Unlock instant, AI-driven research and patent intelligence for your innovation.

A preparation method of a parathion sensor based on two-dimensional nanomaterials

A technology of two-dimensional nanomaterials and parathion, which is applied to the analysis of materials, electrochemical variables of materials, and material analysis through electromagnetic means. It can solve the problems of cumbersome process and low yield, and achieve simple preparation, low cost, and Effect of improving resonance energy transfer capability

Inactive Publication Date: 2019-03-12
UNIV OF JINAN
View PDF5 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, most of the synthesis methods are synthesized separately, and then compound the catalyst and the carrier, the process is cumbersome and the yield is not high

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Example 1 Co-TiO 2 / MoS 2 preparation of

[0041] (1) Add 0.6 g of molybdenum disulfide powder and 0.2 mmol of cobalt salt to 3 mL of n-butyllithium solution, and stir for 12 hours under nitrogen protection at 60 °C to obtain the reacted solution;

[0042] (2) Wash the reacted solution in step (1) with a non-polar solvent, and then perform ultrasonic treatment in a water bath at 60 °C. After the treatment, wash the treated solution with a non-polar solvent, and dry it in vacuum to obtain cobalt Intercalated molybdenum disulfide nanomaterials;

[0043] (3) Add 500 mg of cobalt-intercalated molybdenum disulfide nanomaterials prepared in step (2) into 5 mL of tetrabutyl titanate, stir for 1 hour, slowly add 0.5 mL of hydrofluoric acid while stirring, and then Reaction in the reactor at 160°C for 18 hours;

[0044] (4) The reaction product obtained in step (3) was centrifuged and washed three times with ultrapure water and absolute ethanol, and then vacuum-dried at 50 °...

Embodiment 2

[0049] Example 2 Co-TiO 2 / MoS 2 preparation of

[0050] (1) Add 0.6 g of molybdenum disulfide powder and 1.0 mmol of cobalt salt into 5 mL of n-butyllithium solution, and stir for 24 hours under nitrogen protection at 30 °C to obtain the reacted solution;

[0051] (2) Wash the reacted solution in step (1) with a non-polar solvent, and then perform ultrasonic treatment in a water bath at 30 °C. After the treatment, wash the treated solution with a non-polar solvent, and dry it in vacuum to obtain cobalt Intercalated molybdenum disulfide nanomaterials;

[0052] (3) Add 200 mg of cobalt-intercalated molybdenum disulfide nanomaterials prepared in step (2) into 5 mL of tetrabutyl titanate, stir for 1 hour, then slowly add 0.6 mL of hydrofluoric acid while stirring, and then Reaction in the reactor at 180°C for 20 hours;

[0053] (4) The reaction product obtained in step (3) was centrifuged and washed three times with ultrapure water and absolute ethanol, and then vacuum-dried ...

Embodiment 3

[0058] Example 3 Preparation method of parathion sensor

[0059] (1) ITO conductive glass with a width of 1 cm and a length of 4 cm was used as a working electrode, and 8 µL of Co-TiO was drop-coated on the surface of the electrode 2 / MoS 2 Sol, dry at room temperature;

[0060] (2) Wash the electrode obtained in step (1) with the buffer solution PBS, continue to drip-coat 8 µL of 10 µg / mL parathion antibody solution on the surface of the electrode, and store it in a refrigerator at 4 °C to dry;

[0061] (3) Wash the electrode obtained in step (2) with PBS, continue to drip-coat 8 µL of bovine serum albumin solution with a concentration of 100 µg / mL on the surface of the electrode, and store it in a refrigerator at 4 °C to dry;

[0062] (4) Wash the electrode obtained in step (3) with PBS, store it in a refrigerator at 4°C and dry it, and then prepare the parathion sensor;

[0063] The Co-TiO 2 / MoS 2 The sol is 50 mg of Co-TiO 2 / MoS 2 The powder was dissolved in 10 mL...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
concentrationaaaaaaaaaa
Login to View More

Abstract

The invention discloses a preparation method of an electrochemiluminescent parathion sensor. It belongs to the technical field of new nanometer functional materials and biosensors. The present invention firstly prepares a novel two-dimensional nanocomposite material—titanium dioxide / molybdenum disulfide composite material, that is, a two-dimensional nanocomposite material CoTiO2 / MoS2 in which cobalt-doped titanium dioxide nano-squares are in-situ compounded with molybdenum disulfide. The material has good biocompatibility and large specific surface area, and it is loaded with parathion antibody. During the detection, because cobalt-doped titanium dioxide can catalyze hydrogen peroxide to generate O2 in situ, and conduct electrolysis with K2S2O8 in the bottom liquid. The chemical reaction generates an electrochemiluminescence signal, and then uses the effect of the specific quantitative combination of the antibody and the antigen on the electron transport ability to reduce the current intensity, thereby reducing the luminescence intensity, and finally realizes the detection by the label-free electrochemiluminescence method Construction of an electrochemiluminescence sensor for parathion.

Description

technical field [0001] The invention relates to a preparation method of an electrochemiluminescent parathion sensor. It belongs to the technical field of new nanometer functional materials and biosensors. Background technique [0002] Parathion is a broad-spectrum highly toxic insecticide, which has contact killing, stomach poisoning and fumigation effects, and can penetrate into plants. Parathion acts quickly on insects and can be used to control cotton, apple, citrus, pear, peach and other fruit tree pests and wheat red spiders. In the soil, parathion can migrate slightly to the deep layer of the soil through the leaching of water. Parathion in the soil can enter the plant through absorption by plant roots. After people eat such plants or plants containing their residues by mistake, parathion can enter the human body through the digestive tract, respiratory tract and intact skin and mucous membranes, causing nausea, vomiting, headache, diarrhea, and general weakness. S...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): G01N27/26G01N27/327
CPCG01N27/26G01N27/327
Inventor 张勇马洪敏杜斌胡丽华庞雪辉
Owner UNIV OF JINAN