Medical dental implant with surface biomimetic function and manufacturing method thereof

Abstract

The invention relates to a medical dental implant with the surface biomimetic function and a manufacturing method thereof. The medical dental implant is characterized in that the medical dental implant comprises an implant body and further comprises an outer layer of a bionic artificial bone structure, the outer layer is integrally combined with the outer surface of the implant body and capable of simulating the alveolar cavity bone tissue structure around the tooth root portion of a missing tooth of a patient. According to the medical dental implant and the manufacturing method thereof, the outer layer of the bionic bone structure, which is formed in a 3D printing mode and of a massive structure, serves as the outer layer of the tooth implant body, and therefore an ideal embodiment used for simulating the artificial bone surface structure is provided. More importantly, a good activity surface layer structure foundation beneficial to bone marrow stem cell and bone-formation related cell adhesion, proliferation and growth and capable of playing the final bone-formation function is provided, the surface of the foundation is loaded with chemical components such as calcium and phosphate and bioactive molecules such as collagens, hence, a bone-formation promotion microenvironment is created, bone cell generation is induced, and fast and firm bone combination can be achieved at the early stage.

Description

technical field [0001] The invention belongs to a biomedical dental implant, in particular to a medical dental implant with surface bionics and a manufacturing method thereof. Background technique [0002] With the increase of traffic accidents and population aging, tooth loss caused by various reasons in the population is increasing year by year. With the improvement of people's living standards, people's requirements for the restoration and replacement of missing teeth are increasing. Due to the rapid development of current implant technology, dental implants have been widely used in the restoration of dentition defects and missing teeth. In order to achieve sufficient strength, metal or alloy implants are usually placed in the missing teeth to replace the missing teeth and restore beauty and function. In stomatology, etc., pure titanium metal (or alloy) is widely used in the field of oral implants because of its good biocompatibility, mechanical properties and corrosion...

AI Technical Summary

Problems solved by technology

However, there is a problem: these metals or alloys are biologically inert, and it is difficult to form a fast and good osseointegration with bone tissue, which leads to prolonged healing period after implantation, low bonding strength, and even implantation failure.

[0023] The problem with sand blasting and acid etching is that there are reagent pollution and unclean environmental protection problems in the acid etching process

[0045] The problem with the sol-gel method is that the coating is prone to cracking

The prepared coating is well bonded to the substrate, has high hardness and strength, and has certain toughness, but the uniformity and stability of the coating are difficult to control

[0048] The problem with the laser method is that it is difficult to control the uniformity and stability of the coating, and it is not easy to mass produce

[0063] The state and stability of A bioactive molecules are difficult to control

[0064] B biologically active molecules absorb quickly, have poor specificity, and the mechanism of action is unknown

[0065] C The existing technology has high cost and low production efficiency

[0066] Comprehensive defect of the prior art: Although the prior art all aims to add bioactive molecules (increase collagen and other bioactive components) from the physical structure (rough surface appearance) and chemical composition (increase calcium and phosphorus content) through implant surface treatment. ) angle to simulate the structure of natural bone tissue, so as to improve the biocompatibility of the implant surface through bionic means, but after all, it is quite different from the structure of natural bone tissue, so it is impossible to obtain a three-dimensional porous network bone tissue structure, so Also unable to achieve effective addition of chemically and biologically active molecules

An important defect in the existing technologies is the lack of a carrier structure that is as bionic as the natural bone tissue as the surface layer of the implant, so that the chemical and biological active components can be effectively anchored on the implant surface, and finally the ideal Early rapid and strong osseointegration

The surface-treated titanium implants in the prior art not only have many disadvantages such as difficulty in forming chemical bonds with tissues in the early stage of implantation, slow osseointegration formation, and long healing period, but also have strong randomness in the processing process and uneven surface treatment results. , poor stability and difficult to control; after the coating is prepared, it cannot maintain stability for a long time, and it is prone to problems such as dissolution, falling off, and pollution during processing; the state of biologically active molecules is unstable, poor specificity, and low production efficiency.

In addition, there are also problems such as strong corrosiveness of processing reagents, environmental pollution, and adverse effects on personnel health and environmental protection.

Images