17 results about "Stroke recovery" patented technology

The invention, which relates to the technical field of medical training, discloses a multi-sensory feedback fusion stroke rehabilitation exoskeleton robot training system comprising an exoskeleton robot main body, a multi-sensory feedback module, and a motion state monitoring module. By integrating a multi-sensory feedback module, a visual, auditory, tactile and motion state monitoring module and a central control module, multi-dimensional sensory stimulation and real-time data acquisition are realized when a patient is trained, and the central control module adapts parameters in the module according to the real-time motion precision of the patient and personalization. The strength and the type of multi-sensory feedback are dynamically adjusted, meanwhile, motion parameters of an exoskeleton robot body are controlled, a dynamic adjustment mechanism ensures pertinence and effectiveness of training, forward feedback is provided to strengthen a correct motion mode when the motion precision of a patient is high, and correction prompt is provided and assistance or resistance of the robot is adjusted when the motion deviation is large. Therefore, nerve function remodeling and motor ability recovery are effectively promoted.

The present invention relates to an apparatus for treating neurological or psychiatric disorders using i-wave periodicity-dependent Quadri-Pulse Theta Burst Stimulation (iQPS). The system comprises a transcranial magnetic stimulation (TMS) stimulator configured to deliver test pulses to a target motor cortical area and therapeutic theta bursts to a treatment area with pulse frequency tailored to the patient's individual i-wave periodicity. An electromyography (EMG) device records motor evoked potentials (MEPs) from a target muscle and analyzes the intervals between MEPs to determine the i-wave periodicity. The personalized stimulation enhances cortical plasticity by synchronizing stimulation with the brain's intrinsic neural timing. The invention is applicable to neurological and psychiatric conditions that include depression, schizophrenia, stroke recovery and neuropathic pain. Advantages include improved treatment efficacy, reduced variability in patient response and a non-invasive, adaptive therapy model that aligns with the patient's unique neurophysiological characteristics, offering a precise and scalable approach to brain stimulation.

Methods and systems for improving medical conditions by delivering a focused ultrasound signal to target sites of the brain. The focused ultrasound signal can have a mechanical index of between about 1.0 to about 8.0 and / or an acoustic pressure of between about 1.0 MPa to about 3.0 MPa. The medical condition can comprise addiction (including binge eating), anxiety disorders and anxiety associated disorders, tinnitus, neurodegenerative disorders, neuropsychiatric disorders, cognitive disorders, neurodevelopmental disorders, post-traumatic stress disorder, stroke recovery, and combinations thereof.

The invention provides a chemical entity of Formula (I):wherein R1, R2, X, Y and Z have any of the values described herein, and compositions comprising such chemical entities; methods of making them; and their use in a wide range of methods as disclosed herein, including metabolic and reaction kinetic studies; detection and imaging techniques; radioactive treatments; modulating and treating disorders mediated by PDE2 activity; treating neurological disorders, CNS disorders, dementia, neurodegenerative diseases, and trauma-dependent losses of function; treating stroke, including cognitive and motor deficits during stroke rehabilitation; facilitating neuroprotection and neurorecovery; enhancing the efficiency of cognitive and motor training, including animal skill training protocols; and treating peripheral disorders, including hematological, cardiovascular, gastroenterological, and dermatological disorders.

The invention discloses an information processing method and device for evaluating a stroke rehabilitation treatment scheme. The method comprises the following steps: performing causal effect identification based on a causal effect inference model; performing neural rehabilitation prognosis score estimation based on the causal effect recognition result; and performing neurological rehabilitation prognosis score adjustment based on the score estimation result to screen out a plurality of treatment exposure comparison objects. Through a cause and effect inference model and an analysis method based on a prognosis scoring framework, the method can adapt to various rehabilitation intervention modes accepted by stroke patients in a real clinical environment, and through simulation of prognosis risks under different rehabilitation paths, curative effect comparison and individualized prognosis evaluation under non-random data are realized. And the scientificity and the accuracy of rehabilitation scheme decision making are improved.

This invention relates to an instrument for treating neurological or psychiatric disorders using i-wave periodicity-dependent four-pulse theta burst stimulation (iQPS). The system includes a transcranial magnetic stimulation (TMS) stimulator configured to deliver test pulses to a target motor cortex region and therapeutic theta bursts to a treatment region, wherein the pulse frequency is customized according to the patient's individual i-wave periodicity. An electromyography (EMG) device records motor evoked potentials (MEPs) from the target muscles and analyzes the intervals between MEPs to determine the i-wave periodicity. Personalized stimulation enhances cortical plasticity by synchronizing stimulation with the brain's intrinsic neural timing. This invention is applicable to neurological and psychiatric conditions including depression, schizophrenia, stroke recovery, and neuropathic pain. Advantages include improved therapeutic efficacy, reduced patient response variability, and a non-invasive adaptive therapy model aligned with the patient's unique neurophysiological characteristics, thus providing a precise and scalable approach to brain stimulation.

The application discloses an auxiliary stroke rehabilitation method and device based on a multi-source physiological signal wearable device, and the method comprises the following steps: monitoring the pulse waveform variation rate and the sublingual vein characteristic parameters of a subject through a self-powered five-zang monitoring wristband; dynamically evaluating the zang-fu imbalance index of the subject according to the pulse waveform variation rate and the sublingual vein characteristic parameters; generating individualized rehabilitation adjustment parameters according to the zang-fu imbalance index of the subject; synchronously collecting the electroencephalogram signal and the surface electromyogram signal of a target muscle of the subject, and generating an acupoint activation time sequence atlas corresponding to a preset hand movement; optimizing the acupoint activation time sequence atlas according to the individualized rehabilitation adjustment parameters, so as to adjust the acupoint selection, the stimulation intensity and the stimulation time sequence; and presenting an embedded stomach meridian of foot yangming virtual acupuncture scene to the subject through a VR guide instrument. The application integrates the brain and muscle electrical cooperative decoding, the individualized parameter adjustment, the VR and the zang-fu imbalance traditional Chinese medicine diagnosis method into the rehabilitation scheme, and the rehabilitation effect of stroke rehabilitation is improved.

The application discloses an offline chart stroke recovery method and system, and belongs to the technical field of chart recognition. In order to solve the technical problems of incomplete stroke recovery, false connection and false merging caused by cross connection, local fracture, continuous writing and multi-graph element adhesion in an offline chart image, the application obtains an offline chart image and pre-processes the offline chart image to obtain a pre-processed chart image; center line extraction and stroke segment division are performed on the pre-processed chart image to obtain a skeleton image and candidate stroke segments; junction point detection is performed on the skeleton image, and the candidate stroke segments are classified according to the junction point detection to obtain a to-be-reconstructed stroke segment group; the connection degrees between the stroke segments in the to-be-reconstructed stroke segment group are calculated according to stroke segment features, and reconnection is performed to obtain candidate strokes; feature analysis is performed on the candidate strokes to determine split points, and the candidate strokes are cut according to the split points to obtain a recovered chart stroke set. The application improves the integrity and instance separability of chart stroke recovery.

This invention relates to a gait recognition and classification method, apparatus, electronic device, and storage medium. The gait recognition and classification method of this invention includes: preprocessing an image sequence from a gait video to obtain a skeleton energy image corresponding to the gait video; extracting features from the skeleton energy image to obtain a feature vector corresponding to the skeleton energy image; and classifying the feature vector using a trained classification network to obtain a classification result corresponding to the gait video; the classification result includes normal, first hemiplegic gait, second hemiplegic gait, and third hemiplegic gait. The gait recognition and classification method of this invention, based on gait analysis of video, provides automatic and even portable gait detection and classification to assist in assessing stroke recovery progress.

The present invention relates to an apparatus for treating neurological or psychiatric disorders using i-wave periodicity-dependent Quadri-Pulse Theta Burst Stimulation (iQPS). The system comprises a transcranial magnetic stimulation (TMS) stimulator configured to deliver test pulses to a target motor cortical area and therapeutic theta bursts to a treatment area with pulse frequency tailored to the patient's individual i-wave periodicity. An electromyography (EMG) device records motor evoked potentials (MEPs) from a target muscle and analyzes the intervals between MEPs to determine the i-wave periodicity. The personalized stimulation enhances cortical plasticity by synchronizing stimulation with the brain's intrinsic neural timing. The invention is applicable to neurological and psychiatric conditions that include depression, schizophrenia, stroke recovery and neuropathic pain. Advantages include improved treatment efficacy, reduced variability in patient response and a non-invasive, adaptive therapy model that aligns with the patient's unique neurophysiological characteristics, offering a precise and scalable approach to brain stimulation.

The invention discloses an intelligent hand drum for elderly and stroke rehabilitation training, and relates to the technical field of rehabilitation instruments for artificial intelligence technology and traditional African drum music culture, the intelligent hand drum comprises a beating area, a sound box area and a control area, the beating area is installed at the upper end of the sound box area, and the control area is installed at the lower end of the sound box area; three pressure touch sensors are mounted in the striking area and are used for acquiring striking position, strength and time sequence data of a user and respectively generating a low-pitch signal and two alto-pitch signals; the striking area is electrically connected with the sound box area; and the external pedal touch control sensor is electrically connected with the control area and is used for generating an additional rhythm sound effect. The intelligent hand drum for rehabilitation training of old people and stroke assists a user in converting music entertainment into a valuable health management tool through long-term tracking and analysis, and promotes cognitive health and physical and mental coordination development.

The utility model provides a simple and easy stroke recovery period speech function rehabilitation training device, include: winding wind bag, blow pipe and display component, blow pipe is connected in winding wind bag one end, display component sets up in blow pipe and winding wind bag, display component includes two fixed plate, two scale line, support and fixed ring, two scale line is respectively set up in the surface of two fixed plate, support is connected between two fixed plate, fixed ring is connected in one end of support and is located blow pipe connection. The utility model provides a simple and easy stroke recovery period speech function rehabilitation training device, sets up two fixed plate, two scale line, support and fixed ring on the surface of winding wind bag with blow pipe, can check the size of winding wind bag through the scale line on the surface of fixed plate when the patient blows winding wind bag through blow pipe and moves,

Methods and systems for improving medical conditions by delivering a focused ultrasound signal to target sites of the brain. The focused ultrasound signal can have a mechanical index of between about 1.0 to about 8.0 and / or an acoustic pressure of between about 1.0 MPa to about 3.0 MPa. The medical condition can comprise addiction (including binge eating), anxiety disorders and anxiety associated disorders, tinnitus, neurodegenerative disorders, neuropsychiatric disorders, cognitive disorders, neurodevelopmental disorders, post-traumatic stress disorder, stroke recovery, and combinations thereof.

The invention belongs to the technical field of biological medicines, and discloses a mud moxibustion preparation for adjuvant therapy of joint functions of stroke rehabilitation patients and a preparation method of the mud moxibustion preparation. The mud moxibustion preparation is a qi-tonifying and blood-activating formula with astragalus membranaceus and ligusticum wallichii as the core, the pathological core of a qi deficiency and blood stasis type stroke rehabilitation patient is precisely met, and rehabilitation requirements are met from the source. According to the preparation method of the mud moxibustion preparation for adjuvant therapy of the joint function of the stroke rehabilitation patient, the crushing granularity is accurately controlled through a process end, the redundant process is simplified, and high efficiency of industrial preparation is achieved. The matrix is selected from auxiliary materials meeting the medical-grade safety standard, no adverse reaction is caused by skin irritation tests, the formed product is stable in texture, and the product is not prone to falling off when attached to the curved surface of the joint. The finished product compulsively passes a microbial limit test (the total number of bacteria is less than or equal to 100cfu / g, and the total number of mould and saccharomycetes is less than or equal to 10cfu / g), completely conforms to the safety specification of medical auxiliary materials, and can meet the safety requirement of a patient for long-term use according to a treatment course.

One embodiment provides a neurorestoration compound or composition implementing multiple neuroplasticity inducing mechanisms of action including a mixture of pharmacologically effective amounts of Cilostazol and Metformin and Telmisartan. A second embodiment provides a neurorestoration compound or composition implementing multiple neuroplasticity inducing mechanisms of action including a mixture of pharmacologically effective amounts of Cilostazol and Metformin and Duloxetine. The neurorestoration compound implementing multiple neuroplasticity inducing mechanisms of action is believed to be particularly well suited for stroke rehabilitation.

Disclosed are means of inducing and accelerating neurological recovery subsequent to a stroke through administration of amniotic fluid derived stem cells. In one embodiment stem cells are isolated from amniotic fluid and expanded under conditions allowing for expression of SSEA3, SSEA4, Tra1-60, Tra1-81, Tra2-54, Oct-4 and CD105. Said cells are subsequently administered into a patient having undergone a stroke, so as to induce direct regeneration (through transdifferentiation and replacement of neural tissue), as well as indirect regeneration (through production of growth factors that augment endogenous regenerative mechanisms while inhibiting degenerative mechanisms). In some embodiments factors produced by said amniotic fluid stem cells may be utilized instead of cells themselves. Said factors may include proteins, peptides, conditioned media, exosomes, or microvesicles.

The invention pertains to a magnetic sorting toy designed for children's color and number recognition, as well as therapeutic applications. The toy comprises a transparent top plate, a middle labyrinth layer, and a bottom MDF plate, combined with an attached magnetic pen or plastic finger mold to assist children or individuals with limited fine motor skills. Magnetic balls of different colors are moved through the labyrinth's channels into corresponding storage grooves, reinforcing color sorting, counting, and number recognition. This toy is also suitable for therapeutic use in stroke recovery, occupational therapy, and fine motor rehabilitation, offering tactile and kinesthetic learning benefits. The various textures, colors, and customizable designs make it versatile for educational and therapeutic purposes.