technical field of medicine. The method first establishes an abdominal cavity transplantation tumor by injecting an ovarian cancer cell suspension into the abdominal cavity of a female mouse. And then, after the tumor is formed, performing bilateral ovariectomy to simulate the persistent hypoestrogen state of the ovarian cancer patient caused by operative treatment. And finally, inducing the mouse to generate depression-like behavior phenotypes through chronic constraint stress. The model solves the limitation that an existing model cannot accurately simulate a tumor-low estrogen-depression three-in-one pathological mechanism of an ovarian cancer patient. Experiments prove that the model successfully reproduces the coexistence characteristics of tumor progression acceleration, obvious reduction of estrogen level and typical depression-like behaviors, and provides a reliable research platform for deeply researching the pathogenesis of ovarian cancer co-disease depression and developing a new treatment strategy.

The invention relates to a nano-drug for treating aseptic loosening of a bone implant and a preparation method of the nano-drug. The nano-drug comprises an STING inhibitor C-176 and a layered double hydroxide LDH, and the C-176 is adsorbed to a layer gap or a surface of the LDH space structure through an intermolecular force. According to the invention, the occurrence of aseptic inflammation of the bone implant and the development of loosening of the implant can be obviously reduced, and the clinical prognosis of a patient is improved. Compared with the prior art, the invention has higher clinical adaptability, and is particularly suitable for patients who cannot be subjected to operative treatment. In addition, the use method is easy and convenient to operate, small in side effect and capable of effectively improving the living quality of the patient and reducing the treatment cost.

The utility model discloses a sealing structure for a guidewire main tube of a Y-tube connector for interventional surgery. A roller is connected in a rolling manner inside a sealing shell, and a rolling groove of the roller is inclined so that the guidewire catheter is pressed or kept away from the guidewire catheter during the rolling process of the roller. A catheter groove is provided at the bottom of the sealing shell, and a guidewire groove is provided at the bottom of the catheter groove. A catheter convex ring is convexly provided on the outer wall of the roller, and a guidewire ring groove is provided in the middle of the catheter convex ring. The problem in the prior art that the sealing structure cannot adapt to the structure of the guidewire and cannot ensure the sealing effect under the interference of the guidewire is solved. The guidewire catheter sealing structure of the Y-tube connector for interventional surgery has a reasonable overall structural design, can meet the smooth passage of the guidewire catheter, and can leave enough passing space for the guidewire during the compression and sealing process. Moreover, a catheter groove and a catheter convex ring are provided in the compression and sealing of the guidewire catheter to ensure the maximum compression and deformation of the catheter, thereby meeting the sealing effect of the guidewire catheter.