The invention relates to the technical field of medical equipment, and discloses a respirator and a using method thereof. The respirator comprises an expiration flow sensor, an air supply flow sensorand a plurality of pressure sensors, a central processing unit, pressure adjusting equipment, an air supply gun and an exhalation valve, wherein the pressure sensors are used for measuring the air supply flow pressure and the expiration flow pressure and arranged on an air supply pipe and an expiration pipe; the central processing unit is used for receiving the data of the air supply flow sensor and the expiration flow sensor, comparing, integrating and calculating the data of the air supply flow and the expiration flow, and controlling the pressure adjusting equipment according to the integrated and calculated data and the data of the plurality of pressure sensors; the pressure adjusting equipment is used for adjusting the pressure of the air supply flow according to an instruction of thecentral processing unit and adjusting the pressure of the air supply flow; the air supply gun is used for conveying airflow with corresponding pressure according to data of the pressure adjusting equipment; and the exhalation valve is used for controlling and exhausting exhalation air flow. According to the respirator and the using method, the treatment success rate of the ARDS patient can be increased.