A composition with the effect of preventing and treating complications of dialysis patients, its preparation method and its application
A composition and complication technology, applied in the field of biomedicine, can solve the problems of increased preparation process complexity and production costs, hyperkalemia complications, frequent use, etc., to avoid complications or adverse reactions, control blood sugar levels, The effect of improving nutritional status
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Embodiment 1
[0115] Example 1 Composition and proportioning research of the composition of the present invention
[0116] Weigh the required amount of raw materials according to Table 1, and mix them uniformly with a mixer to prepare compositions A-R. According to the method described in the present invention, the protein and energy content of the composition A-R is measured, and the blood phosphorus content is detected by the phosphomolybdic acid method, and the blood potassium content is detected by the ion selective electrode method, and the protein energy supply ratio is 10-20%. 7 Group compositions A, B, C, D, J, K, M.
[0117] 140 subjects were selected from patients with kidney disease who underwent hemodialysis three times a week for more than 3 months, and the subjects were aged 32-68 years. 140 patients were randomly divided into 7 groups, 20 cases in each group, there was no significant difference in age, etiology, course of disease, dialysis program, nutritional status, etc. ...
Embodiment 2
[0126] Example 2 Preparation of the composition of the present invention The components and proportions of the compositions 1-3 of the present invention are shown in Table 3.
[0127] Table 3 Components and proportioning ratio of compositions 1-3 of the present invention
[0128] Numbering Whey protein (g) Casein (g) Maltodextrin (g) corn syrup (g) Sunflower oil (g) Composition 1 15 15 15 4 51 Composition 2 23 5 35 6 31 Composition 3 23 5 25 4 43
[0129] Note: The composition of casein (g) used in Table 3 is sodium caseinate: calcium caseinate with a mass ratio of 1:3.5.
[0130] The preparation method of the composition 1-3 of the present invention: take the required amount of whey protein, sodium caseinate, calcium caseinate, maltodextrin, corn syrup and sunflower oil according to Table 3, and mix them evenly with a mixer , that is.
Embodiment 3
[0131] Example 3 Composition of the present invention is used to treat complications of chronic renal failure dialysis patients
[0132] 1. Test patients
[0133] 120 patients with nephropathy who underwent hemodialysis three times a week and had hemodialysis for more than 3 months were selected as test patients. There were 23 cases of episodic glomerulonephritis, 5 cases of hypertensive benign arteriolar nephrosclerosis, 4 cases of aristolochic acid nephropathy and 2 cases of unknown etiology. Among the 120 tested patients, 76% were mildly or moderately malnourished, and 24% were severely malnourished.
[0134] 2. Experimental method
[0135] Each group of patients in the test received treatment guidance, and corresponding symptomatic treatment was given according to the specific conditions of the test patients, including anti-infection, blood sugar control, blood pressure control, and anemia correction. The test patients continued to take the composition of the present ...
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